Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.
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Crosstalk of HNF4α with extracellular and intracellular signaling pathways in the regulation of hepatic metabolism of drugs and lipidsChemoprotective epigenetic mechanisms in a colorectal cancer model: Modulation by n-3 PUFA in combination with fermentable fiberOrganic anion and cation SLC22 "drug" transporter (Oat1, Oat3, and Oct1) regulation during development and maturation of the kidney proximal tubuleGenetics and pathogenesis of inflammatory bowel diseaseSrc tyrosine kinase phosphorylation of nuclear receptor HNF4α correlates with isoform-specific loss of HNF4α in human colon cancer.Obesity, rather than diet, drives epigenomic alterations in colonic epithelium resembling cancer progression.Chromatin profiling reveals regulatory network shifts and a protective role for hepatocyte nuclear factor 4α during colitis.Nuclear receptor HNF4α binding sequences are widespread in Alu repeatsIntestinal development and differentiation.Vertebrate intestinal endoderm development.Early insights into the function of KIAA1199, a markedly overexpressed protein in human colorectal tumors.Analysis of gene-environment interactions in postnatal development of the mammalian intestine.Claudin-2 as a mediator of leaky gut barrier during intestinal inflammation.An HNF4α-miRNA inflammatory feedback circuit regulates hepatocellular oncogenesisAmelioration of diabesity-induced colorectal ontogenesis by omega-3 fatty acids in mice.Differential Effects of Hepatocyte Nuclear Factor 4α Isoforms on Tumor Growth and T-Cell Factor 4/AP-1 Interactions in Human Colorectal Cancer Cells.Identification of five novel modifier loci of Apc(Min) harbored in the BXH14 recombinant inbred strain.HNF4α is a therapeutic target that links AMPK to WNT signalling in early-stage gastric cancer.HNF4α: a new biomarker in colon cancer?Transcriptional Regulation of X-Box-binding Protein One (XBP1) by Hepatocyte Nuclear Factor 4α (HNF4Α) Is Vital to Beta-cell FunctionHepatocyte nuclear factor 1 coordinates multiple processes in a model of intestinal epithelial cell function.The Drosophila HNF4 nuclear receptor promotes glucose-stimulated insulin secretion and mitochondrial function in adultsOpposing roles of nuclear receptor HNF4α isoforms in colitis and colitis-associated colon cancer.Nkx2-1 represses a latent gastric differentiation program in lung adenocarcinoma.Claudin-based barrier differentiation in the colonic epithelial crypt niche involves Hopx/Klf4 and Tcf7l2/Hnf4-α cascadesNutrient-Gene Interaction in Colon Cancer, from the Membrane to Cellular Physiology.Regulation of hepatic microRNA expression by hepatocyte nuclear factor 4 alpha.Genetics of ulcerative colitis.Molecular mechanisms of Barrett's esophagus.Current and emerging approaches to define intestinal epithelium-specific transcriptional networks.The orphan nuclear receptors at their 25-year reunion.Hepatocyte nuclear factor 4-alpha involvement in liver and intestinal inflammatory networksHepatocyte nuclear factor 4α is required for cell differentiation and homeostasis in the adult mouse gastric epithelium.Polarisation and functional characterisation of hepatocytes derived from human embryonic and mesenchymal stem cells.Hepatocyte nuclear factor 4α suppresses the aggravation of colon carcinoma.Wnt and Notch signals guide embryonic stem cell differentiation into the intestinal lineages.Layered defense: how mucus and tight junctions seal the intestinal barrier.Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling.Reelin is involved in the crypt-villus unit homeostasis.Association between genetic variants in the HNF4A gene and childhood-onset Crohn's disease.
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Hepatocyte nuclear factor 4alpha, a key factor for homeostasis, cell architecture, and barrier function of the adult intestinal epithelium.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 05 October 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Hepatocyte nuclear factor 4alp ...... e adult intestinal epithelium.
@en
Hepatocyte nuclear factor 4alp ...... e adult intestinal epithelium.
@nl
type
label
Hepatocyte nuclear factor 4alp ...... e adult intestinal epithelium.
@en
Hepatocyte nuclear factor 4alp ...... e adult intestinal epithelium.
@nl
prefLabel
Hepatocyte nuclear factor 4alp ...... e adult intestinal epithelium.
@en
Hepatocyte nuclear factor 4alp ...... e adult intestinal epithelium.
@nl
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P2860
P50
P356
P1476
Hepatocyte nuclear factor 4alp ...... he adult intestinal epithelium
@en
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Agnès Ribeiro
Anne-Laure Cattin
Frank J Gonzalez
Martine Pinçon-Raymond
Michel Lacasa
Philippe Cardot
Susan Saint-Just
Sylvie Robine
P2860
P304
P356
10.1128/MCB.00939-09
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P577
2009-10-05T00:00:00Z