Impaired immune responses in the lungs of aged mice following influenza infection.
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Modeling Influenza Virus Infection: A Roadmap for Influenza ResearchThe Impact of Immunosenescence on Pulmonary DiseaseAge-dependent dysregulation of innate immunityEarly priming minimizes the age-related immune compromise of CD8⁺ T cell diversity and functionInnate immune responses in the ageing lung.Diverse heterologous primary infections radically alter immunodominance hierarchies and clinical outcomes following H7N9 influenza challenge in miceInfluenza A virus infection kinetics: quantitative data and models.CD8+ T cell immunity to 2009 pandemic and seasonal H1N1 influenza virusesAge-related sensitivity and pathological differences in infections by 2009 pandemic influenza A (H1N1) virusA computationally optimized broadly reactive antigen (COBRA) based H5N1 VLP vaccine elicits broadly reactive antibodies in mice and ferretsElicitation of anti-1918 influenza virus immunity early in life prevents morbidity and lower levels of lung infection by 2009 pandemic H1N1 influenza virus in aged mice.Aging of the CD4 T Cell Compartment.Vaccination with DNA plasmids expressing Gn coupled to C3d or alphavirus replicons expressing gn protects mice against Rift Valley fever virus.Aging-associated dysregulation of homeostatic immune response termination (and not initiation).Aging reduces the expression of lung CINC and MCP-1 mRNA in a P. aeruginosa rat model of infection.Aging of the innate immune systemImpact of ageing on the response and repertoire of influenza virus-specific CD4 T cells.Large scale comparison of innate responses to viral and bacterial pathogens in mouse and macaque.The interferon-induced gene Ifi27l2a is active in lung macrophages and lymphocytes after influenza A infection but deletion of Ifi27l2a in mice does not increase susceptibility to infection.Aging exacerbates damage and delays repair of alveolar epithelia following influenza viral pneumonia.A large-scale immuno-epidemiological simulation of influenza A epidemicsGlobal transcriptome analysis in influenza-infected mouse lungs reveals the kinetics of innate and adaptive host immune responses.Impact of aging on viral infections.Evasion of natural killer cells by influenza virus.Defective interfering virus protects elderly mice from influenzaNrf2 expression modifies influenza A entry and replication in nasal epithelial cells.Independent association of younger age with hemoptysis in adults with pulmonary tuberculosisEpithelial cells from smokers modify dendritic cell responses in the context of influenza infection.Natural killer cell function is altered during the primary response of aged mice to influenza infection.Age-related increases in PGD(2) expression impair respiratory DC migration, resulting in diminished T cell responses upon respiratory virus infection in mice.The inflammatory response to influenza A virus (H1N1): An experimental and mathematical study.Potential role for alternatively activated macrophages in the secondary bacterial infection during recovery from influenza.Oral Wild-Type Salmonella Typhi Challenge Induces Activation of Circulating Monocytes and Dendritic Cells in Individuals Who Develop Typhoid Disease.Antibody breadth and protective efficacy are increased by vaccination with computationally optimized hemagglutinin but not with polyvalent hemagglutinin-based H5N1 virus-like particle vaccines.Impaired NLRP3 inflammasome function in elderly mice during influenza infection is rescued by treatment with nigericin.T-cell biology in aging, with a focus on lung disease.Tissue exit: a novel control point in the accumulation of antigen-specific CD8 T cells in the influenza a virus-infected lung.Immunosenescence and Challenges of Vaccination against Influenza in the Aging Population.CpG Improves Influenza Vaccine Efficacy in Young Adult but Not Aged Mice.Plasmacytoid dendritic cell depletion leads to an enhanced mononuclear phagocyte response in lungs of mice with lethal influenza virus infection
P2860
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P2860
Impaired immune responses in the lungs of aged mice following influenza infection.
description
2009 nî lūn-bûn
@nan
2009年の論文
@ja
2009年学术文章
@wuu
2009年学术文章
@zh-cn
2009年学术文章
@zh-hans
2009年学术文章
@zh-my
2009年学术文章
@zh-sg
2009年學術文章
@yue
2009年學術文章
@zh
2009年學術文章
@zh-hant
name
Impaired immune responses in the lungs of aged mice following influenza infection.
@en
Impaired immune responses in the lungs of aged mice following influenza infection.
@nl
type
label
Impaired immune responses in the lungs of aged mice following influenza infection.
@en
Impaired immune responses in the lungs of aged mice following influenza infection.
@nl
prefLabel
Impaired immune responses in the lungs of aged mice following influenza infection.
@en
Impaired immune responses in the lungs of aged mice following influenza infection.
@nl
P2860
P356
P1433
P1476
Impaired immune responses in the lungs of aged mice following influenza infection.
@en
P2093
Franklin R Toapanta
Ted M Ross
P2860
P2888
P356
10.1186/1465-9921-10-112
P577
2009-11-18T00:00:00Z
P5875
P6179
1031092148