The dynamics of adaptation on correlated fitness landscapes
about
Predictability of evolutionary trajectories in fitness landscapesThe causes of epistasisPrevalence of epistasis in the evolution of influenza A surface proteinsExperimental evolution with E. coli in diverse resource environments. I. Fluctuating environments promote divergence of replicate populations.Inferring fitness landscapes by regression produces biased estimates of epistasis.Young proteins experience more variable selection pressures than old proteins.Replaying the tape of life: quantification of the predictability of evolution.Changes in selective effects over time facilitate turnover of enhancer sequences.The environment affects epistatic interactions to alter the topology of an empirical fitness landscapeEpistasis increases the rate of conditionally neutral substitution in an adapting population.The impact of macroscopic epistasis on long-term evolutionary dynamicsQuantifying the similarity of monotonic trajectories in rough and smooth fitness landscapes.Mapping the fitness landscape of gene expression uncovers the cause of antagonism and sign epistasis between adaptive mutations.Adaptation of a cyanobacterium to a biochemically rich environment in experimental evolution as an initial step toward a chloroplast-like stateBackbones of evolutionary history test biodiversity theory for microbes.Stickbreaking: a novel fitness landscape model that harbors epistasis and is consistent with commonly observed patterns of adaptive evolution.The genetic consequences of selection in natural populations.Exploiting the Adaptation Dynamics to Predict the Distribution of Beneficial Fitness Effects.Theory of prokaryotic genome evolutionIdentification of the potentiating mutations and synergistic epistasis that enabled the evolution of inter-species cooperation.Benefit of transferred mutations is better predicted by the fitness of recipients than by their ecological or genetic relatednessHow Good Are Statistical Models at Approximating Complex Fitness Landscapes?Mechanisms and selection of evolvability: experimental evidence.Microbial evolution. Global epistasis makes adaptation predictable despite sequence-level stochasticity.Diminishing returns epistasis among beneficial mutations decelerates adaptation.The strength of genetic interactions scales weakly with mutational effects.Evolution of new regulatory functions on biophysically realistic fitness landscapes.Adaptation in tunably rugged fitness landscapes: the rough Mount Fuji model.The dynamics of adapting, unregulated populations and a modified fundamental theorem.Selection Limits to Adaptive Walks on Correlated Landscapes.The peaks and geometry of fitness landscapes.Detecting epistasis from an ensemble of adapting populations.Introduction to focus issue: genetic interactions.Genetic background affects epistatic interactions between two beneficial mutations.Negative epistasis between beneficial mutations in an evolving bacterial population.Long-term dynamics of adaptation in asexual populations.On the findability of genotypes.Parallel emergence of negative epistasis across experimental lineages.The dynamics of molecular evolution over 60,000 generations.Beneficial mutation-selection dynamics in finite asexual populations: a free boundary approach.
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The dynamics of adaptation on correlated fitness landscapes
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 26 October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The dynamics of adaptation on correlated fitness landscapes
@en
The dynamics of adaptation on correlated fitness landscapes.
@nl
type
label
The dynamics of adaptation on correlated fitness landscapes
@en
The dynamics of adaptation on correlated fitness landscapes.
@nl
prefLabel
The dynamics of adaptation on correlated fitness landscapes
@en
The dynamics of adaptation on correlated fitness landscapes.
@nl
P2860
P356
P1476
The dynamics of adaptation on correlated fitness landscapes
@en
P2093
Gasper Tkacik
Sergey Kryazhimskiy
P2860
P304
18638-18643
P356
10.1073/PNAS.0905497106
P407
P577
2009-10-26T00:00:00Z