Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents.
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Alterations to melanocortinergic, GABAergic and cannabinoid neurotransmission associated with olanzapine-induced weight gainFrom the Cover: Antipsychotic drug-induced weight gain mediated by histamine H1 receptor-linked activation of hypothalamic AMP-kinaseRNA sequencing reveals a slow to fast muscle fiber type transition after olanzapine infusion in ratsOlanzapine-induced hyperphagia and weight gain associate with orexigenic hypothalamic neuropeptide signaling without concomitant AMPK phosphorylationAn evaluation of the effects of the novel antipsychotic drug lurasidone on glucose tolerance and insulin resistance: a comparison with olanzapineMetabolic side-effects of the novel second-generation antipsychotic drugs asenapine and iloperidone: a comparison with olanzapine.Olanzapine promotes fat accumulation in male rats by decreasing physical activity, repartitioning energy and increasing adipose tissue lipogenesis while impairing lipolysis.Atypical antipsychotics rapidly and inappropriately switch peripheral fuel utilization to lipids, impairing metabolic flexibility in rodents.The impact of antipsychotic drugs on food intake and body weight and on leptin levels in blood and hypothalamic ob-r leptin receptor expression in wistar rats.Lipid-lowering effects of tetradecylthioacetic acid in antipsychotic-exposed, female rats: challenges with long-term treatmentA novel mechanism and treatment target for presynaptic abnormalities in specific striatal regions in schizophreniaIn vivo pharmacological evaluations of novel olanzapine analogues in rats: a potential new avenue for the treatment of schizophreniaMetformin and berberine prevent olanzapine-induced weight gain in ratsA double blind, placebo-controlled, randomized crossover study of the acute metabolic effects of olanzapine in healthy volunteers.Antipsychotics inhibit glucose transport: Determination of olanzapine binding site in Staphylococcus epidermidis glucose/H(+) symporter.Central nervous system delivery of the antipsychotic olanzapine induces hepatic insulin resistanceEffect of Serum Leptin on Weight Gain Induced by Olanzapine in Female Patients with SchizophreniaAcute Metabolic Effects of Olanzapine Depend on Dose and Injection Site.Chronic clozapine reduces rat brain arachidonic acid metabolism by reducing plasma arachidonic acid availability.H3 histamine receptor antagonist pitolisant reverses some subchronic disturbances induced by olanzapine in mice.Effect of chronic infusion of olanzapine and clozapine on food intake and body weight gain in male and female rats.Weight gain and changes in metabolic variables following olanzapine treatment in schizophrenia and bipolar disorder.The role of hypothalamic H1 receptor antagonism in antipsychotic-induced weight gain.Modelling olanzapine-induced weight gain in rats.Recent evidence and potential mechanisms underlying weight gain and insulin resistance due to atypical antipsychotics.Atypical antipsychotics and effects on feeding: from mice to men.Zonisamide prevents olanzapine-associated hyperphagia, weight gain, and elevated blood glucose in rats.Ameliorative Effect of Curcumin on Olanzapine-induced Obesity in Sprague-Dawley Rats.Artesunate prevents rats from the clozapine-induced hepatic steatosis and elevation in plasma triglycerides.Acute effects of olanzapine on behavioural expression including the behavioural satiety sequence in female rats.Effect of lactational exposure of olanzapine on body weight of mice: a comparative study on neonates of both the sexes during post-natal development.Antipsychotic-induced metabolic effects in the female rat: Direct comparison between long-acting injections of risperidone and olanzapine.Lack of Ovarian Secretions Reverts the Anabolic Action of Olanzapine in Female Rats.Roman high and low avoidance rats differ in their response to chronic olanzapine treatment at the level of body weight regulation, glucose homeostasis, and cortico-mesolimbic gene expression.Effects of naltrexone on food intake and body weight gain in olanzapine-treated rats.Effects of olanzapine in male rats: enhanced adiposity in the absence of hyperphagia, weight gain or metabolic abnormalities.No evidence for binding of clozapine, olanzapine and/or haloperidol to selected receptors involved in body weight regulation.Gender-dependent consequences of chronic olanzapine in the rat: effects on body weight, inflammatory, metabolic and microbiota parameters.Attenuated Weight Gain with the Novel Analog of Olanzapine Linked to Sarcosinyl Moiety (PGW5) Compared to Olanzapine.Olanzapine, but not aripiprazole, weight-independently elevates serum triglycerides and activates lipogenic gene expression in female rats.
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Hormonal and metabolic effects of olanzapine and clozapine related to body weight in rodents.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2006
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
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name
Hormonal and metabolic effects ...... ted to body weight in rodents.
@en
Hormonal and metabolic effects ...... ted to body weight in rodents.
@nl
type
label
Hormonal and metabolic effects ...... ted to body weight in rodents.
@en
Hormonal and metabolic effects ...... ted to body weight in rodents.
@nl
prefLabel
Hormonal and metabolic effects ...... ted to body weight in rodents.
@en
Hormonal and metabolic effects ...... ted to body weight in rodents.
@nl
P2093
P2860
P356
P1433
P1476
Hormonal and metabolic effects ...... ted to body weight in rodents.
@en
P2093
Andras Hajnal
Beth Halle
Cathy R Henry
Christopher J Lynch
Nicholas T Bello
Susan L Lynch
Vance L Albaugh
P2860
P356
10.1038/OBY.2006.6
P577
2006-01-01T00:00:00Z