Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degeneration.
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Dysfunction of NMDA receptors in Alzheimer's diseaseMitochondrial permeability transition pore is a potential drug target for neurodegenerationHigh-resolution crystal structures of two crystal forms of human cyclophilin D in complex with PEG 400 moleculesThe emerging role of peptidyl-prolyl isomerase chaperones in tau oligomerization, amyloid processing, and Alzheimer's diseaseIdentification of human ABAD inhibitors for rescuing Aβ-mediated mitochondrial dysfunction.Deregulation of mitochondrial F1FO-ATP synthase via OSCP in Alzheimer's disease.From a Cell's Viewpoint: Targeting Mitochondria in Alzheimer's diseaseSynaptic therapy in Alzheimer's disease: a CREB-centric approach.Oxidative stress-mediated activation of extracellular signal-regulated kinase contributes to mild cognitive impairment-related mitochondrial dysfunctionPhloroglucinol Attenuates the Cognitive Deficits of the 5XFAD Mouse Model of Alzheimer's Disease.Transient Cerebral Ischemia Promotes Brain Mitochondrial Dysfunction and Exacerbates Cognitive Impairments in Young 5xFAD Mice.Synaptosomal Mitochondrial Dysfunction in 5xFAD Mouse Model of Alzheimer's Disease.Increased neuronal PreP activity reduces Aβ accumulation, attenuates neuroinflammation and improves mitochondrial and synaptic function in Alzheimer disease's mouse modelBlockade of cyclophilin D rescues dexamethasone-induced oxidative stress in gingival tissueIdentification of a Small Molecule Cyclophilin D Inhibitor for Rescuing Aβ-Mediated Mitochondrial DysfunctionReduced VDAC1 protects against Alzheimer's disease, mitochondria, and synaptic deficiencies.Geniposide Alleviates Amyloid-Induced Synaptic Injury by Protecting Axonal Mitochondrial Trafficking.SIRT3 in Neural Stem Cells Attenuates Microglia Activation-Induced Oxidative Stress Injury Through Mitochondrial Pathway.Entorhinal Cortex dysfunction can be rescued by inhibition of microglial RAGE in an Alzheimer's disease mouse model.Inhibition of ERK-DLP1 signaling and mitochondrial division alleviates mitochondrial dysfunction in Alzheimer's disease cybrid cellMitochondrial Dysfunction and Synaptic Transmission Failure in Alzheimer's Disease.A Mitocentric View of Alzheimer's Disease.Antioxidants Rescue Mitochondrial Transport in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells.Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice.How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis.The Role of Phosphodiesterase-2 in Psychiatric and Neurodegenerative Disorders.Cyclic nucleotide signaling changes associated with normal aging and age-related diseases of the brain.PINK1 signalling rescues amyloid pathology and mitochondrial dysfunction in Alzheimer's disease.Mitochondrial Perturbation in Alzheimer's Disease and Diabetes.Mitochondrial Dysfunction Triggers Synaptic Deficits via Activation of p38 MAP Kinase Signaling in Differentiated Alzheimer's Disease Trans-Mitochondrial Cybrid Cells.Ginseng Protein Reverses Amyloid Beta Peptide and H2 O2 Cytotoxicity in Neurons, and Ameliorates Cognitive Impairment in AD Rats Induced by a Combination of D-Galactose and AlCl3.Effects of CREB1 gene silencing on cognitive dysfunction by mediating PKA-CREB signaling pathway in mice with vascular dementia.
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Cyclophilin D deficiency rescues Aβ-impaired PKA/CREB signaling and alleviates synaptic degeneration.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 March 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Cyclophilin D deficiency rescu ...... eviates synaptic degeneration.
@en
Cyclophilin D deficiency rescu ...... eviates synaptic degeneration.
@nl
type
label
Cyclophilin D deficiency rescu ...... eviates synaptic degeneration.
@en
Cyclophilin D deficiency rescu ...... eviates synaptic degeneration.
@nl
prefLabel
Cyclophilin D deficiency rescu ...... eviates synaptic degeneration.
@en
Cyclophilin D deficiency rescu ...... eviates synaptic degeneration.
@nl
P2093
P2860
P1476
Cyclophilin D deficiency rescu ...... eviates synaptic degeneration.
@en
P2093
Alexander A Sosunov
Guy M McKhann
John Xi Chen
Shirley ShiDu Yan
Xiaoping Wu
P2860
P304
P356
10.1016/J.BBADIS.2013.03.004
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P433
P577
2013-03-16T00:00:00Z