Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework.
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Radical-mediated enzymatic carbon chain fragmentation-recombinationMechanistic and functional versatility of radical SAM enzymesCatalytic Promiscuity of the Radical S-adenosyl-L-methionine Enzyme NosLThiopeptide antibiotics: retrospective and recent advancesRadical SAM-mediated methylation reactionsRadical-mediated enzymatic methylation: a tale of two SAMSThioFinder: a web-based tool for the identification of thiopeptide gene clusters in DNA sequencesMining of the pyrrolamide antibiotics analogs in Streptomyces netropsis reveals the amidohydrolase-dependent "iterative strategy" underlying the pyrrole polymerizationThe phosphopantetheinyl transferases: catalysis of a post-translational modification crucial for lifeComparative genomics and transcriptomics of Propionibacterium acnesA simple reverse genetics approach to elucidating the biosynthetic pathway of nocathiacin.Identification and analysis of the biosynthetic gene cluster encoding the thiopeptide antibiotic cyclothiazomycin in Streptomyces hygroscopicus 10-22.Emerging themes in radical SAM chemistryManipulation of thiocillin variants by prepeptide gene replacement: structure, conformation, and activity of heterocycle substitution mutants.Natural products version 2.0: connecting genes to molecules.Genetic interception and structural characterization of thiopeptide cyclization precursors from Bacillus cereus.Thiazolyl peptide antibiotic biosynthesis: a cascade of post-translational modifications on ribosomal nascent proteins.Genome mining for ribosomally synthesized natural productsThiazole/oxazole-modified microcins: complex natural products from ribosomal templatesA systematic analysis of biosynthetic gene clusters in the human microbiome reveals a common family of antibiotics.YcaO domains use ATP to activate amide backbones during peptide cyclodehydrations.Ribosomally synthesized and post-translationally modified peptide natural products: overview and recommendations for a universal nomenclature.Genome shuffling and ribosome engineering of Streptomyces actuosus for high-yield nosiheptide production.Identification of an Auxiliary Leader Peptide-Binding Protein Required for Azoline Formation in Ribosomal Natural Products.Characterization of NocL involved in thiopeptide nocathiacin I biosynthesis: a [4Fe-4S] cluster and the catalysis of a radical S-adenosylmethionine enzyme.Peptidomimetics via modifications of amino acids and peptide bonds.Identification of the thiazolyl peptide GE37468 gene cluster from Streptomyces ATCC 55365 and heterologous expression in Streptomyces lividans.Complex biotransformations catalyzed by radical S-adenosylmethionine enzymes.Structure-based Mechanistic Insights into Terminal Amide Synthase in Nosiheptide-Represented Thiopeptides BiosynthesisElucidating and engineering thiopeptide biosynthesis.Microbial and biochemical basis of a Fusarium wilt-suppressive soilNew Insights into the Biosynthetic Logic of Ribosomally Synthesized and Post-translationally Modified Peptide Natural Products.Revealing nature's synthetic potential through the study of ribosomal natural product biosynthesis.Follow the leader: the use of leader peptides to guide natural product biosynthesis.Radical new paradigm for heme degradation in Escherichia coli O157:H7.An α/β-hydrolase fold protein in the biosynthesis of thiostrepton exhibits a dual activity for endopeptidyl hydrolysis and epoxide ring opening/macrocyclization.Recent advances in thiopeptide antibiotic biosynthesis.Radical S-adenosylmethionine enzymes.Radical S-adenosylmethionine enzymes: mechanism, control and function.Biosynthesis of thiopeptide antibiotics and their pathway engineering.
P2860
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P2860
Nosiheptide biosynthesis featuring a unique indole side ring formation on the characteristic thiopeptide framework.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Nosiheptide biosynthesis featu ...... eristic thiopeptide framework.
@en
Nosiheptide biosynthesis featu ...... eristic thiopeptide framework.
@nl
type
label
Nosiheptide biosynthesis featu ...... eristic thiopeptide framework.
@en
Nosiheptide biosynthesis featu ...... eristic thiopeptide framework.
@nl
prefLabel
Nosiheptide biosynthesis featu ...... eristic thiopeptide framework.
@en
Nosiheptide biosynthesis featu ...... eristic thiopeptide framework.
@nl
P2093
P2860
P921
P356
P1433
P1476
Nosiheptide biosynthesis featu ...... eristic thiopeptide framework.
@en
P2093
Evelyn Wendt-Pienkowski
Gongli Tang
Rijing Liao
P2860
P304
P356
10.1021/CB900133X
P577
2009-10-01T00:00:00Z