Inherited interleukin 12 deficiency in a child with bacille Calmette-Guérin and Salmonella enteritidis disseminated infection.
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A natural mutation in the Tyk2 pseudokinase domain underlies altered susceptibility of B10.Q/J mice to infection and autoimmunityA large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genesRole of IL-12 in Staphylococcus aureus-triggered arthritis and sepsisInnate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune CellsMendelian susceptibility to mycobacterial disease: genetic, immunological, and clinical features of inborn errors of IFN-γ immunityEvolution of M. bovis BCG Vaccine: Is Niacin Production Still a Valid Biomarker?Genetics of susceptibility to human infectious diseaseMycobacterium tuberculosis lipoarabinomannan-mediated IRAK-M induction negatively regulates Toll-like receptor-dependent interleukin-12 p40 production in macrophagesReview of ustekinumab, an interleukin-12 and interleukin-23 inhibitor used for the treatment of plaque psoriasisResidual type 1 immunity in patients genetically deficient for interleukin 12 receptor beta1 (IL-12Rbeta1): evidence for an IL-12Rbeta1-independent pathway of IL-12 responsiveness in human T cellsT cell-mediated host immune defenses in the lungAnaerobic nitrate reductase (narGHJI) activity of Mycobacterium bovis BCG in vitro and its contribution to virulence in immunodeficient miceSTAT4 serine phosphorylation is critical for IL-12-induced IFN-gamma production but not for cell proliferationEarly interferon-γ production in human lymphocyte subsets in response to nontyphoidal Salmonella demonstrates inherent capacity in innate cellsA safe vaccine (DV-STM-07) against Salmonella infection prevents abortion and confers protective immunity to the pregnant and new born miceMolecular analysis of idiopathic subglottic stenosis for Mycobacterium species.Genetic susceptibility to tuberculosis.Chronic helminth infections may negatively influence immunity against tuberculosis and other diseases of public health importance.A novel form of cell type-specific partial IFN-gammaR1 deficiency caused by a germ line mutation of the IFNGR1 initiation codon.Optimized expression and specific activity of IL-12 by directed molecular evolution.Acquired predisposition to mycobacterial disease due to autoantibodies to IFN-gamma.Novel STAT1 alleles in otherwise healthy patients with mycobacterial disease.Dynamic changes in pro- and anti-inflammatory cytokine profiles and gamma interferon receptor signaling integrity correlate with tuberculosis disease activity and response to curative treatment.Innate defects of the IL-12/IFN-γ axis in susceptibility to infections by mycobacteria and salmonellaInheritable defects in interleukin-12- and interferon-gamma-mediated immunity and the TH1/TH2 paradigm in man.IRAK1BP1 inhibits inflammation by promoting nuclear translocation of NF-kappaB p50.Fluorescent acid-fast microscopy for measuring phagocytosis of Mycobacterium avium, Mycobacterium intracellulare, and Mycobacterium scrofulaceum by Tetrahymena pyriformis and their intracellular growth.Non-major histocompatibility complex control of antibody isotype and Th1 versus Th2 cytokines during experimental infection of mice with Mycobacterium avium.Gamma interferon-producing CD4+ T lymphocytes in the lung correlate with resistance to infection with Mycobacterium tuberculosis.Human macrophage activation programs induced by bacterial pathogens.Clinical consequences of defects in the IL-12-dependent interferon-gamma (IFN-gamma) pathway.Type 1/Type 2 immunity in infectious diseases.Increased sensitivity to Salmonella enterica serovar Typhimurium infection in mice undergoing withdrawal from morphine is associated with suppression of interleukin-12.Gamma interferon is dispensable for neopterin production in vivoActivation and repression of interleukin-12 p40 transcription by erythroid Kruppel-like factor in macrophages.Association between the tumor necrosis factor locus and the clinical outcome of Leishmania chagasi infectionImpaired interferon gamma-mediated immunity and susceptibility to mycobacterial infection in childhood.Probable disseminated BCG infection in a 10-month-old child after BCG vaccinationGuidelines for genetic studies in single patients: lessons from primary immunodeficiencies.Cytokines and immunodeficiency diseases.
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P2860
Inherited interleukin 12 deficiency in a child with bacille Calmette-Guérin and Salmonella enteritidis disseminated infection.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on December 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Inherited interleukin 12 defic ...... itidis disseminated infection.
@en
Inherited interleukin 12 defic ...... itidis disseminated infection.
@nl
type
label
Inherited interleukin 12 defic ...... itidis disseminated infection.
@en
Inherited interleukin 12 defic ...... itidis disseminated infection.
@nl
prefLabel
Inherited interleukin 12 defic ...... itidis disseminated infection.
@en
Inherited interleukin 12 defic ...... itidis disseminated infection.
@nl
P2093
P2860
P50
P356
P1476
Inherited interleukin 12 defic ...... itidis disseminated infection.
@en
P2093
Casanova JL
Darbyshire P
Drysdale P
Döffinger R
Girdlestone J
Kumararatne DS
Lamhamedi S
P2860
P304
P356
10.1172/JCI4950
P407
P577
1998-12-01T00:00:00Z