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Targeting SOD1 reduces experimental non–small-cell lung cancer

Targeting SOD1 reduces experimental non–small-cell lung cancer

http://www.wikidata.org/entity/Q37410635

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Fundamentals of cancer metabolism Oxidative stress and the unfulfilled promises of antioxidant agents Oxygen in human health from life to death--An approach to teaching redox biology and signaling to graduate and medical students Targeting mitochondria metabolism for cancer therapy Relationships between chronic obstructive pulmonary disease and lung cancer: biological insights A Central Role for JNK/AP-1 Pathway in the Pro-Oxidant Effect of Pyrrolidine Dithiocarbamate through Superoxide Dismutase 1 Gene Repression and Reactive Oxygen Species Generation in Hematopoietic Human Cancer Cell Line U937 ROS function in redox signaling and oxidative stress Molecular pathways and therapeutic targets in lung cancer Sclareol inhibits cell proliferation and sensitizes cells to the antiproliferative effect of bortezomib via upregulating the tumor suppressor caveolin-1 in cervical cancer cells.SOD1, an unexpected novel target for cancer therapy Copper-zinc superoxide dismutase-mediated redox regulation of bortezomib resistance in multiple myeloma.Mitochondrial sirtuins and their relationships with metabolic disease and cancer.A Synthetic Lethal Interaction between Glutathione Synthesis and Mitochondrial Reactive Oxygen Species Provides a Tumor-Specific Vulnerability Dependent on STAT3.Inhibition of Prostaglandin Reductase 2, a Putative Oncogene Overexpressed in Human Pancreatic Adenocarcinoma, Induces Oxidative Stress-Mediated Cell Death Involving xCT and CTH Gene Expressions through 15-Keto-PGE2 Nitric oxide is a positive regulator of the Warburg effect in ovarian cancer cells Oxidative stress inhibits distant metastasis by human melanoma cells.Targeting Tyrosine Kinase Inhibitor-Resistant Non-Small Cell Lung Cancer by Inducing Epidermal Growth Factor Receptor Degradation via Methionine 790 Oxidation Using Sensors and Generators of H2O2 to Elucidate the Toxicity Mechanism of Piperlongumine and Phenethyl Isothiocyanate.REDOX IMBALANCE IN LUNG CANCER OF PATIENTS WITH UNDERLYING CHRONIC RESPIRATORY CONDITIONS.Mitochondrial reactive oxygen species and cancer.Sirtuins and the Metabolic Hurdles in Cancer.Expanding roles of superoxide dismutases in cell regulation and cancer Agents in the preclinical development stage for non-small cell lung cancer.Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-mediated Inhibition of Mitochondrial Respiration.Depletion of the Human Ion Channel TRPM2 in Neuroblastoma Demonstrates Its Key Role in Cell Survival through Modulation of Mitochondrial Reactive Oxygen Species and Bioenergetics.ROS in Cancer: The Burning Question.Paradoxical roles of dual oxidases in cancer biology.Human Metapneumovirus Infection in Chronic Obstructive Pulmonary Disease: Impact of Glucocorticosteroids and Interferon.Differential proteomic analysis reveals that EGCG inhibits HDGF and activates apoptosis to increase the sensitivity of non-small cells lung cancer to chemotherapy.Terpinen-4-ol inhibits colorectal cancer growth via reactive oxygen species.Epigenetics and Oxidative Stress in Aging.Absence of manganese superoxide dismutase delays p53-induced tumor formation The orally active pterocarpanquinone LQB-118 exhibits cytotoxicity in prostate cancer cell and tumor models through cellular redox stress.Actein alleviates 2,3,7,8-tetrachlorodibenzo-p-dioxin-mediated cellular dysfunction in osteoblastic MC3T3-E1 cells.Cancer, Oxidative Stress, and Metastasis.Mitochondrial Changes in Cancer.Novel targets for sensitizing breast cancer cells to TRAIL-induced apoptosis with siRNA delivery.Convergence of miR-143 overexpression, oxidative stress and cell death in HCT116 human colon cancer cells.CANCER. Revisiting vitamin C and cancer.Therapeutic potentials of superoxide dismutase.

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Targeting SOD1 reduces experimental non–small-cell lung cancer

http://www.wikidata.org/entity/Q37410635

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on January 2014

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Targeting SOD1 reduces experimental non–small-cell lung cancer

@en

Targeting SOD1 reduces experimental non–small-cell lung cancer.

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type

label

Targeting SOD1 reduces experimental non–small-cell lung cancer

@en

Targeting SOD1 reduces experimental non–small-cell lung cancer.

@nl

prefLabel

Targeting SOD1 reduces experimental non–small-cell lung cancer

@en

Targeting SOD1 reduces experimental non–small-cell lung cancer.

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Journal of Clinical Investigation

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Targeting SOD1 reduces experimental non–small-cell lung cancer

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Andrea Glasauer

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Andrew P Mazar

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Laura A Sena

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Lauren P Diebold

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Navdeep S Chandel

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P2860

Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways

Chemical genomics identifies small-molecule MCL1 repressors and BCL-xL as a predictor of MCL1 dependency

RETRACTED: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

Characterizing the cancer genome in lung adenocarcinoma.

Oncogene-induced Nrf2 transcription promotes ROS detoxification and tumorigenesis

Gefitinib-sensitizing EGFR mutations in lung cancer activate anti-apoptotic pathways

Regulation of cancer cell metabolism

Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoximine)

The copper chelator ATN-224 induces peroxynitrite-dependent cell death in hematological malignancies

The landscape of somatic copy-number alteration across human cancers.

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117-128

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scholarly article

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10.1172/JCI71714

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1

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124

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2014-01-01T00:00:00Z

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24292713

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3871252

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