Expression of the human cytomegalovirus UL97 gene in a chimeric guinea pig cytomegalovirus (GPCMV) results in viable virus with increased susceptibility to ganciclovir and maribavir.
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Cytomegalovirus antivirals and development of improved animal modelsViral Glycoprotein Complex Formation, Essential Function and Immunogenicity in the Guinea Pig Model for CytomegalovirusA Homolog Pentameric Complex Dictates Viral Epithelial Tropism, Pathogenicity and Congenital Infection Rate in Guinea Pig CytomegalovirusGuinea Pig Cytomegalovirus (GPCMV): A Model for the Study of the Prevention and Treatment of Maternal-Fetal Transmission.A Novel Non-Replication-Competent Cytomegalovirus Capsid Mutant Vaccine Strategy Is Effective in Reducing Congenital Infection.Developing a Vaccine against Congenital Cytomegalovirus (CMV) Infection: What Have We Learned from Animal Models? Where Should We Go Next?The essential role of guinea pig cytomegalovirus (GPCMV) IE1 and IE2 homologs in viral replication and IE1-mediated ND10 targeting.Guinea pig cytomegalovirus GP84 is a functional homolog of the human cytomegalovirus (HCMV) UL84 gene that can complement for the loss of UL84 in a chimeric HCMV.
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Expression of the human cytomegalovirus UL97 gene in a chimeric guinea pig cytomegalovirus (GPCMV) results in viable virus with increased susceptibility to ganciclovir and maribavir.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 14 February 2008
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Expression of the human cytome ...... to ganciclovir and maribavir.
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Expression of the human cytome ...... ric guinea pig cytomegalovirus
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type
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Expression of the human cytome ...... to ganciclovir and maribavir.
@en
Expression of the human cytome ...... ric guinea pig cytomegalovirus
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prefLabel
Expression of the human cytome ...... to ganciclovir and maribavir.
@en
Expression of the human cytome ...... ric guinea pig cytomegalovirus
@nl
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Expression of the human cytome ...... to ganciclovir and maribavir.
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Alistair McGregor
K Yeon Choi
Mark R Schleiss
Michael A McVoy
Xiaohong Cui
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P304
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10.1016/J.ANTIVIRAL.2008.01.008
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2008-02-14T00:00:00Z