The structural and biochemical foundations of thiamin biosynthesis.
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Thiamin (vitamin B1) biosynthesis and regulation: a rich source of antimicrobial drug targets?Deep sequencing whole transcriptome exploration of the σE regulon in Neisseria meningitidisMechanistic and functional versatility of radical SAM enzymesThiamin biosynthesis: still yielding fascinating biological chemistryThiamin diphosphate-dependent enzymes: from enzymology to metabolic regulation, drug design and disease modelsDomain Organization in Candida glabrata THI6, a Bifunctional Enzyme Required for Thiamin Biosynthesis in Eukaryotes,A Missing Enzyme in Thiamin Thiazole Biosynthesis: Identification of TenI as a Thiazole TautomeraseStructure of trifunctional THI20 from yeastThe Last Piece in the Vitamin B1 Biosynthesis Puzzle: STRUCTURAL AND FUNCTIONAL INSIGHT INTO YEAST 4-AMINO-5-HYDROXYMETHYL-2-METHYLPYRIMIDINE PHOSPHATE (HMP-P) SYNTHASESaccharomyces cerevisiae THI4p is a suicide thiamine thiazole synthaseThiamin Pyrimidine Biosynthesis in Candida albicans: A Remarkable Reaction between Histidine and Pyridoxal PhosphateStructure of a Clostridium botulinum C143S Thiaminase I/Thiamin Complex Reveals Active Site Architecture,Structure of a eukaryotic thiaminase ICo-opting sulphur-carrier proteins from primary metabolic pathways for 2-thiosugar biosynthesisHigh-resolution crystal structure of the eukaryotic HMP-P synthase (THIC) from Arabidopsis thalianaStructure-based design of potent small-molecule binders to the S-component of the ECF transporter for thiamineA cross-kingdom Nudix enzyme that pre-empts damage in thiamin metabolism.Does Abiotic Stress Cause Functional B Vitamin Deficiency in Plants?Swimming in light: a large-scale computational analysis of the metabolism of Dinoroseobacter shibaeMetagenome survey of a multispecies and alga-associated biofilm revealed key elements of bacterial-algal interactions in photobioreactorsNon-canonical active site architecture of the radical SAM thiamin pyrimidine synthaseVitamin B1 in marine sediments: pore water concentration gradient drives benthic flux with potential biological implications.Mobile genetic element proliferation and gene inactivation impact over the genome structure and metabolic capabilities of Sodalis glossinidius, the secondary endosymbiont of tsetse flies.The vitamin B1 metabolism of Staphylococcus aureus is controlled at enzymatic and transcriptional levels.Comparative transcriptome analysis of four prymnesiophyte algae.A biosynthetic pathway for BE-7585A, a 2-thiosugar-containing angucycline-type natural product.Thiamine metabolism is critical for regulating correlated growth of dendrite arbors and neuronal somata.Mechanistic studies of the biosynthesis of 2-thiosugar: evidence for the formation of an enzyme-bound 2-ketohexose intermediate in BexX-catalyzed reactionGenetic diversity within the genus Francisella as revealed by comparative analyses of the genomes of two North American isolates from environmental sources.Conserved active site cysteine residue of archaeal THI4 homolog is essential for thiamine biosynthesis in Haloferax volcanii.Adenosyl radical: reagent and catalyst in enzyme reactions.Alternatives to vitamin B1 uptake revealed with discovery of riboswitches in multiple marine eukaryotic lineages.Computational identification of novel biochemical systems involved in oxidation, glycosylation and other complex modifications of bases in DNA.Analysis of the Aspergillus fumigatus proteome reveals metabolic changes and the activation of the pseurotin A biosynthesis gene cluster in response to hypoxia.Quantitative genome-wide genetic interaction screens reveal global epistatic relationships of protein complexes in Escherichia coliCommon ancestry and novel genetic traits of Francisella novicida-like isolates from North America and Australia as revealed by comparative genomic analyses.The rhodanese domain of ThiI is both necessary and sufficient for synthesis of the thiazole moiety of thiamine in Salmonella entericaSystematic genome assessment of B-vitamin biosynthesis suggests co-operation among gut microbes.Functional Diversity of Haloacid Dehalogenase Superfamily Phosphatases from Saccharomyces cerevisiae: BIOCHEMICAL, STRUCTURAL, AND EVOLUTIONARY INSIGHTS.Imaging metabolite dynamics in living cells using a Spinach-based riboswitch.
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The structural and biochemical foundations of thiamin biosynthesis.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on January 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
The structural and biochemical foundations of thiamin biosynthesis.
@en
The structural and biochemical foundations of thiamin biosynthesis.
@nl
type
label
The structural and biochemical foundations of thiamin biosynthesis.
@en
The structural and biochemical foundations of thiamin biosynthesis.
@nl
prefLabel
The structural and biochemical foundations of thiamin biosynthesis.
@en
The structural and biochemical foundations of thiamin biosynthesis.
@nl
P2860
P1476
The structural and biochemical foundations of thiamin biosynthesis.
@en
P2093
Christopher T Jurgenson
Tadhg P Begley
P2860
P304
P356
10.1146/ANNUREV.BIOCHEM.78.072407.102340
P577
2009-01-01T00:00:00Z