Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.
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Chiral discrimination in platinum anticancer drugs.Conformation, protein recognition and repair of DNA interstrand and intrastrand cross-links of antitumor trans-[PtCl2(NH3)(thiazole)].Crystal structure of a double-stranded DNA containing a cisplatin interstrand cross-link at 1.63 A resolution: hydration at the platinated siteX-ray structure and mechanism of RNA polymerase II stalled at an antineoplastic monofunctional platinum-DNA adductSubstrate specificity and sequence-dependent activity of the Saccharomyces cerevisiae 3-methyladenine DNA glycosylase (Mag)Nucleolar damage correlates with neurotoxicity induced by different platinum drugsPotentiating effect of UVA irradiation on anticancer activity of Carboplatin derivatives involving 7-azaindolesPhotoaffinity labeling reveals nuclear proteins that uniquely recognize cisplatin-DNA interstrand cross-linksC. elegans whole-genome sequencing reveals mutational signatures related to carcinogens and DNA repair deficiencyDetection of platinum-DNA adducts by 32P-postlabelling.Structure-dependent bypass of DNA interstrand crosslinks by translesion synthesis polymerases.Upregulation of TPX2 by STAT3: identification of a novel STAT3 binding site.DNA double helix promotes a linkage isomerization reaction in trans-diamminedichloroplatinum(II)-modified DNA.Tracking the genomic evolution of esophageal adenocarcinoma through neoadjuvant chemotherapy.Repair synthesis by human cell extracts in cisplatin-damaged DNA is preferentially determined by minor adductsDNA interstrand cross-links of trans-diamminedichloroplatinum(II) are preferentially formed between guanine and complementary cytosine residuesA new anticancer platinum compound, (-)-(R)-2-aminomethyl-pyrrolidine(1,1-cyclobutanedicarboxylato) platinum(II): DNA interstrand crosslinking, repair and lethal effects in normal human, Fanconi's anaemia and xeroderma pigmentosum cells.A comprehensive survey of the mutagenic impact of common cancer cytotoxicsEngineering terminal disulfide bonds into DNA.Inhibition of transcription by platinum antitumor compoundsDNA bending and unwinding due to the major 1,2-GG intrastrand cross-link formed by antitumor cis-diamminedichloroplatinum(II) are flanking-base independent.Different recognition of DNA modified by aatitumor cisplatin and its clinically ineffective trans isomer by tumor suppressor protein p53.Sequence specificity, conformation, and recognition by HMG1 protein of major DNA interstrand cross-links of antitumor dinuclear platinum complexes.Diazido mixed-amine platinum(IV) anticancer complexes activatable by visible-light form novel DNA adducts.DNA binding selectivity of oligopyridine-ruthenium(II)-lysine conjugate.DNA-protein cross-linking by trans-[PtCl(2)(E-iminoether)(2)]. A concept for activation of the trans geometry in platinum antitumor complexesThe influence of Cisplatin on the gas-phase dissociation of oligonucleotides studied by electrospray ionization tandem mass spectrometry.Evaluation of chemical mutagenicity using next generation sequencing: A review.Cisplatin downregulates BCL2L12, a novel apoptosis-related gene, in glioblastoma cells.Treatment-Induced Mutagenesis and Selective Pressures Sculpt Cancer Evolution.Bipyrimidine ruthenium(II) arene complexes: structure, reactivity and cytotoxicity.TATA binding protein discriminates between different lesions on DNA, resulting in a transcription decrease.DNA adducts of antitumor trans-[PtCl2 (E-imino ether)2].Superhelical torsion controls DNA interstrand cross-linking by antitumor cis- diamminedichloroplatinum(II)Interstrand cross-linking reaction in triplexes containing a monofunctional transplatin-adduct.Rearrangement of interstrand cross-links into intrastrand cross-links in cis-diamminedichloroplatinum(II)-modified DNA.Comment on "Delivering a photosensitive transplatin prodrug to overcome cisplatin drug resistance" by H. Song, W. Li, R. Qi, L. Yan, X. Jing, M. Zheng and H. Xiao, Chem. Commun., 2015, 51, 11493.Apoptosis induction and DNA interstrand cross-link formation by cytotoxic trans-[PtCl2(NH(CH3)2)(NHCH(CH3)2) : cross-linking between d(G) and complementary d(C) within oligonucleotide duplexes.DNA interactions of antitumor cisplatin analogs containing enantiomeric amine ligands.Chromosome-protein interactions in polyomavirus virions.
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P2860
Interstrand cross-links are preferentially formed at the d(GC) sites in the reaction between cis-diamminedichloroplatinum (II) and DNA.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on March 1991
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Interstrand cross-links are preferentially formed at the d
@nl
Interstrand cross-links are pr ...... dichloroplatinum (II) and DNA.
@en
type
label
Interstrand cross-links are preferentially formed at the d
@nl
Interstrand cross-links are pr ...... dichloroplatinum (II) and DNA.
@en
prefLabel
Interstrand cross-links are preferentially formed at the d
@nl
Interstrand cross-links are pr ...... dichloroplatinum (II) and DNA.
@en
P2093
P2860
P356
P1476
Interstrand cross-links are pr ...... dichloroplatinum (II) and DNA.
@en
P2093
P2860
P304
P356
10.1073/PNAS.88.5.1982
P407
P577
1991-03-01T00:00:00Z