Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene.
about
Functional analysis of basic transcription element (BTE)-binding protein (BTEB) 3 and BTEB4, a novel Sp1-like protein, reveals a subfamily of transcriptional repressors for the BTE site of the cytochrome P4501A1 gene promoterRegulation of mouse glutathione S-transferases by chemoprotectors. Molecular evidence for the existence of three distinct alpha-class glutathione S-transferase subunits, Ya1, Ya2, and Ya3, in mouse liverMultiple DNA-binding factors interact with overlapping specificities at the aryl hydrocarbon response element of the cytochrome P450IA1 geneDietary flavonols quercetin and kaempferol are ligands of the aryl hydrocarbon receptor that affect CYP1A1 transcription differentiallyInducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancerMolecular mechanism of inhibition of estrogen-induced cathepsin D gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in MCF-7 cellsThe flavonoid galangin is an inhibitor of CYP1A1 activity and an agonist/antagonist of the aryl hydrocarbon receptorMathematical model developed for environmental samples: prediction of GC/MS dioxin TEQ from XDS-CALUX bioassay dataGlutathione S-transferase Ya subunit gene: identification of regulatory elements required for basal level and inducible expression.A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleusSpecific protein-DNA interactions at a xenobiotic-responsive element: copurification of dioxin receptor and DNA-binding activity.Ah receptor: relevance of mechanistic studies to human risk assessmentDevelopment of bioassays and approaches for the risk assessment of 2,3,7,8-tetrachlorodibenzo-p-dioxin and related compoundsAldehyde dehydrogenases and their role in carcinogenesis.The human hepatic cytochromes P450 involved in drug metabolism.The Ah receptor and the mechanism of dioxin toxicityAnalysis of the upstream elements of the xenobiotic compound-inducible and positionally regulated glutathione S-transferase Ya gene.Liver cells contain constitutive DNase I-hypersensitive sites at the xenobiotic response elements 1 and 2 (XRE1 and -2) of the rat cytochrome P-450IA1 gene and a constitutive, nuclear XRE-binding factor that is distinct from the dioxin receptor.Upstream regulatory region for inducible expression of the chicken skeletal myosin alkali light-chain gene.Duplicated CArG box domains have positive and mutually dependent regulatory roles in expression of the human alpha-cardiac actin gene.In situ protein-DNA interactions at a dioxin-responsive enhancer associated with the cytochrome P1-450 gene.Roles of UDP-glucuronosyltransferases in chemical carcinogenesis.Comparative analysis of dioxin response elements in human, mouse and rat genomic sequences.Substrate-, hormone-, and cAMP-regulated cytochrome P450 degradation.Polychlorinated biphenyls (PCBs), dibenzo-p-dioxins (PCDDs), dibenzofurans (PCDFs), and related compounds: environmental and mechanistic considerations which support the development of toxic equivalency factors (TEFs).Induction of drug-metabolizing enzymes by xenobiotics.Dioxin receptor and C/EBP regulate the function of the glutathione S-transferase Ya gene xenobiotic response element.A novel cis-acting DNA element required for a high level of inducible expression of the rat P-450c gene.Genome-wide screening of dioxin-responsive genes in fetal brain: bioinformatic and experimental approaches.Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements.Structural and mechanistic aspects of transcriptional induction of cytochrome P450 1A1 by benzimidazole derivatives in rat hepatoma H4IIE cells.Signal transduction-mediated activation of the aryl hydrocarbon receptor in rat hepatoma H4IIE cells.Cooperative interaction between AhR.Arnt and Sp1 for the drug-inducible expression of CYP1A1 gene.Aryl hydrocarbon receptor-mediated signal transduction.A bipartite suppressor: conjunction of two distinct factor-binding sites is essential for down-regulation in rat epoxide hydrolase gene expression.Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses.Identification of a novel cis-acting negative regulatory element affecting expression of the CYP1A1 gene in rat epidermal cells.Oltipraz inhibits 3-methylcholanthrene induction of CYP1A1 by CCAAT/enhancer-binding protein activation.Analysis of the promoter of the cytochrome P-450 2B2 gene in the rat.
P2860
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P2860
Location of regulatory elements responsible for drug induction in the rat cytochrome P-450c gene.
description
1986 nî lūn-bûn
@nan
1986年の論文
@ja
1986年学术文章
@wuu
1986年学术文章
@zh-cn
1986年学术文章
@zh-hans
1986年学术文章
@zh-my
1986年学术文章
@zh-sg
1986年學術文章
@yue
1986年學術文章
@zh
1986年學術文章
@zh-hant
name
Location of regulatory element ...... he rat cytochrome P-450c gene.
@en
Location of regulatory element ...... he rat cytochrome P-450c gene.
@nl
type
label
Location of regulatory element ...... he rat cytochrome P-450c gene.
@en
Location of regulatory element ...... he rat cytochrome P-450c gene.
@nl
prefLabel
Location of regulatory element ...... he rat cytochrome P-450c gene.
@en
Location of regulatory element ...... he rat cytochrome P-450c gene.
@nl
P2093
P2860
P356
P1476
Location of regulatory element ...... he rat cytochrome P-450c gene.
@en
P2093
Fujii-Kuriyama Y
Fujisawa-Sehara A
P2860
P304
P356
10.1073/PNAS.83.21.8044
P407
P577
1986-11-01T00:00:00Z