iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.

iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.

Item

http://www.wikidata.org/entity/Q37447788

Q37447788

about

Structure and Mechanism of the trans -Acting Acyltransferase from the Disorazole Synthase Vinylogous chain branching catalysed by a dedicated polyketide synthase module Genomic and Secondary Metabolite Analyses of Streptomyces sp. 2AW Provide Insight into the Evolution of the Cycloheximide Pathway C-S bond cleavage by a polyketide synthase domain.Oxazolomycin biosynthesis in Streptomyces albus JA3453 featuring an "acyltransferase-less" type I polyketide synthase that incorporates two distinct extender units Synthesis and evaluation of antimigratory and antiproliferative activities of lipid-linked [13]-macro-dilactones Improvement of natamycin production by engineering of phosphopantetheinyl transferases in Streptomyces chattanoogensis L10.Comparative characterization of the lactimidomycin and iso-migrastatin biosynthetic machineries revealing unusual features for acyltransferase-less type I polyketide synthases and providing an opportunity to engineer new analogues.Cycloheximide and actiphenol production in Streptomyces sp. YIM56141 governed by single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.Structural and evolutionary relationships of "AT-less" type I polyketide synthase ketosynthases Overproduction of lactimidomycin by cross-overexpression of genes encoding Streptomyces antibiotic regulatory proteins.Improvement of secondary metabolite production in Streptomyces by manipulating pathway regulation Boronated tartrolon antibiotic produced by symbiotic cellulose-degrading bacteria in shipworm gills.Progress challenges and opportunities for the re-engineering of trans-AT polyketide synthases.Polyketide biosynthesis in dinoflagellates: what makes it different?A Long-Range Acting Dehydratase Domain as the Missing Link for C17-Dehydration in Iso-Migrastatin Biosynthesis.Post-polyketide synthase steps in iso-migrastatin biosynthesis, featuring tailoring enzymes with broad substrate specificity.Cyclization of polyketides and non-ribosomal peptides on and off their assembly lines.Biosynthesis of polyketides by trans-AT polyketide synthases.Polyketide synthase chimeras reveal key role of ketosynthase domain in chain branching.Sigma factor WhiGch positively regulates natamycin production in Streptomyces chattanoogensis L10.Genome mining-directed activation of a silent angucycline biosynthetic gene cluster in Streptomyces chattanoogensis.Enzymatic polyketide chain branching to give substituted lactone, lactam, and glutarimide heterocycles.Titer improvement of iso-migrastatin in selected heterologous Streptomyces hosts and related analysis of mRNA expression by quantitative RT-PCR.Iso-migrastatin Titer Improvement in the Engineered Streptomyces lividans SB11002 Strain by Optimization of Fermentation Conditions.A new glutarimide derivative from marine sponge-derived Streptomyces anulatus S71.

P2860

Q27670570-0CE5589D-8972-4FAC-8F00-4D4BA0B1CEAF Q27686712-1FA9C33E-36BC-49D4-8A76-D1FDA15CD249 Q28833700-3C239756-A8B8-4E07-908A-339234235E82 Q30984909-EF5F42AD-01DC-47EA-ABEB-136DA0598549 Q33924378-C7F6B7F2-6CAD-4AA4-AFC5-11B3FE5B3C21 Q34091813-3AE3D6ED-F81D-480C-8053-57F7ED7264B7 Q34335001-613D35CC-DBC6-49F8-B779-4D61A10DBFE6 Q34731577-844D54D4-7511-4373-A1FD-C8A81E7BBC51 Q35166245-365ECD34-57D4-473C-B445-9590EE1136B4 Q35792961-40BBA33F-8701-44A1-A355-0B91F30E35EE Q35836514-4742E852-15EC-40C4-96E8-C5F73C2BEB80 Q36321025-F94FECF5-A54B-494F-BCE0-6682F6B22103 Q36567765-D0EC1892-8117-4D76-AAD3-E0E1D5524B8E Q38189999-1AB37133-E846-4A6F-AF69-A9A9C8CC4317 Q38220326-A8AC9DF6-BA18-4576-AE56-02287CDA25B2 Q38431532-983B66B4-1560-488F-AEE1-CBE01FF10681 Q38455473-5A96D4A8-47ED-4191-9F16-5A6A96B0DB9C Q38646975-9831630B-CEA8-4C21-AF68-0349388AD61F Q38675125-4AF47A59-CD1A-42F5-98B3-333AE49342EF Q40946592-090C8854-3233-4B36-8B13-77998650BEF4 Q41338359-C8281856-3923-414A-AC73-7FC40C04A49F Q41685802-2511E78C-05D0-44FE-8F6D-2C4360ADD2D4 Q41741898-8882008C-6A60-461C-87E4-430EC7163EEB Q41778906-8B56ADB7-CA2A-4D75-B02A-FB962683A73F Q42738348-AC967157-41BF-4E19-BB98-CA4638C57E04 Q51435086-4A02EBAF-3D82-4F58-A0FB-D4ECE7C5CE84

P2860

iso-Migrastatin, migrastatin, and dorrigocin production in Streptomyces platensis NRRL 18993 is governed by a single biosynthetic machinery featuring an acyltransferase-less type I polyketide synthase.

Item

http://www.wikidata.org/entity/Q37447788

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 02 September 2009

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs