Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.
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C. elegans aging is modulated by hydrogen sulfide and the sulfhydrylase/cysteine synthase cysl-2Caenorhabditis elegans as a model organism to study APP functionmTORC1 signaling activates NRF1 to increase cellular proteasome levelsGraded Proteasome Dysfunction in Caenorhabditis elegans Activates an Adaptive Response Involving the Conserved SKN-1 and ELT-2 Transcription Factors and the Autophagy-Lysosome PathwayRegulation of synaptic nlg-1/neuroligin abundance by the skn-1/Nrf stress response pathway protects against oxidative stressIntegration of the unfolded protein and oxidative stress responses through SKN-1/NrfThe conserved SKN-1/Nrf2 stress response pathway regulates synaptic function in Caenorhabditis elegansSurveillance-Activated Defenses Block the ROS–Induced Mitochondrial Unfolded Protein ResponseGenetic and cellular characterization of Caenorhabditis elegans mutants abnormal in the regulation of many phase II enzymesInduction of cytoprotective pathways is central to the extension of lifespan conferred by multiple longevity pathwaysExtension of lifespan in C. elegans by naphthoquinones that act through stress hormesis mechanismsSpecific SKN-1/Nrf stress responses to perturbations in translation elongation and proteasome activityETS-4 is a transcriptional regulator of life span in Caenorhabditis elegansGlucose induces sensitivity to oxygen deprivation and modulates insulin/IGF-1 signaling and lipid biosynthesis in Caenorhabditis elegans.The role of insulin/IGF-1 signaling in the longevity of model invertebrates, C. elegans and D. melanogasterTOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxODopamine signaling promotes the xenobiotic stress response and protein homeostasisEnhanced oxidative stress resistance through activation of a zinc deficiency transcription factor in Brachypodium distachyonExtracellular dopamine potentiates mn-induced oxidative stress, lifespan reduction, and dopaminergic neurodegeneration in a BLI-3-dependent manner in Caenorhabditis elegansA role for SKN-1/Nrf in pathogen resistance and immunosenescence in Caenorhabditis elegansAn ultra high-throughput, whole-animal screen for small molecule modulators of a specific genetic pathway in Caenorhabditis elegansGain-of-Function Alleles in Caenorhabditis elegans Nuclear Hormone Receptor nhr-49 Are Functionally DistinctMutations in Nonessential eIF3k and eIF3l Genes Confer Lifespan Extension and Enhanced Resistance to ER Stress in Caenorhabditis elegansFunctional and phylogenetic characterization of proteins detected in various nematode intestinal compartments.Stress and aging induce distinct polyQ protein aggregation statesDauer-independent insulin/IGF-1-signalling implicates collagen remodelling in longevity.Remodeling of Proteostasis Upon Transition to Adulthood is Linked to Reproduction Onset.WDR23 regulates NRF2 independently of KEAP1.SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network.A cytoprotective perspective on longevity regulationTERT promoter mutations lead to high transcriptional activity under hypoxia and temozolomide treatment and predict poor prognosis in gliomas.skn-1-Dependent and -independent regulation of aip-1 expression following metabolic stress in Caenorhabditis elegans.High-throughput screening and biosensing with fluorescent C. elegans strains.A conserved PHD finger protein and endogenous RNAi modulate insulin signaling in Caenorhabditis elegansHIF-1 and SKN-1 coordinate the transcriptional response to hydrogen sulfide in Caenorhabditis elegans.RNAi screening implicates a SKN-1-dependent transcriptional response in stress resistance and longevity deriving from translation inhibition.Direct interaction between the WD40 repeat protein WDR-23 and SKN-1/Nrf inhibits binding to target DNA.Ce-Duox1/BLI-3 generated reactive oxygen species trigger protective SKN-1 activity via p38 MAPK signaling during infection in C. elegans.Genome-wide screening identifies new genes required for stress-induced phase 2 detoxification gene expression in animals.D-beta-hydroxybutyrate extends lifespan in C. elegans.
P2860
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P2860
Condition-adapted stress and longevity gene regulation by Caenorhabditis elegans SKN-1/Nrf.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 03 July 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Condition-adapted stress and l ...... norhabditis elegans SKN-1/Nrf.
@en
Condition-adapted stress and l ...... norhabditis elegans SKN-1/Nrf.
@nl
type
label
Condition-adapted stress and l ...... norhabditis elegans SKN-1/Nrf.
@en
Condition-adapted stress and l ...... norhabditis elegans SKN-1/Nrf.
@nl
prefLabel
Condition-adapted stress and l ...... norhabditis elegans SKN-1/Nrf.
@en
Condition-adapted stress and l ...... norhabditis elegans SKN-1/Nrf.
@nl
P2093
P2860
P1433
P1476
Condition-adapted stress and l ...... enorhabditis elegans SKN-1/Nrf
@en
P2093
Jasmine Ashraf
Jess Porter Abate
Jessica Landis
Kieran Dilks
T Keith Blackwell
P2860
P304
P356
10.1111/J.1474-9726.2009.00501.X
P577
2009-07-03T00:00:00Z