Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model.
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Notch1-induced T cell leukemia can be potentiated by microenvironmental cues in the spleen.Treatment of chronic myelogenous leukemia by blocking cytokine alterations found in normal stem and progenitor cellsExcessive proliferation and impaired function of primitive hematopoietic cells in bone marrow due to senescence post chemotherapy in a T cell acute lymphoblastic leukemia model.Leukemic marrow infiltration reveals a novel role for Egr3 as a potent inhibitor of normal hematopoietic stem cell proliferation.Digitalization of a non-irradiated acute myeloid leukemia model.The regulation of normal and leukemic hematopoietic stem cells by niches.Functional Niche Competition Between Normal Hematopoietic Stem and Progenitor Cells and Myeloid Leukemia CellsHes1 mediates the different responses of hematopoietic stem and progenitor cells to T cell leukemic environmentThe ecology in the hematopoietic stem cell niche determines the clinical outcome in chronic myeloid leukemia.The bone marrow microenvironment and leukemia: biology and therapeutic targeting.Mechanisms of defective erythropoiesis and anemia in pediatric acute lymphoblastic leukemia (ALL).Microenvironmental cues for T-cell acute lymphoblastic leukemia development.Concise Review: Stem Cell Population Biology: Insights from Hematopoiesis.Neoplasms in the bone marrow niches: disturbance of the microecosystem.Bortezomib suppresses the growth of leukemia cells with Notch1 overexpression in vivo and in vitro.MLL-ENL leukemia burden initiated in femoral diaphysis and preceded by mature B-cell depletion.Feedback mechanisms control coexistence in a stem cell model of acute myeloid leukaemia.Hematopoiesis in patients with mature B-cell malignancies is deregulated even in patients with undetectable bone marrow involvement.Altered mesenchymal niche cells impede generation of normal hematopoietic progenitor cells in leukemic bone marrow.Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-κB and β-catenin/TCF signaling pathways.
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P2860
Kinetics of normal hematopoietic stem and progenitor cells in a Notch1-induced leukemia model.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 August 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Kinetics of normal hematopoiet ...... Notch1-induced leukemia model.
@en
Kinetics of normal hematopoiet ...... Notch1-induced leukemia model.
@nl
type
label
Kinetics of normal hematopoiet ...... Notch1-induced leukemia model.
@en
Kinetics of normal hematopoiet ...... Notch1-induced leukemia model.
@nl
prefLabel
Kinetics of normal hematopoiet ...... Notch1-induced leukemia model.
@en
Kinetics of normal hematopoiet ...... Notch1-induced leukemia model.
@nl
P2093
P2860
P1433
P1476
Kinetics of normal hematopoiet ...... Notch1-induced leukemia model
@en
P2093
Hongmei Shen
Jianmin Wang
Richard XuFeng
Xiaoxia Hu
P2860
P304
P356
10.1182/BLOOD-2009-06-227843
P407
P577
2009-08-03T00:00:00Z