PTEN: new insights into its regulation and function in skin cancer. - Wikidata - wikimedia - TriplyDB

PTEN: new insights into its regulation and function in skin cancer.

PTEN: new insights into its regulation and function in skin cancer.

http://www.wikidata.org/entity/Q37429785

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Alternative HER/PTEN/Akt pathway activation in HPV positive and negative penile carcinomas The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms.The antiproliferative response of indole-3-carbinol in human melanoma cells is triggered by an interaction with NEDD4-1 and disruption of wild-type PTEN degradation MicroRNA-21 is an important downstream component of BMP signalling in epidermal keratinocytes.The differential diagnosis of familial lentiginosis syndromes A novel tumor suppressor network in squamous malignancies FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma Basal cell carcinoma and the carcinogenic role of aberrant Hedgehog signaling.PTEN in DNA damage repair.Obesity and melanoma: exploring molecular links.MicroRNAs in skin response to UV radiation.Actin Gamma 1, a new Skin Cancer pathogenic Gene, identified by the Biological Feature-based Classification.Establishment of basal cell carcinoma animal model in Chinese tree shrew (Tupaia belangeri chinensis).Phosphoinositide 3-Kinase-Dependent Signalling Pathways in Cutaneous Squamous Cell Carcinomas.Molecular signaling cascades involved in nonmelanoma skin carcinogenesis.Inhibition of microRNA-21 upregulates the expression of programmed cell death 4 and phosphatase tensin homologue in the A431 squamous cell carcinoma cell line.Activation of AKT is associated with metastasis of nasopharyngeal carcinoma.AKT1 Activation is Obligatory for Spontaneous BCC Tumor Growth in a Murine Model that Mimics Some Features of Basal Cell Nevus Syndrome.FRA1 promotes squamous cell carcinoma growth and metastasis through distinct AKT and c-Jun dependent mechanisms.MicroRNA-22 promotes cell survival upon UV radiation by repressing PTEN.Suppression of PTEN transcription by UVA.Squamous cell carcinomas in situ arising in seborrheic keratoses: an association with concomitant immunosuppression?Distinct Role of Sesn2 in Response to UVB-Induced DNA Damage and UVA-Induced Oxidative Stress in Melanocytes.Whole genome and whole transcriptome genomic profiling of a metastatic eccrine porocarcinoma.

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PTEN: new insights into its regulation and function in skin cancer.

http://www.wikidata.org/entity/Q37429785

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 02 April 2009

@en

vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

PTEN: new insights into its regulation and function in skin cancer.

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PTEN: new insights into its regulation and function in skin cancer.

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type

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PTEN: new insights into its regulation and function in skin cancer.

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PTEN: new insights into its regulation and function in skin cancer.

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prefLabel

PTEN: new insights into its regulation and function in skin cancer.

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PTEN: new insights into its regulation and function in skin cancer.

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Journal of Investigative Dermatology

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PTEN: new insights into its regulation and function in skin cancer.

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Mei Ming

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Yu-Ying He

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The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

PTEN-deficient intestinal stem cells initiate intestinal polyposis.

Activation of a cryptic splice site of PTEN and loss of heterozygosity in benign skin lesions in Cowden disease

Conditional loss of PTEN leads to precocious development and neoplasia in the mammary gland

Ultraviolet radiation and melanoma: a systematic review and analysis of reported sequence variants

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN

Essential role for nuclear PTEN in maintaining chromosomal integrity

Germline mutations of the PTEN gene in Cowden disease, an inherited breast and thyroid cancer syndrome

Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten

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2109-2112

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10.1038/JID.2009.79

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