Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.
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Replicon RNA Viral Vectors as VaccinesCombining antiangiogenic therapy with immunotherapy exerts better therapeutical effects on large tumors in a woodchuck hepatoma modelThe third signal cytokine IL-12 rescues the anti-viral function of exhausted HBV-specific CD8 T cellsElectroporation enhances immunogenicity of a DNA vaccine expressing woodchuck hepatitis virus surface antigen in woodchucks.Neoadjuvant administration of Semliki Forest virus expressing interleukin-12 combined with attenuated Salmonella eradicates breast cancer metastasis and achieves long-term survival in immunocompetent mice.Immunotherapeutic synergy between anti-CD137 mAb and intratumoral administration of a cytopathic Semliki Forest virus encoding IL-12.Prevention of liver tumor formation in woodchucks with established hepatocellular carcinoma by treatment with cationic liposome-DNA complexesVirotherapy, gene transfer and immunostimulatory monoclonal antibodies.Gene therapy approaches against cancer using in vivo and ex vivo gene transfer of interleukin-12.Semliki Forest virus biodistribution in tumor-free and 4T1 mammary tumor-bearing mice: a comparison of transgene delivery by recombinant virus particles and naked RNA replicon.A Semliki forest virus vector engineered to express IFNα induces efficient elimination of established tumors.Therapeutic vaccination in chronic hepatitis B: preclinical studies in the woodchuck.Generation and Functional In Vitro Analysis of Semliki Forest Virus Vectors Encoding TNF-α and IFN-γ.Modulators of innate immunity as novel therapeutics for treatment of chronic hepatitis B.Gene Therapy for Chronic HBV-Can We Eliminate cccDNA?
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P2860
Semliki forest virus expressing interleukin-12 induces antiviral and antitumoral responses in woodchucks with chronic viral hepatitis and hepatocellular carcinoma.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 09 September 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
@cs
name
Semliki forest virus expressin ...... and hepatocellular carcinoma.
@en
Semliki forest virus expressin ...... and hepatocellular carcinoma.
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type
label
Semliki forest virus expressin ...... and hepatocellular carcinoma.
@en
Semliki forest virus expressin ...... and hepatocellular carcinoma.
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prefLabel
Semliki forest virus expressin ...... and hepatocellular carcinoma.
@en
Semliki forest virus expressin ...... and hepatocellular carcinoma.
@nl
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P2860
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Semliki forest virus expressin ...... s and hepatocellular carcinoma
@en
P2093
Bud C Tennant
Christine A Bellezza
Gloria González-Aseguinolaza
Jose I Quetglas
Julien Crettaz
Katherine H Liu
Marta Ruiz-Guillen
Nathan L Dykes
Scott D Butler
Stephan Menne
P2860
P304
12266-12278
P356
10.1128/JVI.01597-09
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P577
2009-09-09T00:00:00Z