Synthesis and evaluation in monkey of [(18)F]4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX): a promising radioligand for PET imaging of brain metabotropic glutamate receptor 1 (mGluR1)
about
[carbonyl-11C]4-Fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([11C]FIMX) is an effective radioligand for PET imaging of metabotropic glutamate receptor 1 (mGluR1) in monkey brain.Measuring specific receptor binding of a PET radioligand in human brain without pharmacological blockade: The genomic plot.The PET Radioligand 18F-FIMX Images and Quantifies Metabotropic Glutamate Receptor 1 in Proportion to the Regional Density of Its Gene Transcript in Human Brain.[(18)F]6-fluoro-3,4-dihydroxy-L-phenylalanine--recent modern syntheses for an elusive radiotracer.Considerations in the Development of Reversibly Binding PET Radioligands for Brain Imaging.Synthesis and evaluation of N-(methylthiophenyl)picolinamide derivatives as PET radioligands for metabotropic glutamate receptor subtype 4.Crystal Structures of Diaryliodonium Fluorides and Their Implications for Fluorination Mechanisms.Development of PET and SPECT probes for glutamate receptors.Arylation with Diaryliodonium Salts.
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P2860
Synthesis and evaluation in monkey of [(18)F]4-fluoro-N-methyl-N-(4-(6-(methylamino)pyrimidin-4-yl)thiazol-2-yl)benzamide ([(18)F]FIMX): a promising radioligand for PET imaging of brain metabotropic glutamate receptor 1 (mGluR1)
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Synthesis and evaluation in monkey of [
@nl
Synthesis and evaluation in mo ...... glutamate receptor 1 (mGluR1)
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type
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Synthesis and evaluation in monkey of [
@nl
Synthesis and evaluation in mo ...... glutamate receptor 1 (mGluR1)
@en
prefLabel
Synthesis and evaluation in monkey of [
@nl
Synthesis and evaluation in mo ...... glutamate receptor 1 (mGluR1)
@en
P2093
P2860
P356
P1476
Synthesis and evaluation in mo ...... glutamate receptor 1 (mGluR1)
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P2093
Alicia E Woock
Robert B Innis
Robert L Gladding
Sami S Zoghbi
Victor W Pike
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P304
P356
10.1021/JM4012017
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P577
2013-11-07T00:00:00Z