HPV E6 protein interacts physically and functionally with the cellular telomerase complex.
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The E3 ubiquitin ligase UBE3A is an integral component of the molecular circadian clock through regulating the BMAL1 transcription factorTranscription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) GeneRegulation of the Wnt/β-Catenin Signaling Pathway by Human Papillomavirus E6 and E7 OncoproteinsHuman Papillomavirus (HPV)-associated Oral Cancers and Treatment StrategiesStructural Insights into a Wildtype Domain of the Oncoprotein E6 and Its Interaction with a PDZ DomainTelomeres and telomerase in head and neck squamous cell carcinoma: from pathogenesis to clinical implications.Papillomavirus E6 oncoproteins.HPV16 E7 protein and hTERT proteins defective for telomere maintenance cooperate to immortalize human keratinocytesThe HPV-16 E5 protein represses expression of stress pathway genes XBP-1 and COX-2 in genital keratinocytes.ROCK inhibitor and feeder cells induce the conditional reprogramming of epithelial cellsHigh-risk human papillomavirus E6 protein promotes reprogramming of Fanconi anemia patient cells through repression of p53 but does not allow for sustained growth of induced pluripotent stem cells.The ING4 Binding with p53 and Induced p53 Acetylation were Attenuated by Human Papillomavirus 16 E6.Suppression of STAT-1 expression by human papillomaviruses is necessary for differentiation-dependent genome amplification and plasmid maintenance.Targeting the human papillomavirus E6 and E7 oncogenes through expression of the bovine papillomavirus type 1 E2 protein stimulates cellular motility.RECQ1 interacts with FEN-1 and promotes binding of FEN-1 to telomeric chromatin.Association between hTERT activation by HPV E6 proteins and oncogenic risk.The Asian-American E6 variant protein of human papillomavirus 16 alone is sufficient to promote immortalization, transformation, and migration of primary human foreskin keratinocytes.Zinc finger arrays binding human papillomavirus types 16 and 18 genomic DNA: precursors of gene-therapeutics for in-situ reversal of associated cervical neoplasiaTelomeres and viruses: common themes of genome maintenance.TERT promoter mutations occur frequently in gliomas and a subset of tumors derived from cells with low rates of self-renewalCellular transformation by human papillomaviruses: lessons learned by comparing high- and low-risk virusesHPV16 E6 upregulates Aurora A expression.Risk of progression of early cervical lesions is associated with integration and persistence of HPV-16 and expression of E6, Ki-67, and telomerase.Regulation of the life cycle of HPVs by differentiation and the DNA damage responseNext-generation treatment strategies for human papillomavirus-related head and neck squamous cell carcinoma: where do we go?The HPV16 oncogenes cause aberrant stem cell mobilization.Signaling pathways in HPV-associated cancers and therapeutic implications.The Molecular Landscape of Recurrent and Metastatic Head and Neck Cancers: Insights From a Precision Oncology Sequencing Platform.Telomerase Induction in HPV Infection and Oncogenesis.High-risk human papillomavirus infection associated with telomere elongation in patients with esophageal squamous cell carcinoma with poor prognosis.Revealing highly conserved regions in the E6 protein among distinct human papillomavirus types using comparative analysis of multiple sequence alignments.ROCK inhibitor reduces Myc-induced apoptosis and mediates immortalization of human keratinocytes.TIP60 represses telomerase expression by inhibiting Sp1 binding to the TERT promoter.Novel insights into epigenetic drivers of oropharyngeal squamous cell carcinoma: role of HPV and lifestyle factors.Terc is dispensable for most of the short-term HPV16 oncogene-mediated phenotypes in mice.
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P2860
HPV E6 protein interacts physically and functionally with the cellular telomerase complex.
description
article científic
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article scientifique
@fr
articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 20 October 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
HPV E6 protein interacts physi ...... e cellular telomerase complex.
@en
HPV E6 protein interacts physi ...... e cellular telomerase complex.
@nl
type
label
HPV E6 protein interacts physi ...... e cellular telomerase complex.
@en
HPV E6 protein interacts physi ...... e cellular telomerase complex.
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prefLabel
HPV E6 protein interacts physi ...... e cellular telomerase complex.
@en
HPV E6 protein interacts physi ...... e cellular telomerase complex.
@nl
P2093
P2860
P356
P1476
HPV E6 protein interacts physi ...... e cellular telomerase complex.
@en
P2093
Aleksandra Dakic
Renxiang Chen
Richard Schlegel
Xuefeng Liu
Yiyu Zhang
P2860
P304
18780-18785
P356
10.1073/PNAS.0906357106
P407
P577
2009-10-20T00:00:00Z