The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.
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Dual role of the ddx5/ddx17 RNA helicases in the control of the pro-migratory NFAT5 transcription factorDEAD box RNA helicase functions in cancerComparative Structural Analysis of Human DEAD-Box RNA HelicasesSplicing switch of an epigenetic regulator by RNA helicases promotes tumor-cell invasivenessThe RNA helicase Ddx5/p68 binds to hUpf3 and enhances NMD of Ddx17/p72 and Smg5 mRNAThe Ddx5 and Ddx17 RNA helicases are cornerstones in the complex regulatory array of steroid hormone-signaling pathwaysHAGE (DDX43) is a biomarker for poor prognosis and a predictor of chemotherapy response in breast cancerThe RNA helicase/transcriptional co-regulator, p68 (DDX5), stimulates expression of oncogenic protein kinase, Polo-like kinase-1 (PLK1), and is associated with elevated PLK1 levels in human breast cancersAcquired dependence of acute myeloid leukemia on the DEAD-box RNA helicase DDX5.Cancer/testis antigen CAGE exerts negative regulation on p53 expression through HDAC2 and confers resistance to anti-cancer drugs.RNA helicase DDX5 regulates microRNA expression and contributes to cytoskeletal reorganization in basal breast cancer cellsPleiotropic effects of p300-mediated acetylation on p68 and p72 RNA helicase.RNA helicases in infection and disease.p68/DdX5 supports β-catenin & RNAP II during androgen receptor mediated transcription in prostate cancer.Elevated DDX21 regulates c-Jun activity and rRNA processing in human breast cancers.Signaling-mediated regulation of MicroRNA processingTranscription factor networks as targets for therapeutic intervention of cancer: the breast cancer paradigm.miRNAs regulated by estrogens, tamoxifen, and endocrine disruptors and their downstream gene targets.DDX5 regulates DNA replication and is required for cell proliferation in a subset of breast cancer cells.RBFOX1 regulates both splicing and transcriptional networks in human neuronal development.Derailed estrogen signaling and breast cancer: an authentic couple.DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functionsPrep1 and Meis1 competition for Pbx1 binding regulates protein stability and tumorigenesis.DDX5 promotes gastric cancer cell proliferation in vitro and in vivo through mTOR signaling pathwayRegulation of estrogen receptor signaling in breast carcinogenesis and breast cancer therapy.RNA helicases p68 and p72: multifunctional proteins with important implications for cancer development.P68 RNA helicase as a molecular target for cancer therapy.Genomic interaction between ER and HMGB2 identifies DDX18 as a novel driver of endocrine resistance in breast cancer cells.Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.Multi-talented DEAD-box proteins and potential tumor promoters: p68 RNA helicase (DDX5) and its paralog, p72 RNA helicase (DDX17)The RNA helicase p68 (DDX5) is selectively required for the induction of p53-dependent p21 expression and cell-cycle arrest after DNA damage.p68 RNA helicase promotes glioma cell proliferation in vitro and in vivo via direct regulation of NF-κB transcription factor p50.An evolutionarily conserved, alternatively spliced, intron in the p68/DDX5 DEAD-box RNA helicase gene encodes a novel miRNA.Extracellular superoxide dismutase and its role in cancer.Transcriptional regulation of macrophage cholesterol efflux and atherogenesis by a long noncoding RNA.Common genetic polymorphisms of microRNA biogenesis pathway genes and risk of breast cancer: a case-control study in Korea.Regulation of the U3-, U8-, and U13snoRNA Expression by the DEAD Box Proteins Ddx5/Ddx17 with Consequences for Cell Proliferation and Survival.DDX5 binds ESR1:estrogen:TFF1 gene promoter
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The DEAD-box protein p72 regulates ERalpha-/oestrogen-dependent transcription and cell growth, and is associated with improved survival in ERalpha-positive breast cancer.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 31 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
The DEAD-box protein p72 regul ...... Ralpha-positive breast cancer.
@en
The DEAD-box protein p72 regul ...... Ralpha-positive breast cancer.
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type
label
The DEAD-box protein p72 regul ...... Ralpha-positive breast cancer.
@en
The DEAD-box protein p72 regul ...... Ralpha-positive breast cancer.
@nl
prefLabel
The DEAD-box protein p72 regul ...... Ralpha-positive breast cancer.
@en
The DEAD-box protein p72 regul ...... Ralpha-positive breast cancer.
@nl
P2093
P2860
P356
P1433
P1476
The DEAD-box protein p72 regul ...... Ralpha-positive breast cancer.
@en
P2093
A M Ochocka
F V Fuller-Pace
M Periyasamy
N C Wortham
R C Coombes
R S Thomas
P2860
P2888
P304
P356
10.1038/ONC.2009.261
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P577
2009-08-31T00:00:00Z
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P6179
1052105677