Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis - Wikidata - wikimedia - TriplyDB

Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis

Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis

http://www.wikidata.org/entity/Q37446488

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Overexpression of Cancer-Associated Genes via Epigenetic Derepression Mechanisms in Gynecologic Cancer Links between Human LINE-1 Retrotransposons and Hepatitis Virus-Related Hepatocellular Carcinoma Physiological and pathological implications of 5-hydroxymethylcytosine in diseases DNA Methylation Analysis: Choosing the Right Method Crossing the LINE Toward Genomic Instability: LINE-1 Retrotransposition in Cancer The Fine LINE: Methylation Drawing the Cancer Landscape Response of transposable elements to environmental stressors SVA retrotransposons as potential modulators of neuropeptide gene expression Endogenous retroviral promoter exaptation in human cancer Whole-genome analysis of papillary kidney cancer finds significant noncoding alterations 5-Methylcytosine hydroxylation-mediated LINE-1 hypomethylation: a novel mechanism of proto-oncogenes activation in colorectal cancer?Modulation of microRNA expression in human lung cancer cells by the G9a histone methyltransferase inhibitor BIX01294.Prognostic significance of LINE-1 hypomethylation in oropharyngeal squamous cell carcinoma.Methylation Levels of LINE-1 As a Useful Marker for Venous Invasion in Both FFPE and Frozen Tumor Tissues of Gastric Cancer LINE-1 hypomethylation is not a common event in preneoplastic stages of gastric carcinogenesis.DNA methylome profiling identifies novel methylated genes in African American patients with colorectal neoplasia IGF2 differentially methylated region hypomethylation in relation to pathological and molecular features of serrated lesions.LINE-1 hypomethylation in blood and tissue samples as an epigenetic marker for cancer risk: a systematic review and meta-analysis.Epigenetic Alterations in Colorectal Cancer: Emerging Biomarkers.Chromatin Memory in the Development of Human Cancers Promoter hypermethylation of tumour suppressor genes as potential biomarkers in colorectal cancer.DNA methylation, microRNAs, and their crosstalk as potential biomarkers in hepatocellular carcinoma.Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.MicroRNA-29c mediates initiation of gastric carcinogenesis by directly targeting ITGB1.LINE-1 Methylation Status Correlates Significantly to Post-Therapeutic Recurrence in Stage III Colon Cancer Patients Receiving FOLFOX-4 Adjuvant Chemotherapy Onco-exaptation of an endogenous retroviral LTR drives IRF5 expression in Hodgkin lymphoma.Epigenetic changes and alternate promoter usage by human colon cancers for expressing DCLK1-isoforms: Clinical Implications Assessing the potential value of long interspersed element-1 hypomethylation in colorectal cancer: evidence from retrospective studies Transposable Elements in Human Cancer: Causes and Consequences of Deregulation Aberrant DNA methylation profiles of inherited and sporadic colorectal cancer.Gene-specific DNA methylation profiles and LINE-1 hypomethylation are associated with myocardial infarction risk.The molecular pathogenesis of colorectal cancer and its potential application to colorectal cancer screening Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart The impact of chromosomal translocation locus and fusion oncogene coding sequence in synovial sarcomagenesis Integrated epigenomic analyses of enhancer as well as promoter regions in gastric cancer.Epigenetic status of LINE-1 predicts clinical outcome in early-stage rectal cancer.Genetic and epigenetic biomarkers for diagnosis, prognosis and treatment of colorectal cancer LINE1 and Alu repetitive element DNA methylation in tumors and white blood cells from epithelial ovarian cancer patients.LINE-1 is preferentially hypomethylated within adenomatous polyps in the presence of synchronous colorectal cancer.The dynamic DNA methylation landscape of the mutL homolog 1 shore is altered by MLH1-93G>A polymorphism in normal tissues and colorectal cancer.

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Hypomethylation of long interspersed nuclear element-1 (LINE-1) leads to activation of proto-oncogenes in human colorectal cancer metastasis

http://www.wikidata.org/entity/Q37446488

description

article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 23 May 2013

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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name

Hypomethylation of long inters ...... n colorectal cancer metastasis

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Hypomethylation of long interspersed nuclear element-1

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type

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Hypomethylation of long inters ...... n colorectal cancer metastasis

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Hypomethylation of long interspersed nuclear element-1

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prefLabel

Hypomethylation of long inters ...... n colorectal cancer metastasis

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Hypomethylation of long interspersed nuclear element-1

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Hypomethylation of long inters ...... n colorectal cancer metastasis

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C Richard Boland

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Emilio Burgos

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Jaime Feliu

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Paloma Cejas

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P2860

Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot project

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

The cancer-related protein SSX2 interacts with the human homologue of a Ras-like GTPase interactor, RAB3IP, and a novel nuclear protein, SSX2IP

Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2

The presence of 5-hydroxymethylcytosine in animal deoxyribonucleic acid

Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes

Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

The epigenomics of cancer

Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

The behaviour of 5-hydroxymethylcytosine in bisulfite sequencing

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635-646

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scholarly article

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10.1136/GUTJNL-2012-304219

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4

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63

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Juan Moreno-Rubio

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2013-05-23T00:00:00Z

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23704319

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colorectal cancer

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3884067

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