Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
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MT1-MMP cleaves Dll1 to negatively regulate Notch signalling to maintain normal B-cell developmentIs lineage decision-making restricted during tumoral reprograming of haematopoietic stem cells?Endothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle developmentTargeting the mechanisms of resistance to chemotherapy and radiotherapy with the cancer stem cell hypothesis.Dose-dependent effects of the Notch ligand Delta1 on ex vivo differentiation and in vivo marrow repopulating ability of cord blood cellsNotch2 governs the rate of generation of mouse long- and short-term repopulating stem cellsGrowth factor independent-1 maintains Notch1-dependent transcriptional programming of lymphoid precursors.T cells develop normally in the absence of both Deltex1 and Deltex2Notch regulates cytolytic effector function in CD8+ T cells.Resuscitating cancer immunosurveillance: selective stimulation of DLL1-Notch signaling in T cells rescues T-cell function and inhibits tumor growth.Regulation of dendritic-cell differentiation by bone marrow stroma via different Notch ligands.A genetic screen for modifiers of the delta1-dependent notch signaling function in the mouse.Propensity of adult lymphoid progenitors to progress to DN2/3 stage thymocytes with Notch receptor ligation.Notch-dependent T-lineage commitment occurs at extrathymic sites following bone marrow transplantation.The RhoA transcriptional program in pre-T cells.Differential synergy of Notch and T cell receptor signaling determines alphabeta versus gammadelta lineage fate.Hierarchy of Notch-Delta interactions promoting T cell lineage commitment and maturationLack of Foxp3 function and expression in the thymic epitheliumEstablishment and functioning of intrathymic microenvironments.Regulation of intrathymic T-cell development by Lunatic Fringe- Notch1 interactions.T-cell development, doing it in a dish.Developmental regulation of Foxp3 expression during ontogeny.Density of the Notch ligand Delta1 determines generation of B and T cell precursors from hematopoietic stem cells.Notch signaling in T-cell acute lymphoblastic leukemia.Notch 1 activation in the molecular pathogenesis of T-cell acute lymphoblastic leukaemia.Notch and Wnt signaling in T-lymphocyte development and acute lymphoblastic leukemia.Itch-/- alphabeta and gammadelta T cells independently contribute to autoimmunity in Itchy miceLunatic fringe enhances competition for delta-like Notch ligands but does not overcome defective pre-TCR signaling during thymocyte beta-selection in vivo.Dendritic cell-mediated NK cell activation is controlled by Jagged2-Notch interaction.Development and maturation of natural killer cellsIntegrated morphogen signal inputs in gammadelta versus alphabeta T-cell differentiation.X-ray irradiation selectively kills thymocytes of different stages and impairs the maturation of donor-derived CD4(+)CD8(+) thymocytes in recipient thymus.MicroRNA function in NK-cell biology.Soluble forms of the Notch ligands Delta1 and Jagged1 promote in vivo tumorigenicity in NIH3T3 fibroblasts with distinct phenotypesJagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions.Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment.Therapeutic implications of leukemic stem cell pathwaysTranscription factors as therapeutic targets in lymphoid malignancies.Competition and collaboration: GATA-3, PU.1, and Notch signaling in early T-cell fate determination.Proteome analysis of Plasmodium falciparum extracellular secretory antigens at asexual blood stages reveals a cohort of proteins with possible roles in immune modulation and signaling.
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P2860
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 14 October 2004
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
@en
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
@nl
type
label
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
@en
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
@nl
prefLabel
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
@en
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
@nl
P2093
P2860
P1433
P1476
Notch ligands Delta 1 and Jagged1 transmit distinct signals to T-cell precursors.
@en
P2093
Andrew G Farr
James Dooley
Michael J Bevan
Sophie M Lehar
P2860
P304
P356
10.1182/BLOOD-2004-08-3257
P407
P577
2004-10-14T00:00:00Z