Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin.
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Structural characteristics of the hydrophobic patch of azurin and its interaction with p53: a site-directed spin labeling study.Bacterial proteins and peptides in cancer therapy: today and tomorrowThe bacterial protein azurin impairs invasion and FAK/Src signaling in P-cadherin-overexpressing breast cancer cell models.Re-engineered p53 activates apoptosis in vivo and causes primary tumor regression in a dominant negative breast cancer xenograft model.Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis.Potent and tumor specific: arming bacteria with therapeutic proteins.Molecular dynamic simulation insights into the normal state and restoration of p53 function.Escherichia coli Nissle 1917 targets and restrains mouse B16 melanoma and 4T1 breast tumors through expression of azurin protein.ROS and p53: a versatile partnershipMicrobial-based therapy of cancer: current progress and future prospects.Engineering of bacterial strains and their products for cancer therapy.SERS-based nanobiosensing for ultrasensitive detection of the p53 tumor suppressor.Structural studies on Laz, a promiscuous anticancer Neisserial protein.Peptides and peptidomimetics in the p53/MDM2/MDM4 circuitry - a patent review.Building Cell Selectivity into CPP-Mediated Strategies.A cell penetrating peptide derived from azurin inhibits angiogenesis and tumor growth by inhibiting phosphorylation of VEGFR-2, FAK and Akt.Interaction of an anticancer peptide fragment of azurin with p53 and its isolated domains studied by atomic force spectroscopy.Preclinical pharmacokinetics, metabolism, and toxicity of azurin-p28 (NSC745104) a peptide inhibitor of p53 ubiquitination.The construction of the eukaryotic expression plasmid pcDNA3.1/azurin and the increased apoptosis of U2OS cells transfected with it.Discovery of Azurin-Like Anticancer Bacteriocins from Human Gut Microbiome through Homology Modeling and Molecular Docking against the Tumor Suppressor p53Modulation of membrane properties of lung cancer cells by azurin enhances the sensitivity to EGFR-targeted therapy and decreased β1 integrin-mediated adhesion.Bacterial azurin in potential cancer therapyBacterial cupredoxin azurin hijacks cellular signaling networks: Protein-protein interactions and cancer therapy.Identification of Staphylococcus aureus α-hemolysin as a protein drug that is secreted by anticancer bacteria and rapidly kills cancer cells.
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P2860
Apoptosis or growth arrest: Modulation of tumor suppressor p53's specificity by bacterial redox protein azurin.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 24 March 2004
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Apoptosis or growth arrest: Mo ...... acterial redox protein azurin.
@en
Apoptosis or growth arrest: Mo ...... acterial redox protein azurin.
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type
label
Apoptosis or growth arrest: Mo ...... acterial redox protein azurin.
@en
Apoptosis or growth arrest: Mo ...... acterial redox protein azurin.
@nl
prefLabel
Apoptosis or growth arrest: Mo ...... acterial redox protein azurin.
@en
Apoptosis or growth arrest: Mo ...... acterial redox protein azurin.
@nl
P2093
P2860
P356
P1476
Apoptosis or growth arrest: Mo ...... acterial redox protein azurin.
@en
P2093
Ananda M Chakrabarty
Benjamin S Avner
Kazuhide Kimbara
Masateru Ikehata
Tapas K Das Gupta
Tohru Yamada
Yoshinori Hiraoka
P2860
P304
P356
10.1073/PNAS.0400899101
P407
P577
2004-03-24T00:00:00Z