Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
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A new paradigm for mechanobiological mechanisms in tumor metastasisInternal strain drives spontaneous periodic buckling in collagen and regulates remodeling.Mechanical strain stabilizes reconstituted collagen fibrils against enzymatic degradation by mammalian collagenase matrix metalloproteinase 8 (MMP-8)Molecular simulations predict novel collagen conformations during cross-link loading.Small-angle light scattering to detect strain-directed collagen degradation in native tissue.Molecular mechanochemistry: low force switch slows enzymatic cleavage of human type I collagen monomer.Mechanical load induces a 100-fold increase in the rate of collagen proteolysis by MMP-1.Adaptive Remodeling of Achilles Tendon: A Multi-scale Computational ModelMicromechanical Modeling Study of Mechanical Inhibition of Enzymatic Degradation of Collagen Tissues.Mechanical Forces Accelerate Collagen Digestion by Bacterial Collagenase in Lung Tissue Strips.Molecular crowding of collagen: a pathway to produce highly-organized collagenous structuresA conceptual framework for computational models of Achilles tendon homeostasis.Mechanistic micro-structural theory of soft tissues growth and remodeling: tissues with unidirectional fibers.Growth and Remodeling of Load-Bearing Biological Soft Tissues.Conformational dynamics accompanying the proteolytic degradation of trimeric collagen I by collagenases.Glycation cross-linking induced mechanical-enzymatic cleavage of microscale tendon fibers.Highly sensitive single-fibril erosion assay demonstrates mechanochemical switch in native collagen fibrils.Chain registry and load-dependent conformational dynamics of collagenMET Activation and Physical Dynamics of the Metastatic Process: The Paradigm of Cancers of Unknown Primary Origin.Probing collagen/enzyme mechanochemistry in native tissue with dynamic, enzyme-induced creep.A physically motivated constitutive model for cell-mediated compaction and collagen remodeling in soft tissues.Effect of Dynamic Changes in Anterior Cruciate Ligament In Situ Graft Force on the Biological Healing Response of the Graft-Tunnel Interface.Efficient computational simulation of actin stress fiber remodeling.Modeling the impact of scaffold architecture and mechanical loading on collagen turnover in engineered cardiovascular tissues.
P2860
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P2860
Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
@en
Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
@nl
type
label
Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
@en
Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
@nl
prefLabel
Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
@en
Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
@nl
P2093
P2860
P356
P1476
Deformation-dependent enzyme mechanokinetic cleavage of type I collagen.
@en
P2093
Jonathan W Bourne
Karla E-K Wyatt
Peter A Torzilli
P2860
P304
P356
10.1115/1.3078177
P577
2009-05-01T00:00:00Z