The ocular albinism type 1 gene product is a membrane glycoprotein localized to melanosomes
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L-DOPA is an endogenous ligand for OA1The melanosomal/lysosomal protein OA1 has properties of a G protein-coupled receptorThe ocular albinism type 1 (OA1) G-protein-coupled receptor functions with MART-1 at early stages of melanogenesis to control melanosome identity and compositionAn unconventional dileucine-based motif and a novel cytosolic motif are required for the lysosomal and melanosomal targeting of OA1Differential actin-dependent localization modulates the evolutionarily conserved activity of Shroom family proteinsBiochemical characterization of arylsulfatase E and functional analysis of mutations found in patients with X-linked chondrodysplasia punctataThe microphthalmia transcription factor (Mitf) controls expression of the ocular albinism type 1 gene: link between melanin synthesis and melanosome biogenesisNew insights into ocular albinism type 1 (OA1): Mutations and polymorphisms of the OA1 geneThe ocular albinism type 1 protein, an intracellular G protein-coupled receptor, regulates melanosome transport in pigment cellsG protein-coupled receptor genes in the FANTOM2 databaseInvolvement of OA1, an intracellular GPCR, and G alpha i3, its binding protein, in melanosomal biogenesis and optic pathway formationSignaling pathways in melanosome biogenesis and pathologyChaperoning G protein-coupled receptors: from cell biology to therapeuticsSpecific interaction of Gαi3 with the Oa1 G-protein coupled receptor controls the size and density of melanosomes in retinal pigment epithelium.Spectrum of candidate gene mutations associated with Indian familial oculocutaneous and ocular albinism.Autoimmunity and the immunotherapy of cancer: targeting the "self" to destroy the "other".Development of the retina and optic pathway.A constitutively active Gαi3 protein corrects the abnormal retinal pigment epithelium phenotype of Oa1-/- miceAbnormal crossing of the optic fibres shown by evoked magnetic fields in patients with ocular albinism with a novel mutation in the OA1 gene.L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functionsMechanisms of protein delivery to melanosomes in pigment cells.Amino acid starvation induces reactivation of silenced transgenes and latent HIV-1 provirus via down-regulation of histone deacetylase 4 (HDAC4)Melanoregulin, product of the dsu locus, links the BLOC-pathway and OA1 in organelle biogenesis.The ocular albinism type 1 gene product, OA1, spans intracellular membranes 7 timesOcular Albinism Type 1 Regulates Melanogenesis in Mouse Melanocytes.Molecular genetic and clinical evaluation of three Chinese families with X-linked ocular albinism.Albinism in Europe.Functional Characterization of the Odorant Receptor 51E2 in Human Melanocytes.Identification and characterization of a melanocyte-specific novel 65-kDa peripheral membrane protein.Comment on "Identification of Novel G Protein-Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism".Expression of OA1 limits the fusion of a subset of MVBs with lysosomes - a mechanism potentially involved in the initial biogenesis of melanosomes.Influence of tyrosinase levels on pigment accumulation in the retinal pigment epithelium and on the uncrossed retinal projection.GPCR signalling from within the cell.GPR143Gene Mutation Analysis In Pediatric Patients With AlbinismBiogenesis of Melanosomes
P2860
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P2860
The ocular albinism type 1 gene product is a membrane glycoprotein localized to melanosomes
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on August 1996
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
The ocular albinism type 1 gen ...... otein localized to melanosomes
@en
The ocular albinism type 1 gen ...... tein localized to melanosomes.
@nl
type
label
The ocular albinism type 1 gen ...... otein localized to melanosomes
@en
The ocular albinism type 1 gen ...... tein localized to melanosomes.
@nl
prefLabel
The ocular albinism type 1 gen ...... otein localized to melanosomes
@en
The ocular albinism type 1 gen ...... tein localized to melanosomes.
@nl
P2093
P2860
P356
P1476
The ocular albinism type 1 gen ...... otein localized to melanosomes
@en
P2093
A Ballabio
C Baschirotto
C Tacchetti
M V Schiaffino
S Montalti
P2860
P304
P356
10.1073/PNAS.93.17.9055
P407
P577
1996-08-01T00:00:00Z