Single application of a CB1 receptor antagonist rapidly following head injury prevents long-term hyperexcitability in a rat model
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Epilepsy related to traumatic brain injury.Cannabinoids and Epilepsy.Pursuing paradoxical proconvulsant prophylaxis for epileptogenesisStatistical parametric mapping reveals regional alterations in cannabinoid CB1 receptor distribution and G-protein activation in the 3D reconstructed epileptic rat brain.The potential of antiseizure drugs and agents that act on novel molecular targets as antiepileptogenic treatments.ADC mapping and T1-weighted signal changes on post-injury MRI predict seizure susceptibility after experimental traumatic brain injury.Dentate cannabinoid-sensitive interneurons undergo unique and selective strengthening of mutual synaptic inhibition in experimental epilepsy.Astrocytic expression of cannabinoid type 1 receptor in rat and human sclerotic hippocampi.The effect of the cannabinoid-receptor antagonist, SR141716, on the early stage of kainate-induced epileptogenesis in the adult rat.Redistribution of CB1 cannabinoid receptors in the acute and chronic phases of pilocarpine-induced epilepsyPrevention or modification of epileptogenesis after brain insults: experimental approaches and translational research.Cannabinoid receptor 1 blockade protects human retinal pigment epithelial cells from oxidative injury.Past and present definitions of epileptogenesis and its biomarkers.Therapeutic approaches to epileptogenesis--hope on the horizon.Marijuana, endocannabinoids, and epilepsy: potential and challenges for improved therapeutic intervention.Neural circuit mechanisms of post-traumatic epilepsy.The potential role of cannabinoids in epilepsy treatment.Enhanced Dentate Neurogenesis after Brain Injury Undermines Long-Term Neurogenic Potential and Promotes Seizure Susceptibility.Therapeutic effects of cannabinoids in animal models of seizures, epilepsy, epileptogenesis, and epilepsy-related neuroprotection.CB1 receptor antagonism impairs the induction of epileptiform activity by group I metabotropic glutamate receptor activation.Posttraumatic Epilepsy: What's Contusion Got to Do With It?Do proconvulsants modify or halt epileptogenesis? Pentylenetetrazole is ineffective in two rat models of temporal lobe epilepsy.Effects of Human ES-Derived Neural Stem Cell Transplantation and Kindling in a Rat Model of Traumatic Brain Injury.Disease-modifying effects of RHC80267 and JZL184 in a pilocarpine mouse model of temporal lobe epilepsy.
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P2860
Single application of a CB1 receptor antagonist rapidly following head injury prevents long-term hyperexcitability in a rat model
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 15 April 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Single application of a CB1 re ...... perexcitability in a rat model
@en
Single application of a CB1 re ...... erexcitability in a rat model.
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type
label
Single application of a CB1 re ...... perexcitability in a rat model
@en
Single application of a CB1 re ...... erexcitability in a rat model.
@nl
prefLabel
Single application of a CB1 re ...... perexcitability in a rat model
@en
Single application of a CB1 re ...... erexcitability in a rat model.
@nl
P2093
P2860
P1433
P1476
Single application of a CB1 re ...... perexcitability in a rat model
@en
P2093
Ivan Soltesz
Julio Echegoyen
Robert J Morgan
P2860
P304
P356
10.1016/J.EPLEPSYRES.2009.02.019
P577
2009-04-15T00:00:00Z