Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma
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OSU-A9 inhibits pancreatic cancer cell lines by modulating p38-JAK-STAT3 signalingSmac mimetic SM-164 potentiates APO2L/TRAIL- and doxorubicin-mediated anticancer activity in human hepatocellular carcinoma cellsIndole-3-carbinol inhibits tumorigenicity of hepatocellular carcinoma cells via suppression of microRNA-21 and upregulation of phosphatase and tensin homolog.Antitumor effects of OSU-2S, a nonimmunosuppressive analogue of FTY720, in hepatocellular carcinoma.Tangeretin Alleviates Cisplatin-Induced Acute Hepatic Injury in Rats: Targeting MAPKs and Apoptosis.Creation of a murine orthotopic hepatoma model with intra-abdominal metastasis.Co-culture of hepatoma cells with hepatocytic precursor (stem-like) cells inhibits tumor cell growth and invasion by downregulating Akt/NF-κB expression.Targeted regulation of PI3K/Akt/mTOR/NF-κB signaling by indole compounds and their derivatives: mechanistic details and biological implications for cancer therapyModulation of cyclins, p53 and mitogen-activated protein kinases signaling in breast cancer cell lines by 4-(3,4,5-trimethoxyphenoxy)benzoic acidDiosmin attenuates radiation-induced hepatic fibrosis by boosting PPAR-γ expression and hampering miR-17-5p-activated canonical Wnt-β-catenin signaling.Sensitization of hepatocellular carcinoma cells to Apo2L/TRAIL by a novel Akt/NF-κB signalling inhibitor.Wortmannin reduces metastasis and angiogenesis of human breast cancer cells via nuclear factor-κB-dependent matrix metalloproteinase-9 and interleukin-8 pathways.Mild synthetic approach to novel indole-1-carbinols and preliminary evaluation of their cytotoxicity in hepatocarcinoma cells.Ent-11α-hydroxy-15-oxo-kaur-16-en-19-oic-acid inhibits hepatocellular carcinoma in vitro and in vivo via stabilizing IkBα.OSU-2S/Sorafenib Synergistic Antitumor Combination against Hepatocellular Carcinoma: The Role of PKCδ/p53.OSU-CG5, a novel energy restriction mimetic agent, targets human colorectal cancer cells in vitro.The expression of Survivin and NF-κB associated with prognostically worse clinicopathologic variables in hepatocellular carcinoma.Synthesis, anti-breast cancer activity, and molecular modeling of some benzothiazole and benzoxazole derivatives.Antrodia cinnamomea boosts the anti-tumor activity of sorafenib in xenograft models of human hepatocellular carcinoma
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Targeting of the Akt-nuclear factor-kappa B signaling network by [1-(4-chloro-3-nitrobenzenesulfonyl)-1H-indol-3-yl]-methanol (OSU-A9), a novel indole-3-carbinol derivative, in a mouse model of hepatocellular carcinoma
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article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
@tr
scientific article published on 25 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Targeting of the Akt-nuclear f ...... el of hepatocellular carcinoma
@en
Targeting of the Akt-nuclear f ...... l of hepatocellular carcinoma.
@nl
type
label
Targeting of the Akt-nuclear f ...... el of hepatocellular carcinoma
@en
Targeting of the Akt-nuclear f ...... l of hepatocellular carcinoma.
@nl
prefLabel
Targeting of the Akt-nuclear f ...... el of hepatocellular carcinoma
@en
Targeting of the Akt-nuclear f ...... l of hepatocellular carcinoma.
@nl
P2093
P2860
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P1476
Targeting of the Akt-nuclear f ...... el of hepatocellular carcinoma
@en
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Aaron M Sargeant
Ching-Shih Chen
Dasheng Wang
Jing-Ru Weng
Samuel K Kulp
Tushar Patel
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P304
P356
10.1124/MOL.109.058180
P50
P577
2009-08-25T00:00:00Z