Conditional stabilization of beta-catenin expands the pool of lung stem cells.
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Adult lung stem cells and their contribution to lung tumourigenesisThe research progress about Wnt pathway of lung cancer stem cellsAltered lung morphogenesis, epithelial cell differentiation and mechanics in mice deficient in the Wnt/β-catenin antagonist ChibbyRepair of tracheal epithelium by basal cells after chlorine-induced injuryRoles for β-catenin and doxycycline in the regulation of respiratory epithelial cell frequency and functionWnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregutbeta-Catenin promotes respiratory progenitor identity in mouse foregutCommentary: Sca-1 and Cells of the Lung: A matter of Different SortsSox2 is required for maintenance and differentiation of bronchiolar Clara, ciliated, and goblet cells.Beta-catenin/T-cell factor signaling is activated during lung injury and promotes the survival and migration of alveolar epithelial cellsEvidence for self-renewing lung cancer stem cells and their implications in tumor initiation, progression, and targeted therapy.Down-regulation of the canonical Wnt β-catenin pathway in the airway epithelium of healthy smokers and smokers with COPD.The human airway epithelial basal cell transcriptome.Epithelial repair mechanisms in the lungTracheal Basal cells: a facultative progenitor cell pool.Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate.National Heart, Lung, and Blood Institute perspective: lung progenitor and stem cells--gaps in knowledge and future opportunities.Expression of canonical WNT/β-CATENIN signaling components in the developing human lung.Maintenance of the bronchial alveolar stem cells in an undifferentiated state by secreted frizzled-related protein 1.Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signalingWnt/β-catenin signaling accelerates mouse lung tumorigenesis by imposing an embryonic distal progenitor phenotype on lung epithelium.Wnt pathway aberrations including autocrine Wnt activation occur at high frequency in human non-small-cell lung carcinoma.Cancer stem cell radioresistance and enrichment: where frontline radiation therapy may fail in lung and esophageal cancersThe three R's of lung health and disease: repair, remodeling, and regeneration.β-catenin dosage is a critical determinant of tracheal basal cell fate determination.Functional analysis of two distinct bronchiolar progenitors during lung injury and repair.Wnt and FGF mediated epithelial-mesenchymal crosstalk during lung development.Context-dependent differentiation of multipotential keratin 14-expressing tracheal basal cells.A single cell functions as a tissue-specific stem cell and the in vitro niche-forming cell.Parabronchial smooth muscle constitutes an airway epithelial stem cell niche in the mouse lung after injury.Characterization of the cell of origin for small cell lung cancerDirect and indirect roles for β-catenin in facultative basal progenitor cell differentiationβ-Catenin-SOX2 signaling regulates the fate of developing airway epithelium.WNT signaling increases proliferation and impairs differentiation of stem cells in the developing cerebellum.β-Catenin determines upper airway progenitor cell fate and preinvasive squamous lung cancer progression by modulating epithelial-mesenchymal transition.XB130 promotes bronchioalveolar stem cell and Club cell proliferation in airway epithelial repair and regeneration.Genetic Variants in MMP9 and TCF2 Contribute to Susceptibility to Lung CancerWnt and Frizzled RNA expression in human mesenchymal and embryonic (H7) stem cells.Bmi1 is critical for lung tumorigenesis and bronchioalveolar stem cell expansion.β-catenin in the alveolar epithelium protects from lung fibrosis after intratracheal bleomycin.
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P2860
Conditional stabilization of beta-catenin expands the pool of lung stem cells.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 20 March 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Conditional stabilization of beta-catenin expands the pool of lung stem cells.
@en
Conditional stabilization of beta-catenin expands the pool of lung stem cells.
@nl
type
label
Conditional stabilization of beta-catenin expands the pool of lung stem cells.
@en
Conditional stabilization of beta-catenin expands the pool of lung stem cells.
@nl
prefLabel
Conditional stabilization of beta-catenin expands the pool of lung stem cells.
@en
Conditional stabilization of beta-catenin expands the pool of lung stem cells.
@nl
P2093
P2860
P1433
P1476
Conditional stabilization of beta-catenin expands the pool of lung stem cells.
@en
P2093
Adam Giangreco
Anna C Zemke
Barry R Stripp
Brian L Brockway
Jeffrey A Drake
Mark M Taketo
Peter Y P Di
Roxana M Teisanu
Susan D Reynolds
Thomas Mariani
P2860
P304
P356
10.1634/STEMCELLS.2008-0053
P577
2008-03-20T00:00:00Z