The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence - Wikidata - wikimedia - TriplyDB

The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence

The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence

http://www.wikidata.org/entity/Q37444372

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Adipose tissue as an immunological organ Drivers of age-related inflammation and strategies for healthspan extension Canonical Nlrp3 inflammasome links systemic low-grade inflammation to functional decline in aging.Prolongevity hormone FGF21 protects against immune senescence by delaying age-related thymic involution Deep tissue injury in development of pressure ulcers: a decrease of inflammasome activation and changes in human skin morphology in response to aging and mechanical load.Sphingolipid metabolites in inflammatory disease.The transcription factor NR4A1 is essential for the development of a novel macrophage subset in the thymus.Young, proliferative thymic epithelial cells engraft and function in aging thymuses.IL-18 acts in synergy with IL-7 to promote ex vivo expansion of T lymphoid progenitor cells.Inhibition of B Lymphopoiesis by Adipocytes and IL-1-Producing Myeloid-Derived Suppressor Cells Severe Changes in Thymic Microenvironment in a Chronic Experimental Model of Paracoccidioidomycosis ROS-Mediated NLRP3 Inflammasome Activity Is Essential for Burn-Induced Acute Lung Injury Bone marrow fat and the decline of B lymphopoiesis in rabbits Modular transcriptional repertoire and MicroRNA target analyses characterize genomic dysregulation in the thymus of Down syndrome infants.Chronic caloric restriction partially protects against age-related alteration in serum metabolome IL-18BP is decreased in osteoporotic women: Prevents Inflammasome mediated IL-18 activation and reduces Th17 differentiation.New roles of HDL in inflammation and hematopoiesis.Candida albicans triggers NLRP3-mediated pyroptosis in macrophages.Quantification of adipose tissue leukocytosis in obesity.Mitochondrial dysfunction and oxidative stress activate inflammasomes: impact on the aging process and age-related diseases.Epigenetic regulation of ASC/TMS1 expression: potential role in apoptosis and inflammasome function.Molecular regulation of cell fate in cerebral ischemia: role of the inflammasome and connected pathways.Ageing, adipose tissue, fatty acids and inflammation.NLRP3 at the interface of metabolism and inflammation.Immune ageing and susceptibility to Streptococcus pneumoniae.Lymphopaenia in cardiac arrest patients.Development and developmental potential of cortical thymic epithelial cells.Mitochondria and the NLRP3 inflammasome: physiological and pathological relevance.Inflammasomes and intestinal inflammation.Thymic Atrophy: Experimental Studies and Therapeutic Interventions.Global transcriptional profiling reveals distinct functions of thymic stromal subsets and age-related changes during thymic involution.Immunological complications of obesity.Age-associated alterations in the levels of cytotoxic lipid molecular species and oxidative stress in the murine thymus are reduced by growth hormone treatment.Thymic stromal cells: Roles in atrophy and age-associated dysfunction of the thymus.Interferon-γ- and glucocorticoid-mediated pathways synergize to enhance death of CD4(+) CD8(+) thymocytes during Salmonella enterica serovar Typhimurium infection.Growth Hormone Receptor Deficiency Protects against Age-Related NLRP3 Inflammasome Activation and Immune Senescence.Inflammatory Changes in Bone Marrow Microenvironment Associated with Declining B Lymphopoiesis.Immunomodulatory Function of Myeloid-Derived Suppressor Cells during B Cell-Mediated Immune Responses.Inflammation: Bridging Age, Menopause and APOEε4 Genotype to Alzheimer's Disease

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The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence

http://www.wikidata.org/entity/Q37444372

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article científic

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bilimsel makale

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scientific article published on 26 January 2012

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence

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The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence.

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The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence

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The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence.

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The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence

@en

The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence.

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J.CELREP.2011.11.005

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The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence

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Anthony Ravussin

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Ayinuer Adijiang

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Bolormaa Vandanmagsar

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John S Owen

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John S Parks

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Joseph Francis

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Michael J Thomas

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Vishwa Deep Dixit

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Xuewei Zhu

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Yun-Hee Youm

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P2860

Ghrelin inhibits leptin- and activation-induced proinflammatory cytokine expression by human monocytes and T cells

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

A simple method for the isolation and purification of total lipides from animal tissues

Aging up-regulates expression of inflammatory mediators in mouse adipose tissue

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

Reduction in the developmental potential of intrathymic T cell progenitors with age

Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme

Cryopyrin activates the inflammasome in response to toxins and ATP

Thioredoxin-interacting protein links oxidative stress to inflammasome activation

Critical role for NALP3/CIAS1/Cryopyrin in innate and adaptive immunity through its regulation of caspase-1

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56-68

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scholarly article

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10.1016/J.CELREP.2011.11.005

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1

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1

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Thirumala-Devi Kanneganti

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230567595

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