Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha (SDF-1alpha) and SDF-1beta are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage.
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Interaction of human dipeptidyl peptidase IV and human immunodeficiency virus type-1 transcription transactivator in Sf9 cellsSequence, purification, and cloning of an intracellular serine protease, quiescent cell proline dipeptidaseNeuropeptide Y, B-type natriuretic peptide, substance P and peptide YY are novel substrates of fibroblast activation protein-αStromal cell-derived factors 1alpha and 1beta, inflammatory protein-10 and interferon-inducible T cell chemo-attractant are novel substrates of dipeptidyl peptidase 8Dipeptidyl peptidase IV activity and/or structure homologs: contributing factors in the pathogenesis of rheumatoid arthritis?Incretin-Based Therapies for Diabetic Complications: Basic Mechanisms and Clinical EvidenceDiversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesRegulation of Chemokine Activity - A Focus on the Role of Dipeptidyl Peptidase IV/CD26Mononuclear cells and vascular repair in HHTThe HIV-1 gp120 inhibits the binding of adenosine deaminase to CD26 by a mechanism modulated by CD4 and CXCR4 expressionKinetic investigation of chemokine truncation by CD26/dipeptidyl peptidase IV reveals a striking selectivity within the chemokine familyNatural truncation of the chemokine MIP-1 beta /CCL4 affects receptor specificity but not anti-HIV-1 activityComodulation of CXCR4 and CD26 in human lymphocytesTruncation of macrophage-derived chemokine by CD26/ dipeptidyl-peptidase IV beyond its predicted cleavage site affects chemotactic activity and CC chemokine receptor 4 interactionThe CXCR4 antagonist AMD3100 efficiently inhibits cell-surface-expressed human immunodeficiency virus type 1 envelope-induced apoptosisESkine, a novel beta-chemokine, is differentially spliced to produce secretable and nuclear targeted isoformsEnhanced anti-HIV-1 activity of CC-chemokine LD78β, a non-allelic variant of MIP-1α/LD78αRapid inactivation of stromal cell-derived factor-1 by cathepsin G associated with lymphocytes.Genetic ablation or pharmacological blockade of dipeptidyl peptidase IV does not impact T cell-dependent immune responses.Anti-HIV activity in cervical-vaginal secretions from HIV-positive and -negative women correlate with innate antimicrobial levels and IgG antibodiesParamyxovirus replication and pathogenesis. Reverse genetics transforms understanding.Paramyxovirus reverse genetics is coming of age.Uric acid inhibition of dipeptidyl peptidase IV in vitro is dependent on the intracellular formation of triuretIncrease of CD26/dipeptidyl peptidase IV expression on human gingival fibroblasts upon stimulation with cytokines and bacterial components.Apigenin and its impact on gastrointestinal cancers.Dipeptidyl-peptidase IV from bench to bedside: an update on structural properties, functions, and clinical aspects of the enzyme DPP IV.Differential Expression and Enzymatic Activity of DPPIV/CD26 Affects Migration Ability of Cervical Carcinoma Cells.The many facets of SDF-1alpha, CXCR4 agonists and antagonists on hematopoietic progenitor cells.Inhibition of CD26/DPP-IV enhances donor muscle cell engraftment and stimulates sustained donor cell proliferationLocation, movement and survival: the role of chemokines in haematopoiesis and malignancy.A role for dipeptidyl peptidase IV in suppressing the malignant phenotype of melanocytic cells.Loss of CD26 protease activity in recipient mice during hematopoietic stem cell transplantation results in improved transplant efficiency.Clinical utilization of chemokines to combat cancer: the double-edged sword.Inhibition of dipeptidylpeptidase IV activity as a therapy of type 2 diabetes.Dipeptidyl peptidase IV inhibition does not adversely affect immune or virological status in HIV infected men and women: a pilot safety study.Multiple roles for chemokines in the pathogenesis of SIV infectionSoluble complexes of regulated upon activation, normal T cells expressed and secreted (RANTES) and glycosaminoglycans suppress HIV-1 infection but do not induce Ca(2+) signaling.Glypican-3-mediated inhibition of CD26 by TFPI: a novel mechanism in hematopoietic stem cell homing and maintenance.Dipeptidyl Peptidase-4 Inhibitor Increases Vascular Leakage in Retina through VE-cadherin Phosphorylation.Natural nitration of CXCL12 reduces its signaling capacity and chemotactic activity in vitro and abrogates intra-articular lymphocyte recruitment in vivo.
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Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha (SDF-1alpha) and SDF-1beta are abolished by CD26/dipeptidyl peptidase IV-mediated cleavage.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on May 1998
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Anti-HIV-1 and chemotactic act ...... eptidase IV-mediated cleavage.
@en
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha
@nl
type
label
Anti-HIV-1 and chemotactic act ...... eptidase IV-mediated cleavage.
@en
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha
@nl
prefLabel
Anti-HIV-1 and chemotactic act ...... eptidase IV-mediated cleavage.
@en
Anti-HIV-1 and chemotactic activities of human stromal cell-derived factor 1alpha
@nl
P2093
P2860
P356
P1476
Anti-HIV-1 and chemotactic act ...... peptidase IV-mediated cleavage
@en
P2093
C Morimoto
E E Nakayama
P2860
P304
P356
10.1073/PNAS.95.11.6331
P407
P577
1998-05-01T00:00:00Z