APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma. - Wikidata - wikimedia - TriplyDB

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

http://www.wikidata.org/entity/Q37402303

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Breaking bad: The mutagenic effect of DNA repair AID/APOBEC deaminases and cancer Molecular mechanism and clinical impact of APOBEC3B-catalyzed mutagenesis in breast cancer APOBEC3B, a molecular driver of mutagenesis in human cancers.Structural determinants of APOBEC3B non-catalytic domain for molecular assembly and catalytic regulation Repair of naturally occurring mismatches can induce mutations in flanking DNA.Association between targeted somatic mutation (TSM) signatures and HGS-OvCa progression Identification of genomic alterations in pancreatic cancer using array-based comparative genomic hybridization.Human papillomavirus E6 triggers upregulation of the antiviral and cancer genomic DNA deaminase APOBEC3B APOBEC3B expression in breast cancer reflects cellular proliferation, while a deletion polymorphism is associated with immune activation.Characterization of the Catalytic Domain of Human APOBEC3B and the Critical Structural Role for a Conserved Methionine.APOBEC Enzymes: Mutagenic Fuel for Cancer Evolution and Heterogeneity.TP53 mutations, tetraploidy and homologous recombination repair defects in early stage high-grade serous ovarian cancer Mutation Processes in 293-Based Clones Overexpressing the DNA Cytosine Deaminase APOBEC3B.Association of Hepatitis B Virus Covalently Closed Circular DNA and Human APOBEC3B in Hepatitis B Virus-Related Hepatocellular Carcinoma.APOBEC family mutational signatures are associated with poor prognosis translocations in multiple myeloma AID/APOBEC-network reconstruction identifies pathways associated with survival in ovarian cancer.An APOBEC3A hypermutation signature is distinguishable from the signature of background mutagenesis by APOBEC3B in human cancers APOBEC3B-Mediated Cytidine Deamination Is Required for Estrogen Receptor Action in Breast Cancer.DNA cytosine and methylcytosine deamination by APOBEC3B: enhancing methylcytosine deamination by engineering APOBEC3B.Expression of APOBEC3B mRNA in Primary Breast Cancer of Japanese Women.The PKC/NF-κB signaling pathway induces APOBEC3B expression in multiple human cancers.Progressive APOBEC3B mRNA expression in distant breast cancer metastases.Transcriptional regulation of APOBEC3 antiviral immunity through the CBF-β/RUNX axis.Crystal Structure of the DNA Deaminase APOBEC3B Catalytic Domain.A common variant in MTHFR influences response to chemoradiotherapy and recurrence of rectal cancer.Integrative genomic analysis reveals functional diversification of APOBEC gene family in breast cancer.APOBEC3A damages the cellular genome during DNA replication Independent validation of a mathematical genomic model for survival of glioma patients.Nuclear Magnetic Resonance Structure of the APOBEC3B Catalytic Domain: Structural Basis for Substrate Binding and DNA Deaminase Activity.Activation-Induced Cytidine Deaminase Links Ovulation-Induced Inflammation and Serous Carcinogenesis The DNA cytosine deaminase APOBEC3H haplotype I likely contributes to breast and lung cancer mutagenesis.The DNA cytosine deaminase APOBEC3B promotes tamoxifen resistance in ER-positive breast cancer.APOBEC3B expression in human leptomeninges and meningiomas.Risks at the DNA Replication Fork: Effects upon Carcinogenesis and Tumor Heterogeneity Mechanisms of base substitution mutagenesis in cancer genomes.A Novel Regulator of Activation-Induced Cytidine Deaminase/APOBECs in Immunity and Cancer: Schrödinger's CATalytic Pocket.DNA damage repair machinery and HIV escape from innate immune sensing.Degradation of the cancer genomic DNA deaminase APOBEC3B by SIV Vif Elevated APOBEC3B expression drives a kataegic-like mutation signature and replication stress-related therapeutic vulnerabilities in p53-defective cells.

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APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

http://www.wikidata.org/entity/Q37402303

description

article científic

@ca

article scientifique

@fr

articolo scientifico

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artigo científico

@pt

bilimsel makale

@tr

scientific article published on 23 October 2013

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

@en

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

@nl

type

label

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

@en

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

@nl

prefLabel

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

@en

APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma.

@nl

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0008-5472.CAN-13-1753

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Cancer Research

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APOBEC3B upregulation and genomic mutation patterns in serous ovarian carcinoma

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Ann L Oberg

http://www.w3.org/2001/XMLSchema#string

Anurag Rathore

http://www.w3.org/2001/XMLSchema#string

Brandon Leonard

http://www.w3.org/2001/XMLSchema#string

Craig April

http://www.w3.org/2001/XMLSchema#string

David Bentley

http://www.w3.org/2001/XMLSchema#string

Debra A Bell

http://www.w3.org/2001/XMLSchema#string

Elizabeth M Swisher

http://www.w3.org/2001/XMLSchema#string

Ellen L Goode

http://www.w3.org/2001/XMLSchema#string

Emily K Law

http://www.w3.org/2001/XMLSchema#string

Hugues Sicotte

http://www.w3.org/2001/XMLSchema#string

P2860

APOBEC3 proteins mediate the clearance of foreign DNA from human cells

APOBEC3A and APOBEC3B are potent inhibitors of LTR-retrotransposon function in human cells

The restriction factors of human immunodeficiency virus

Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing

Comprehensive molecular portraits of human breast tumours

Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

Integrated genomic analyses of ovarian carcinoma

Cancer statistics, 2012

APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism

Signatures of mutational processes in human cancer

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7222-7231

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scholarly article

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10.1158/0008-5472.CAN-13-1753

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24

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73

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Rachel Isaksson Vogel

Michael B Burns

Scott H Kaufmann

Matthew J Maurer

Michael Carpenter

Reuben S Harris

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2013-10-23T00:00:00Z

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24154874

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3867573

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