Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1.
about
A variant upstream of IFNL3 (IL28B) creating a new interferon gene IFNL4 is associated with impaired clearance of hepatitis C virusGenetic variants at the IFNL3 locus and their association with hepatitis C virus infections reveal novel insights into host-virus interactionsInterferon lambda polymorphisms associate with body iron indices and hepatic expression of interferon-responsive long non-coding RNA in chronic hepatitis C.Early viral kinetics during hepatitis C virus genotype 6 treatment according to IL28B polymorphismsClinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for IFNL3 (IL28B) genotype and PEG interferon-α-based regimens.Test of IL28B polymorphisms in chronic hepatitis C patients treated with PegIFN and ribavirin depends on HCV genotypes: results from a meta-analysis.Meta-analysis: implications of interleukin-28B polymorphisms in spontaneous and treatment-related clearance for patients with hepatitis C.Host genetic variants in the pathogenesis of hepatitis C.High effectiveness of peginterferon alfa-2a plus ribavirin therapy in Korean patients with chronic hepatitis C in clinical practice.IFNL3 genotype is associated with differential induction of IFNL3 in primary human hepatocytes.Understanding triphasic HCV decline during treatment in the era of IL28B polymorphisms and direct acting antiviral agents via mathematical modelingOptimum ribavirin exposure overcomes racial disparity in efficacy of peginterferon and ribavirin treatment for hepatitis C genotype 1.SNP rs8099917 in gene IL28B might be associated with risk of chronic infection by HCV but not with response to treatment.Individualization of chronic hepatitis C treatment according to the host characteristics.Introduction to the genetics and biology of interleukin-28B.Interleukin 28B polymorphisms as predictors of sustained virological response in chronic hepatitis C: systematic review and meta-analysis.IFN-λ gene polymorphisms as predictive factors in chronic hepatitis C treatment-naive patients without access to protease inhibitors.Early predictors of antiviral treatment response in liver transplant recipients with recurrent hepatitis C genotype 1.
P2860
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P2860
Single nucleotide polymorphism upstream of interleukin 28B associated with phase 1 and phase 2 of early viral kinetics in patients infected with HCV genotype 1.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 23 October 2011
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
Single nucleotide polymorphism ...... infected with HCV genotype 1.
@en
Single nucleotide polymorphism ...... infected with HCV genotype 1.
@nl
type
label
Single nucleotide polymorphism ...... infected with HCV genotype 1.
@en
Single nucleotide polymorphism ...... infected with HCV genotype 1.
@nl
prefLabel
Single nucleotide polymorphism ...... infected with HCV genotype 1.
@en
Single nucleotide polymorphism ...... infected with HCV genotype 1.
@nl
P2093
P2860
P50
P1476
Single nucleotide polymorphism ...... infected with HCV genotype 1.
@en
P2093
Alexander J Thompson
Alexis Gorden
Chadi Ibrahim
Charles D Howell
David B Goldstein
John G McHutchison
Kathleen A Ryan
Kevin V Shianna
Michael Fried
P2860
P304
P356
10.1016/J.JHEP.2011.10.004
P577
2011-10-23T00:00:00Z