Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.

Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.

Item
http://www.wikidata.org/entity/Q37395719
Long-Term Engraftment and Fetal Globin Induction upon BCL11A Gene Editing in Bone-Marrow-Derived CD34+ Hematopoietic Stem and Progenitor Cells.Emerging cellular and gene therapies for congenital anemias.Gene Therapy for β-Hemoglobinopathies.Strict in vivo specificity of the Bcl11a erythroid enhancer.Pharmacological and molecular approaches for the treatment of β-hemoglobin disorders.Recent progress in understanding and manipulating haemoglobin switching for the haemoglobinopathies.A Nonhuman Primate Transplantation Model to Evaluate Hematopoietic Stem Cell Gene Editing Strategies for β-Hemoglobinopathies.Concise Review: Epigenetic Regulation of Hematopoiesis: Biological Insights and Therapeutic Applications.Rapid and Sensitive Assessment of Globin Chains for Gene and Cell Therapy of Hemoglobinopathies.Emerging Therapies.Short-hairpin RNA against aberrant HBB[IVSI-110(G>A)] mRNA restores β-globin levels in a novel cell model and acts as mono- and combination therapy for β-thalassemia in primary hematopoietic stem cells.DROSHA Knockout Leads to Enhancement of Viral Titers for Vectors Encoding miRNA-Adapted shRNAsTRIAMF: A New Method for Delivery of Cas9 Ribonucleoprotein Complex to Human Hematopoietic Stem CellsDisruption of the BCL11A Erythroid Enhancer Reactivates Fetal Hemoglobin in Erythroid Cells of Patients with β-Thalassemia MajorGene Therapy for Hemoglobinopathies
P2860

Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.

Item
http://www.wikidata.org/entity/Q37395719
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 06 September 2016
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
@en
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
@nl
type
label
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
@en
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
@nl
prefLabel
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
@en
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
@nl
P1433
P1476
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932
P356
P1433
P1476
Lineage-specific BCL11A knockdown circumvents toxicities and reverses sickle phenotype.
@en
P2093
P2860
P304
P31
P356
P407
P433
P478
P50
P577
P698
P932