A Single-Cell Transcriptome Atlas of the Human Pancreas.
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Transcriptome analysis of pancreatic cells across distant species highlights novel important regulator genes.Is a β cell a β cell?Genomics of Islet (Dys)function and Type 2 Diabetes.All mixed up: defining roles for β-cell subtypes in mature islets.The Importance of REST for Development and Function of Beta Cells.Heterogeneity of the Pancreatic Beta CellBeta cell heterogeneity: an evolving concept.Systematic single-cell analysis provides new insights into heterogeneity and plasticity of the pancreas.Human beta cell mass and function in diabetes: Recent advances in knowledge and technologies to understand disease pathogenesis.Interrogating islets in health and disease with single-cell technologiesDifferent developmental histories of beta-cells generate functional and proliferative heterogeneity during islet growth.Alpha TC1 and Beta-TC-6 genomic profiling uncovers both shared and distinct transcriptional regulatory features with their primary islet counterparts.Single-Cell Gene Expression Analysis of a Human ESC Model of Pancreatic Endocrine Development Reveals Different Paths to β-Cell Differentiation.Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns.Multiplexed droplet single-cell RNA-sequencing using natural genetic variation.Adult Murine Pancreatic Progenitors Require Epidermal Growth Factor and Nicotinamide for Self-Renewal and Differentiation in a Serum- and Conditioned Medium-Free Culture.Unravelling biology and shifting paradigms in cancer with single-cell sequencing.The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates.Clustering single cells: a review of approaches on high-and low-depth single-cell RNA-seq data.SIDR: simultaneous isolation and parallel sequencing of genomic DNA and total RNA from single cells.Insights into human intrinsically disordered proteins from their gene expression profile.Troy+ brain stem cells cycle through quiescence and regulate their number by sensing niche occupancy.β-Cells are not uniform after all-Novel insights into molecular heterogeneity of insulin-secreting cells.Single-cell sequencing reveals dissociation-induced gene expression in tissue subpopulations.Whole-Body Single-Cell Sequencing Reveals Transcriptional Domains in the Annelid Larval Body.Quartz-Seq2: a high-throughput single-cell RNA-sequencing method that effectively uses limited sequence reads.Identity and dynamics of mammary stem cells during branching morphogenesis.Single-Cell Genomics Unravels Brain Cell-Type Complexity.Characterizing the replicability of cell types defined by single cell RNA-sequencing data using MetaNeighbor.Cell type discovery using single-cell transcriptomics: implications for ontological representation.Single-cell analyses of human islet cells reveal de-differentiation signatures.Heterogeneity and cell fate flux in single human pancreatic islet cells.The role of beta cell heterogeneity in islet function and insulin release.Gene expression profiling of periodontitis-affected gingival tissue by spatial transcriptomics.Single-cell transcriptomics reveal the dynamic of haematopoietic stem cell production in the aorta.Batch effects in single-cell RNA-sequencing data are corrected by matching mutual nearest neighborsATRX, DAXX or MEN1 mutant pancreatic neuroendocrine tumors are a distinct alpha-cell signature subgroupSingle cell RNA sequencing of human liver reveals distinct intrahepatic macrophage populationsEpigenetic Control of Endocrine Pancreas Differentiation : Current Knowledge and Future PerspectivesLineage dynamics of murine pancreatic development at single-cell resolution
P2860
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P2860
A Single-Cell Transcriptome Atlas of the Human Pancreas.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 28 September 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A Single-Cell Transcriptome Atlas of the Human Pancreas.
@en
A Single-Cell Transcriptome Atlas of the Human Pancreas.
@nl
type
label
A Single-Cell Transcriptome Atlas of the Human Pancreas.
@en
A Single-Cell Transcriptome Atlas of the Human Pancreas.
@nl
prefLabel
A Single-Cell Transcriptome Atlas of the Human Pancreas.
@en
A Single-Cell Transcriptome Atlas of the Human Pancreas.
@nl
P2093
P2860
P1433
P1476
A Single-Cell Transcriptome Atlas of the Human Pancreas.
@en
P2093
Dominic Grün
Eelco J P de Koning
Erik Jansen
Francoise Carlotti
Gitanjali Dharmadhikari
Leon van Gurp
Marten A Engelse
Mauro J Muraro
Nathalie Groen
Tim Dielen
P2860
P304
385-394.e3
P356
10.1016/J.CELS.2016.09.002
P577
2016-09-28T00:00:00Z