Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses.
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Regulation of T-cell receptor signaling by the actin cytoskeleton and poroelastic cytoplasmVav family exchange factors: an integrated regulatory and functional viewThe N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.Mechanism and function of Vav1 localisation in TCR signalling.Spatial association of signaling proteins and F-actin effects on cluster assembly analyzed via photoactivation localization microscopy in T cellsMultimolecular analysis of stable immunological synapses reveals sustained recruitment and sequential assembly of signaling clustersVav1 Regulates T-Cell Activation through a Feedback Mechanism and Crosstalk between the T-Cell Receptor and CD28.Vav1 oncogenic mutation inhibits T cell receptor-induced calcium mobilization through inhibition of phospholipase Cγ1 activationA Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation.The linker for activation of T cells (LAT) signaling hub: from signaling complexes to microclustersA TIRF microscopy technique for real-time, simultaneous imaging of the TCR and its associated signaling proteins.Signaling for synergistic activation of natural killer cells.The N-terminal 20-amino acid region of guanine nucleotide exchange factor Vav1 plays a distinguished role in T cell receptor-mediated calcium signaling.Activation of extracellular signal-regulated kinase but not of p38 mitogen-activated protein kinase pathways in lymphocytes requires allosteric activation of SOS.CD25 and CD69 induction by α4β1 outside-in signalling requires TCR early signalling complex proteins.Multipoint binding of the SLP-76 SH2 domain to ADAP is critical for oligomerization of SLP-76 signaling complexes in stimulated T cells.Complementary phosphorylation sites in the adaptor protein SLP-76 promote synergistic activation of natural killer cells"Cell biology meets physiology: functional organization of vertebrate plasma membranes"--the immunological synapse.
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Vav1-mediated scaffolding interactions stabilize SLP-76 microclusters and contribute to antigen-dependent T cell responses.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 08 March 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Vav1-mediated scaffolding inte ...... en-dependent T cell responses.
@en
Vav1-mediated scaffolding inte ...... en-dependent T cell responses.
@nl
type
label
Vav1-mediated scaffolding inte ...... en-dependent T cell responses.
@en
Vav1-mediated scaffolding inte ...... en-dependent T cell responses.
@nl
prefLabel
Vav1-mediated scaffolding inte ...... en-dependent T cell responses.
@en
Vav1-mediated scaffolding inte ...... en-dependent T cell responses.
@nl
P2093
P2860
P1433
P1476
Vav1-mediated scaffolding inte ...... en-dependent T cell responses.
@en
P2093
Ken Nguyen
Nicholas R Sylvain
Stephen C Bunnell
P2860
P356
10.1126/SCISIGNAL.2001178
P577
2011-03-08T00:00:00Z