HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity
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SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by NefHIV-1 Nef promotes infection by excluding SERINC5 from virion incorporationHIV Genome-Wide Protein Associations: a Review of 30 Years of ResearchSERINC5 protein inhibits HIV-1 fusion pore formation by promoting functional inactivation of envelope glycoproteins.In vivo analysis of Nef's role in HIV-1 replication, systemic T cell activation and CD4(+) T cell loss.The Antagonism of HIV-1 Nef to SERINC5 Particle Infectivity Restriction Involves the Counteraction of Virion-Associated Pools of the Restriction Factor.The Nef-like effect of murine leukemia virus glycosylated gag on HIV-1 infectivity is mediated by its cytoplasmic domain and depends on the AP-2 adaptor complex.The activity of Nef on HIV-1 infectivityEffect of HIV-1 Env on SERINC5 AntagonismThe host-cell restriction factor SERINC5 restricts HIV-1 infectivity without altering the lipid composition and organization of viral particles.Identification of SERINC5-001 as the Predominant Spliced Isoform for HIV-1 Restriction.The Potency of Nef-Mediated SERINC5 Antagonism Correlates with the Prevalence of Primate Lentiviruses in the Wild.Spotlight on HIV-1 Nef: SERINC3 and SERINC5 Identified as Restriction Factors Antagonized by the Pathogenesis Factor.HIV: Antiviral action countered by Nef.Localization to detergent-resistant membranes and HIV-1 core entry inhibition correlate with HIV-1 restriction by SERINC5.A Long Cytoplasmic Loop Governs the Sensitivity of the Anti-viral Host Protein SERINC5 to HIV-1 Nef.SERINC as a Restriction Factor to Inhibit Viral Infectivity and the Interaction with HIV.Inhibiting the Ins and Outs of HIV Replication: Cell-Intrinsic Antiretroviral Restrictions at the Plasma Membrane.La mystérieuse cible de la protéine virale Nef identifiée : les protéines SERINC3 et SERINC5
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P2860
HIV-1 Nef responsiveness is determined by Env variable regions involved in trimer association and correlates with neutralization sensitivity
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 October 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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name
HIV-1 Nef responsiveness is de ...... ith neutralization sensitivity
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HIV-1 Nef responsiveness is de ...... th neutralization sensitivity.
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type
label
HIV-1 Nef responsiveness is de ...... ith neutralization sensitivity
@en
HIV-1 Nef responsiveness is de ...... th neutralization sensitivity.
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HIV-1 Nef responsiveness is de ...... ith neutralization sensitivity
@en
HIV-1 Nef responsiveness is de ...... th neutralization sensitivity.
@nl
P2860
P1433
P1476
HIV-1 Nef responsiveness is de ...... ith neutralization sensitivity
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P2093
Heinrich Göttlinger
Yoshiko Usami
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P304
P356
10.1016/J.CELREP.2013.09.028
P577
2013-10-24T00:00:00Z