The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans.
about
The crucial impact of lysosomes in aging and longevityAutophagy and agingEaten alive: novel insights into autophagy from multicellular model systemsIntestinal Autophagy Improves Healthspan and Longevity in C. elegans during Dietary RestrictionDLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegansGraded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome PathwayDAF-16 and TCER-1 Facilitate Adaptation to Germline Loss by Restoring Lipid Homeostasis and Repressing Reproductive Physiology in C. elegansAutophagy and modular restructuring of metabolism control germline tumor differentiation and proliferation in C. elegansGermline signals deploy NHR-49 to modulate fatty-acid β-oxidation and desaturation in somatic tissues of C. elegansModulation of the maladaptive stress response to manage diseases of protein foldingTFEB at a glanceMechanisms of aging-related proteinopathies in Caenorhabditis elegansGuidelines for monitoring autophagy in Caenorhabditis elegansTranscriptional and epigenetic regulation of autophagy in agingMediation of organismal aging and somatic proteostasis by the germlineEssential role for autophagy in life span extensionAn Evolutionarily Conserved PLC-PKD-TFEB Pathway for Host DefenseC. elegans S6K Mutants Require a Creatine-Kinase-like Effector for Lifespan ExtensionTransaldolase inhibition impairs mitochondrial respiration and induces a starvation-like longevity response in Caenorhabditis elegans.Uncoupling the Trade-Off between Somatic Proteostasis and Reproduction in Caenorhabditis elegans Models of Polyglutamine Diseases.Lysosomal adaptation: how the lysosome responds to external cuesControl of mitochondrial integrity in ageing and diseaseNovel roles for the MiTF/TFE family of transcription factors in organelle biogenesis, nutrient sensing, and energy homeostasisIntegrin-linked kinase modulates longevity and thermotolerance in C. elegans through neuronal control of HSF-1.Innate host defense requires TFEB-mediated transcription of cytoprotective and antimicrobial genesThe TRiC/CCT chaperone is implicated in Alzheimer's disease based on patient GWAS and an RNAi screen in Aβ-expressing Caenorhabditis elegans.Genome-wide screen identifies signaling pathways that regulate autophagy during Caenorhabditis elegans developmentThe paradox of mitochondrial dysfunction and extended longevity.Metabolic control of autophagyLysosome: regulator of lipid degradation pathways.AMPK at the nexus of energetics and aging.Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagyMitochondrial maintenance failure in aging and role of sexual dimorphism.The unpredictability of prolonged activation of stress response pathways.Tissue-specific transcriptomics and proteomics of a filarial nematode and its Wolbachia endosymbiont.Ectopic fat deposition contributes to age-associated pathology in Caenorhabditis elegans.ESCRT-Dependent Cell Death in a Caenorhabditis elegans Model of the Lysosomal Storage Disorder Mucolipidosis Type IV.Mondo complexes regulate TFEB via TOR inhibition to promote longevity in response to gonadal signalsNuclear hormone receptors as mediators of metabolic adaptability following reproductive perturbations.Drosophila Mitf regulates the V-ATPase and the lysosomal-autophagic pathway.
P2860
Q26749118-0094474A-EA12-4A6E-AFA0-E946D5520793Q26853625-D1FE79D1-35EA-41B7-AFB3-AD4D99EE1A01Q27005828-73317E09-F1A6-4DDA-80A8-7D0F6F32A917Q27308697-CF8C559A-6D9B-4CE1-BC59-B8B459F225B2Q27308709-8F3E0627-6858-4150-8735-0883A0E7CF36Q27309148-F3573026-81DC-4AF6-A86F-860F48028934Q27309247-7B40CDCA-4DFF-46CE-9FB4-E414003BC9C1Q27311265-32680340-2AFE-4E32-A293-F01FA8F83C73Q27311639-4F270545-5D97-4216-B904-A109668F97CFQ27313626-FE7958B3-6C9F-4A38-AB10-EB0CDA1DD512Q28074375-35E5B7FA-C629-4A2D-BF3F-3A74996459B0Q28077338-84826308-3E5C-46CB-9B07-519D3098CF37Q28082233-874DB62E-6756-4CEB-8943-DCFFFC4233BBQ28083637-AB3BDE19-916F-42AC-9176-18A774321FEDQ28084311-E4611C8B-813F-4950-BFBD-BCE5FED804FAQ28085050-08D76FE9-3090-4CD3-9AE8-D3D81912C020Q28508861-5830E915-05A7-4FCE-87BE-0A86E57177D3Q28601083-D1A93974-4CDD-4721-9214-BF856E2D3080Q33558886-D260E3F6-E54E-478A-AF31-0F6BA2B2D36FQ33615396-E1479137-D612-4E16-BCB0-0DE66D80DB68Q33653699-2BB71038-BE18-4335-9640-9B776FC7C098Q33655966-0E017861-3339-4C34-BD97-F4DC36AAD4CDQ33756641-BF50D3EC-79EA-4BC5-89B2-50E2F411465BQ33762944-A7522AD1-ABF7-4B8B-B771-5469913CD2DBQ33924772-91FD22D7-6012-4AD6-8B59-462D5B634F58Q33982824-E5F23B9B-0A72-40BF-9C45-C4FF781E4287Q34342556-94373D15-8E34-40FE-BE92-AD635F8C772CQ34413560-898B1854-ECF0-4584-937B-2F3A51BD41A3Q34452291-ADCF662C-F7C1-475E-A7F0-B859025B95CDQ34585737-1547377C-B7F4-4924-8094-25BB32482706Q34871517-0CA946CB-C7D8-47F0-A433-F1A8BB630543Q35215643-9352543B-0D69-42E9-8433-2D6B97288BFEQ35538600-7CFAA240-7A9F-4A27-A086-87E42376E94BQ35771415-41717B06-23F3-473D-A664-D19B0A334F6EQ35838815-3E550168-0C84-4FED-87C8-91951002F1F2Q36203731-1DCBBAE9-544A-4C78-945E-813D91084E7DQ36677308-12DBB4B6-E042-452D-A5AA-A799E0D85120Q36719136-0B919444-9BA0-47BF-BA3C-FB6A5DF1446FQ36722812-45E52AAF-5763-458A-BA37-927B0A11FB5BQ36810805-3D16AC42-E868-4D57-8B9A-E252E8B7E44C
P2860
The TFEB orthologue HLH-30 regulates autophagy and modulates longevity in Caenorhabditis elegans.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2013
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The TFEB orthologue HLH-30 reg ...... ity in Caenorhabditis elegans.
@en
The TFEB orthologue HLH-30 reg ...... ity in Caenorhabditis elegans.
@nl
type
label
The TFEB orthologue HLH-30 reg ...... ity in Caenorhabditis elegans.
@en
The TFEB orthologue HLH-30 reg ...... ity in Caenorhabditis elegans.
@nl
prefLabel
The TFEB orthologue HLH-30 reg ...... ity in Caenorhabditis elegans.
@en
The TFEB orthologue HLH-30 reg ...... ity in Caenorhabditis elegans.
@nl
P2093
P2860
P50
P356
P1476
The TFEB orthologue HLH-30 reg ...... ity in Caenorhabditis elegans.
@en
P2093
Andrew Dillin
Andrew E Davis
Binnan Ong
C Daniel De Magalhaes Filho
Chu-Chiao Chu
Jessica T Chang
Malene Hansen
Philip R McQuary
Sara Gelino
P2860
P2888
P356
10.1038/NCOMMS3267
P407
P577
2013-01-01T00:00:00Z