Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis. - Wikidata - wikimedia - TriplyDB

Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis.

Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis.

http://www.wikidata.org/entity/Q37402410

about

Novel Family of Insect Salivary Inhibitors Blocks Contact Pathway Activation by Binding to Polyphosphate, Heparin, and Dextran Sulfate Nitrophorin 2, a factor IX(a)-directed anticoagulant, inhibits arterial thrombosis without impairing haemostasis Serine Protease Inhibitors in Ticks: An Overview of Their Role in Tick Biology and Tick-Borne Pathogen Transmission.Deorphanization and target validation of cross-tick species conserved novel Amblyomma americanum tick saliva protein.Amblyomma americanum tick saliva serine protease inhibitor 6 is a cross-class inhibitor of serine proteases and papain-like cysteine proteases that delays plasma clotting and inhibits platelet aggregation Identification and characterization of Ixodes scapularis antigens that elicit tick immunity using yeast surface display.A factor XIIa inhibitory antibody provides thromboprotection in extracorporeal circulation without increasing bleeding risk.Contact pathway of coagulation and inflammation Evolution, expansion and expression of the Kunitz/BPTI gene family associated with long-term blood feeding in Ixodes Scapularis Tick salivary secretion as a source of antihemostatics.Identification and anticoagulant activity of a novel Kunitz-type protein HA11 from the salivary gland of the tick Hyalomma asiaticum.Factor XIa inhibitors: A review of the patent literature.Tick salivary compounds: their role in modulation of host defences and pathogen transmission Desmolaris, a novel factor XIa anticoagulant from the salivary gland of the vampire bat (Desmodus rotundus) inhibits inflammation and thrombosis in vivo.Anti-aggregatory effect of boswellic acid in high-fat fed rats: involvement of redox and inflammatory cascades.Factor XI and XII as antithrombotic targets.Investigational anticoagulants for hematological conditions: a new generation of therapies.Factor XII: a novel target for safe prevention of thrombosis and inflammation.Factor XII: form determines function.COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke.The Essential Role of Tick Salivary Glands and Saliva in Tick Feeding and Pathogen Transmission.Selective depletion of plasma prekallikrein or coagulation factor XII inhibits thrombosis in mice without increased risk of bleeding.Ferric Chloride-induced Thrombosis Mouse Model on Carotid Artery and Mesentery Vessel.Peptidase inhibitors in tick physiology.Glandular Matrices and Secretions: Blood-Feeding Arthropods

P2860

Q27680138-A0BDFB92-B75B-48DD-9E80-61457BCA25F2 Q33691654-CBF1FDE9-2999-4132-A001-2966DB143A3C Q33710724-6BACF162-AEF9-4A33-9B9F-92BA9CE71CA9 Q33758079-C68D4C4F-9124-4C9C-B87F-9C565DF5CFE8 Q33758083-657A2446-34C5-4F5D-820D-9FC1A1F0E8CF Q33796652-2D0F6F78-A23E-4E93-AB9E-F031E0DFE715 Q34402606-EE653AE5-E0B0-4C2D-8BC6-035EBAB245E8 Q35575101-3FCE844A-1D85-4084-A1C8-0BAD5C73978E Q35739729-A4355628-B715-4B29-8AB7-83AE58608515 Q36059256-E66F2BA6-701C-451A-AEAB-423D4F3A4524 Q36250499-6E294BEC-A4A8-4A2E-88CA-4365EFE9F555 Q37087491-5B919466-EA1A-4D8E-B39C-C44FE5894AFB Q37105032-4F268EA7-05EB-463B-AF63-8E7CD3025083 Q37390247-2454D066-0B17-4321-AC9C-A7C710F2FF9A Q37412658-2037D5D9-891F-4C4E-BC0B-4B2846135556 Q37897854-2AE00D4A-C94C-441B-A36B-FCB68CF700EF Q38123237-2041532E-F154-457A-8FAF-EC303E53D25E Q38587540-D06A713B-F8E3-4B37-A3A8-64D630B46131 Q38860396-6F3023F6-2E2B-4B0A-8F84-DECCDE89A8EE Q39392693-89FD657D-7495-4F15-A920-3185E65BB419 Q39424930-190B4114-9912-4DC0-BCEE-DD0ABE6FE299 Q40470385-26676FA9-6C12-4C0E-A609-4C4D10247445 Q41769283-30BE1211-81EE-44AA-96F5-F1263EE9ADFA Q50125147-13017905-49E6-4E31-A151-7B8416A7DF9D Q58192117-4A0CDA8D-5ED9-4CDB-9F98-F21428A92566

P2860

Ir-CPI, a coagulation contact phase inhibitor from the tick Ixodes ricinus, inhibits thrombus formation without impairing hemostasis.

http://www.wikidata.org/entity/Q37402410

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 05 October 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Ir-CPI, a coagulation contact ...... without impairing hemostasis.

@en

Ir-CPI, a coagulation contact ...... without impairing hemostasis.

@nl

type

label

Ir-CPI, a coagulation contact ...... without impairing hemostasis.

@en

Ir-CPI, a coagulation contact ...... without impairing hemostasis.

@nl

prefLabel

Ir-CPI, a coagulation contact ...... without impairing hemostasis.

@en

Ir-CPI, a coagulation contact ...... without impairing hemostasis.

@nl

P1433

Q37402410-70BFFF08-34E1-4CEF-94DB-2E71DC6B9908

P1476

Q37402410-B37BEDED-F086-4E32-A7DF-085DC16E0290

P2093

Q37402410-07FDB709-746F-4F4A-A68C-E7DCF0CBC980

Q37402410-33B41C7C-9994-4175-B224-943F52287F7F

Q37402410-555D613F-DC59-4A24-9C4F-9F73BEAD88EF

Q37402410-5AA1A798-4FE4-4096-B106-2B581723D4C3

Q37402410-5C2E2B5F-DBAB-4820-997A-77896752C9EA

Q37402410-753DD43F-A8B8-48E7-BA6B-23B9DB82DE97

Q37402410-8DB67663-F0EE-461E-A404-CF2FC6B8A584

Q37402410-9E61D589-411F-493D-B1EE-0653444263B9

Q37402410-ABCC8CA1-4307-455C-9393-DF25FDB4B020

Q37402410-B1D14C7F-0DC3-4552-8173-62B8667B03BE

P2860

Q37402410-036CD582-6C92-4D6A-95AC-69B0D4B85326

Q37402410-05AFEDB9-7927-4387-B469-5E36BAAB7A4B

Q37402410-084572A1-3B41-4201-B6E7-634BE4FD5B32

Q37402410-08BD99CC-5740-495B-8C23-E2F3AA63E5E4

Q37402410-0FA26952-DFCB-4FA6-9327-15B66F7535B0

Q37402410-12A5C937-B35D-4393-8A38-70A502BBB63A

Q37402410-1DEFF8F2-5339-4080-A419-3551C9EC5095

Q37402410-31BDDD24-7E67-4F7E-969E-07E34DB90E80

Q37402410-3330E288-0D3E-43B8-83D0-7D7652114E6F

Q37402410-3FBCEE8C-A6FC-45C2-84AF-6D3463599AA9

P304

Q37402410-AF9885C2-5E00-45A1-831D-1A54D21AB93D

P31

Q37402410-01722BEB-5041-4E11-9993-CA02B10D539F

P356

Q37402410-831D6540-8DED-44F7-95B1-6A1E07B38DCA

P407

Q37402410-93C542D7-0A4C-4FB8-9F9A-64185AA33453

P433

Q37402410-EA7ECD7E-ECEC-4007-AE56-282A28AA48AC

P478

Q37402410-72A7B419-30D6-4B01-A3A5-7DCF76245617

P577

Q37402410-A3F92681-97D5-44BE-B01A-37A5B758CF28

P5875

Q37402410-8AAAA5C1-A63A-4D5C-A171-CAD99A62F3A6

P698

Q37402410-307C2789-4A59-40B8-A44B-34F6963E51C1

P932

Q37402410-C83CE916-C829-4C2B-95C5-1B54FB0148B5

P356

P1433

Journal of Experimental Medicine

P1476

Ir-CPI, a coagulation contact ...... without impairing hemostasis.

@en

P2093

Chantal Dessy

http://www.w3.org/2001/XMLSchema#string

Edmond Godfroid

http://www.w3.org/2001/XMLSchema#string

Géraldine Rath

http://www.w3.org/2001/XMLSchema#string

Jean-Marie Frère

http://www.w3.org/2001/XMLSchema#string

Jean-Michel Dogné

http://www.w3.org/2001/XMLSchema#string

Jérôme Beaufays

http://www.w3.org/2001/XMLSchema#string

Luc Vanhamme

http://www.w3.org/2001/XMLSchema#string

Olivier Feron

http://www.w3.org/2001/XMLSchema#string

Philippe Cauchie

http://www.w3.org/2001/XMLSchema#string

Séverine Robert

http://www.w3.org/2001/XMLSchema#string

P2860

Hageman-factor-dependent fibrinolysis: generation of fibrinolytic activity by the interaction of human activated factor XI and plasminogen

Defective thrombus formation in mice lacking coagulation factor XII

A new device for measurement of fibrin clot lysis: application to the euglobulin clot lysis time

Calibrated automated thrombin generation measurement in clotting plasma

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

Targeted deletion of murine coagulation factor XII gene-a model for contact phase activation in vivo

Activation of human factor XI (plasma thromboplastin antecedent) by factor XIIa (activated Hageman factor)

Autoactivation of human Hageman factor. Demonstration utilizing a synthetic substrate

Human blood coagulation factor XI. Purification, properties, and mechanism of activation by activated factor XII

Role of arthropod saliva in blood feeding: sialome and post-sialome perspectives

P304

2381-2395

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.20091007

http://www.w3.org/2001/XMLSchema#string

P407

P433

11

http://www.w3.org/2001/XMLSchema#string

P478

206

http://www.w3.org/2001/XMLSchema#string

P577

2009-10-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P5875

26875249

http://www.w3.org/2001/XMLSchema#string

P698

19808248

http://www.w3.org/2001/XMLSchema#string

P932

2768864

http://www.w3.org/2001/XMLSchema#string