Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
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Design, function and structure of a monomeric ClC transporterAllostery and Substrate Channeling in the Tryptophan Synthase Bienzyme Complex: Evidence for Two Subunit Conformations and Four Quaternary StatesConformational changes required for H+/Cl− exchange mediated by a CLC transporterA genetically encoded 19F NMR probe for tyrosine phosphorylationThe Origin of Coupled Chloride and Proton Transport in a Cl(-)/H(+) Antiporter13C NMR detects conformational change in the 100-kD membrane transporter ClC-ec1.Antiport mechanism for Cl(-)/H(+) in ClC-ec1 from normal-mode analysis.CLC channels and transporters: proteins with borderline personalities.ATP induces conformational changes in the carboxyl-terminal region of ClC-5On the mechanism of gating charge movement of ClC-5, a human Cl(-)/H(+) antiporterA designed inhibitor of a CLC antiporter blocks function through a unique binding mode.Revealing an outward-facing open conformational state in a CLC Cl(-)/H(+) exchange transporterMultiscale Simulations Reveal Key Aspects of the Proton Transport Mechanism in the ClC-ec1 Antiporter.Water access points and hydration pathways in CLC H+/Cl- transporters.Fluorine-19 NMR of integral membrane proteins illustrated with studies of GPCRs.A tale of two CLCs: biophysical insights toward understanding ClC-5 and ClC-7 function in endosomes and lysosomes.Structure and gating of CLC channels and exchangers.Common gating of both CLC transporter subunits underlies voltage-dependent activation of the 2Cl-/1H+ exchanger ClC-7/Ostm1.Regulatory Conformational Coupling between CLC Anion Channel Membrane and Cytoplasmic Domains.Structural biology. The Tao of chloride transporter structure.Two Cl Ions and a Glu Compete for a Helix Cage in the CLC Proton/Cl- Antiporter.Multiscale Kinetic Modeling Reveals an Ensemble of Cl-/H+ Exchange Pathways in ClC-ec1 Antiporter.Chloride Ion Transport by the E. coli CLC Cl-/H+ Antiporter: A Combined Quantum-Mechanical and Molecular-Mechanical Study.
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Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
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article científic
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artigo científico
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bilimsel makale
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scientific article published on 10 September 2009
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vedecký článok
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vetenskaplig artikel
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Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
@en
Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
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type
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Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
@en
Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
@nl
prefLabel
Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
@en
Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
@nl
P2093
P2860
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P1433
P1476
Substrate-driven conformational changes in ClC-ec1 observed by fluorine NMR.
@en
P2093
Corey W Liu
Merritt C Maduke
Shelley M Elvington
P2860
P304
P356
10.1038/EMBOJ.2009.259
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P577
2009-09-10T00:00:00Z