Activation of the TRPV4 ion channel is enhanced by phosphorylation.
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AKAP79, PKC, PKA and PDE4 participate in a Gq-linked muscarinic receptor and adenylate cyclase 2 cAMP signalling complexInternational Union of Basic and Clinical Pharmacology. LXXVI. Current progress in the mammalian TRP ion channel familyRegulation of transient receptor potential channels by the phospholipase C pathwayImportance of non-selective cation channel TRPV4 interaction with cytoskeleton and their reciprocal regulations in cultured cellsThe cAMP Signaling Pathway and Direct Protein Kinase A Phosphorylation Regulate Polycystin-2 (TRPP2) Channel FunctionLocal control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscleAKAP150-dependent cooperative TRPV4 channel gating is central to endothelium-dependent vasodilation and is disrupted in hypertension.Rho-kinase inhibitor Y-27632 and hypoxia synergistically enhance chondrocytic phenotype and modify S100 protein profiles in human chondrosarcoma cells.Determinants of TRPV4 activity following selective activation by small molecule agonist GSK1016790A.Increased basal activity is a key determinant in the severity of human skeletal dysplasia caused by TRPV4 mutationsPKCε phosphorylation of the sodium channel NaV1.8 increases channel function and produces mechanical hyperalgesia in mice.The increased activity of TRPV4 channel in the astrocytes of the adult rat hippocampus after cerebral hypoxia/ischemia.Involvement of protein kinase C and protein kinase A in the enhancement of L-type calcium current by GABAB receptor activation in neonatal hippocampus.Mutation of a putative S-nitrosylation site of TRPV4 protein facilitates the channel activatesInhibition of protein kinase Cβ reverses increased blood-brain barrier permeability during hyperglycemic stroke and prevents edema formation in vivo.Shear stress mediates exocytosis of functional TRPV4 channels in endothelial cells.PKCα mediates acetylcholine-induced activation of TRPV4-dependent calcium influx in endothelial cells.Function of transient receptor potential cation channel subfamily V member 4 (TRPV4) as a mechanical transducer in flow-sensitive segments of renal collecting duct system.TRPV4 in porcine lens epithelium regulates hemichannel-mediated ATP release and Na-K-ATPase activityP2Y1 Receptor Activation of the TRPV4 Ion Channel Enhances Purinergic Signaling in Satellite Glial Cells.TRPV4 dysfunction promotes renal cystogenesis in autosomal recessive polycystic kidney disease.Arachidonic acid-induced dilation in human coronary arterioles: convergence of signaling mechanisms on endothelial TRPV4-mediated Ca2+ entryDiscrete control of TRPV4 channel function in the distal nephron by protein kinases A and C.Epac-protein kinase C alpha signaling in purinergic P2X3R-mediated hyperalgesia after inflammationRole of endothelial TRPV4 channels in vascular actions of the endocannabinoid, 2-arachidonoylglycerol.TRPV4 channel contributes to serotonin-induced pulmonary vasoconstriction and the enhanced vascular reactivity in chronic hypoxic pulmonary hypertension.Roles of reactive oxygen and nitrogen species in painCross-talk between calcium and protein kinase A in the regulation of cell migration.The thermo-TRP ion channel family: properties and therapeutic implications.Computational prediction of eukaryotic phosphorylation sites.Current perspectives on the modulation of thermo-TRP channels: new advances and therapeutic implications.Protein kinase C modulation of thermo-sensitive transient receptor potential channels: Implications for pain signaling.Molecular mechanism of TRP channelsIon channels and osteoarthritic pain: potential for novel analgesics.Transient receptor potential ion channels in primary sensory neurons as targets for novel analgesics.TRPV4: physiological role and therapeutic potential in respiratory diseases.Distance constraints on activation of TRPV4 channels by AKAP150-bound PKCα in arterial myocytes.Functional expression of TRPV channels in T cells and their implications in immune regulation.S100A1 and S100B: Calcium Sensors at the Cross-Roads of Multiple Chondrogenic Pathways.Activation of TRPV4 channel in pancreatic INS-1E beta cells enhances glucose-stimulated insulin secretion via calcium-dependent mechanisms.
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Activation of the TRPV4 ion channel is enhanced by phosphorylation.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
@pt
bilimsel makale
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scientific article published on 06 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Activation of the TRPV4 ion channel is enhanced by phosphorylation.
@en
Activation of the TRPV4 ion channel is enhanced by phosphorylation.
@nl
type
label
Activation of the TRPV4 ion channel is enhanced by phosphorylation.
@en
Activation of the TRPV4 ion channel is enhanced by phosphorylation.
@nl
prefLabel
Activation of the TRPV4 ion channel is enhanced by phosphorylation.
@en
Activation of the TRPV4 ion channel is enhanced by phosphorylation.
@nl
P2860
P356
P1476
Activation of the TRPV4 ion channel is enhanced by phosphorylation
@en
P2093
Hueng-Chuen Fan
P2860
P304
27884-27891
P356
10.1074/JBC.M109.028803
P407
P577
2009-08-06T00:00:00Z