Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.
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Disease severity and mortality can be independently regulated in a mouse model of experimental graft versus host diseaseInterleukin-18 regulates acute graft-versus-host disease by enhancing Fas-mediated donor T cell apoptosisDownregulation of T-bet/GATA-3 ratio induced by IL-11 treatment is responsible for Th1/Th2 balance restoration in human immune thrombocytopenic purpura (ITP).Dexamethasone palmitate ameliorates macrophages-rich graft-versus-host disease by inhibiting macrophage functions.Immunization with host-type CD8{alpha}+ dendritic cells reduces experimental acute GVHD in an IL-10-dependent manner.Recipient-type specific CD4+CD25+ regulatory T cells favor immune reconstitution and control graft-versus-host disease while maintaining graft-versus-leukemiaSeparating graft-versus-leukemia from graft-versus-host disease in allogeneic hematopoietic stem cell transplantation.Siglec-G-CD24 axis controls the severity of graft-versus-host disease in mice.Antigen-specific CD8+ T cell feedback activates NLRP3 inflammasome in antigen-presenting cells through perforin.IL-11 separates graft-versus-leukemia effects from graft-versus-host disease after bone marrow transplantation.Differential roles of IL-1 and TNF-alpha on graft-versus-host disease and graft versus leukemia.Interleukin-11 therapy selectively downregulates type I cytokine proinflammatory pathways in psoriasis lesions.The biology of graft-versus-host disease: experimental systems instructing clinical practice.Th2 and Tc2 cells in the regulation of GVHD, GVL, and graft rejection: considerations for the allogeneic transplantation therapy of leukemia and lymphoma.Dysfunction of bone marrow vascular niche in acute graft-versus-host disease after MHC-haploidentical bone marrow transplantation.NKT cell-dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs.Harnessing graft-versus-malignancy: non-myeloablative preparative regimens for allogeneic haematopoietic transplantation, an evolving strategy for adoptive immunotherapy.Donor lymphocyte infusions to treat hematologic malignancies in relapse after allogeneic blood or marrow transplantation.STAT3 signaling in CD4+ T cells is critical for the pathogenesis of chronic sclerodermatous graft-versus-host disease in a murine modelIL-11 expression in retinal and corneal cells is regulated by interferon-gamma.The Wnt agonist R-spondin1 regulates systemic graft-versus-host disease by protecting intestinal stem cells.Blockade of osteopontin reduces alloreactive CD8+ T cell-mediated graft-versus-host diseaseMurine cytomegalovirus immediate-early 1 gene expression correlates with increased GVHD after allogeneic hematopoietic cell transplantation in recipients reactivating from latent infection.Sequential activation of inflammatory signaling pathways during graft-versus-host disease (GVHD): early role for STAT1 and STAT3.Mucosal tissue injury in cancer therapy. More than muscositis and mouthwash.Separating graft-versus-tumor from graft-versus-host reactions.Pretransplant CSF-1 therapy expands recipient macrophages and ameliorates GVHD after allogeneic hematopoietic cell transplantationHuman mesenchymal stromal cells attenuate graft-versus-host disease and maintain graft-versus-leukemia activity following experimental allogeneic bone marrow transplantation.HDAC inhibition and graft versus host diseaseKinetics of gene expression in murine cutaneous graft-versus-host disease.'GVHD': graft-versus-host disease or graft-versus-Hodgkin's disease? An old acronym with new meaning.Role of cytokines as a double-edged sword in sepsisAbsence of Stat1 in donor CD4⁺ T cells promotes the expansion of Tregs and reduces graft-versus-host disease in miceInduction of acute GVHD by sex-mismatched H-Y antigens in the absence of functional radiosensitive host hematopoietic-derived antigen-presenting cells.LPS antagonism reduces graft-versus-host disease and preserves graft-versus-leukemia activity after experimental bone marrow transplantation.Immune restoration following hematopoietic stem cell transplantation: an evolving target.Recent advances in the treatment of graft-versus-host disease.Pathophysiology of acute graft-versus-host disease: recent advances.ST2 blockade reduces sST2-producing T cells while maintaining protective mST2-expressing T cells during graft-versus-host disease.The S1P1 receptor-selective agonist CYM-5442 reduces the severity of acute GVHD by inhibiting macrophage recruitment.
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Interleukin-11 promotes T cell polarization and prevents acute graft-versus-host disease after allogeneic bone marrow transplantation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on July 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Interleukin-11 promotes T cell ...... c bone marrow transplantation.
@en
Interleukin-11 promotes T cell ...... c bone marrow transplantation.
@nl
type
label
Interleukin-11 promotes T cell ...... c bone marrow transplantation.
@en
Interleukin-11 promotes T cell ...... c bone marrow transplantation.
@nl
prefLabel
Interleukin-11 promotes T cell ...... c bone marrow transplantation.
@en
Interleukin-11 promotes T cell ...... c bone marrow transplantation.
@nl
P2093
P2860
P356
P1476
Interleukin-11 promotes T cell ...... ic bone marrow transplantation
@en
P2093
Brinson YS
Crawford JM
Ferrara JL
Keith JC Jr
P2860
P304
P356
10.1172/JCI3132
P407
P577
1998-07-01T00:00:00Z