Nuance in the double-helix and its role in protein-DNA recognition.
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The role of DNA shape in protein-DNA recognitionDNA dynamics and single-molecule biologyTowards structural systems pharmacology to study complex diseases and personalized medicineSequence-specific ultrasonic cleavage of DNAElectronic structure and dynamics of nitrosyl porphyrinsIntrinsic flexibility of B-DNA: the experimental TRX scale.Gene expression divergence is coupled to evolution of DNA structure in coding regions.Absence of a simple code: how transcription factors read the genomeElectrostatic interactions between arginines and the minor groove in the nucleosome.A combination of computational and experimental approaches identifies DNA sequence constraints associated with target site binding specificity of the transcription factor CSL.Deconvolving the recognition of DNA shape from sequence.Operator recognition by the ROK transcription factor family members, NagC and MlcEvolving insights on how cytosine methylation affects protein-DNA binding.DNA shape, genetic codes, and evolutionUsing a structural and logics systems approach to infer bHLH-DNA binding specificity determinants.Genome-wide analysis of transcription factor binding sites and their characteristic DNA structures.do_x3dna: a tool to analyze structural fluctuations of dsDNA or dsRNA from molecular dynamics simulations.Origins of specificity in protein-DNA recognition.Functional interplay between the RK motif and linker segment dictates Oct4-DNA recognition.Sequence-Specific Recognition of DNA by Proteins: Binding Motifs Discovered Using a Novel Statistical/Computational Analysis.Probing DNA shape and methylation state on a genomic scale with DNase I.High-resolution biophysical analysis of the dynamics of nucleosome formationEvaluation of novel design strategies for developing zinc finger nucleases tools for treating human diseases.The DNA and RNA sugar-phosphate backbone emerges as the key player. An overview of quantum-chemical, structural biology and simulation studies.Quantitative characterization of conformational-specific protein-DNA binding using a dual-spectral interferometric imaging biosensor.Proteins Recognizing DNA: Structural Uniqueness and Versatility of DNA-Binding Domains in Stem Cell Transcription Factors.Statistical investigation of position-specific deformation pattern of nucleosome DNA based on multiple conformational properties.Quantitative Analysis of Protein-DNA Interaction by qDPI-ELISA.Investigation of arc repressor DNA-binding specificity by comparative molecular dynamics simulations.Statistical analysis of structural determinants for protein-DNA-binding specificity.Specific minor groove solvation is a crucial determinant of DNA binding site recognitionNitroxide sensing of a DNA microenvironment: mechanistic insights from EPR spectroscopy and molecular dynamics simulations.A flexible integrative approach based on random forest improves prediction of transcription factor binding sites.Search by proteins for their DNA target site: 1. The effect of DNA conformation on protein sliding.DNAshape: a method for the high-throughput prediction of DNA structural features on a genomic scale.Searching target sites on DNA by proteins: Role of DNA dynamics under confinement.Sequence-specific transitions of the torsion angle gamma change the polar-hydrophobic profile of the DNA grooves: implication for indirect protein-DNA recognition.Zinc finger protein binding to DNA: an energy perspective using molecular dynamics simulation and free energy calculations on mutants of both zinc finger domains and their specific DNA bases.Genome-wide prediction of minor-groove electrostatic potential enables biophysical modeling of protein-DNA binding.Expanding the repertoire of DNA shape features for genome-scale studies of transcription factor binding.
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P2860
Nuance in the double-helix and its role in protein-DNA recognition.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 10 April 2009
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vedecký článok
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vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Nuance in the double-helix and its role in protein-DNA recognition.
@en
Nuance in the double-helix and its role in protein-DNA recognition.
@nl
type
label
Nuance in the double-helix and its role in protein-DNA recognition.
@en
Nuance in the double-helix and its role in protein-DNA recognition.
@nl
prefLabel
Nuance in the double-helix and its role in protein-DNA recognition.
@en
Nuance in the double-helix and its role in protein-DNA recognition.
@nl
P2093
P2860
P1476
Nuance in the double-helix and its role in protein-DNA recognition
@en
P2093
P2860
P304
P356
10.1016/J.SBI.2009.03.002
P50
P577
2009-04-10T00:00:00Z