Tumour hypoxia causes DNA hypermethylation by reducing TET activity. - Wikidata - wikimedia - TriplyDB

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

http://www.wikidata.org/entity/Q37463942

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Epigenetic determinants of metastasis Mechanisms of metabolic memory and renal hypoxia as a therapeutic target in diabetic kidney disease.Targeting the vasculature in hepatocellular carcinoma treatment: Starving versus normalizing blood supply.Hypoxia inducible factors regulate the transcription of the sprouty2 gene and expression of the sprouty2 protein Association of 5-hydroxymethylation and 5-methylation of DNA cytosine with tissue-specific gene expression.The application of genome-wide 5-hydroxymethylcytosine studies in cancer research.Metabolic interactions in cancer: cellular metabolism at the interface between the microenvironment, the cancer cell phenotype and the epigenetic landscape.Antiangiogenic tyrosine kinase inhibitors in colorectal cancer: is there a path to making them more effective?Hypoxia inducible factors in hepatocellular carcinoma Histone H3.3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPG.Linking the Epigenome with Exposure Effects and Susceptibility: The Epigenetic Seed and Soil Model.The α-ketoglutarate dehydrogenase complex in cancer metabolic plasticity.The epigenetic landscape related to reactive oxygen species formation in the cardiovascular system.How to stomach an epigenetic insult: the gastric cancer epigenome.Metabolic Regulation of the Immune Humoral Response.8-Oxo-7,8-dihydroguanine, friend and foe: Epigenetic-like regulator versus initiator of mutagenesis.Epigenetic plasticity and the hallmarks of cancer.Single-cell time-lapse imaging of intracellular O2 in response to metabolic inhibition and mitochondrial cytochrome-c release.MicroRNA expression in a phosphaturic mesenchymal tumour.Oxygen nanobubbles revert hypoxia by methylation programming.Tumors smother their epigenome.IDH1 or -2 mutations do not predict outcome and do not cause loss of 5-hydroxymethylcytosine or altered histone modifications in central chondrosarcomas.A review of the basics of mitochondrial bioenergetics, metabolism, and related signaling pathways in cancer cells: Therapeutic targeting of tumor mitochondria with lipophilic cationic compounds.3D collagen architecture induces a conserved migratory and transcriptional response linked to vasculogenic mimicry.Tet1 facilitates hypoxia tolerance by stabilizing the HIF-α proteins independent of its methylcytosine dioxygenase activity.Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health.Significant associations between driver gene mutations and DNA methylation alterations across many cancer types.The chemistries and consequences of DNA and RNA methylation and demethylation.Pulmonary function impairment predicted poor prognosis of patients with hepatocellular carcinoma after hepatectomy.Improvement of Foxp3 stability through CNS2 demethylation by TET enzyme induction and activation.Elastic Multi-scale Mechanisms: Computation and Biological Evolution.Oxygen availability and metabolic reprogramming in cancer.PSL Chemical Biology Symposia First 2016 Edition: When Chemistry and Biology Share the Language of Discovery.Diallyl trisulfides, a natural histone deacetylase inhibitor, attenuate HIF-1α synthesis, and decreases breast cancer metastasis.Oxygen gradients can determine epigenetic asymmetry and cellular differentiation via differential regulation of Tet activity in embryonic stem cells.The TET enzymes.Consequences of VHL Loss on Global DNA Methylome.Metabolism, Activity, and Targeting of D- and L-2-Hydroxyglutarates.Metabolic implications of hypoxia and pseudohypoxia in pheochromocytoma and paraganglioma.Beyond Brooding on Oncometabolic Havoc in IDH-Mutant Gliomas and AML: Current and Future Therapeutic Strategies.

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Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

http://www.wikidata.org/entity/Q37463942

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on 17 August 2016

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

@en

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

@nl

type

label

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

@en

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

@nl

prefLabel

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

@en

Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

@nl

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Tumour hypoxia causes DNA hypermethylation by reducing TET activity.

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Anna Kuchnio

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Athanasios Ploumakis

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Bart Ghesquière

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Bram Boeckx

http://www.w3.org/2001/XMLSchema#string

Els Hermans

http://www.w3.org/2001/XMLSchema#string

Frederic Amant

http://www.w3.org/2001/XMLSchema#string

Hui Zhao

http://www.w3.org/2001/XMLSchema#string

Jessica Steinbacher

http://www.w3.org/2001/XMLSchema#string

Laurien Van Dyck

http://www.w3.org/2001/XMLSchema#string

Luc Schoonjans

http://www.w3.org/2001/XMLSchema#string

P2860

Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity

Cancer genome landscapes

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

The Cancer Genome Atlas Pan-Cancer analysis project

Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

Hypoxia-inducible factors and the response to hypoxic stress

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

Selective small molecule probes for the hypoxia inducible factor (HIF) prolyl hydroxylases

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63-68

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scholarly article

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10.1038/NATURE19081

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7618

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537

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Peter Carmeliet

Diether Lambrechts

Vessela Kristensen

Bernard Thienpont

Massimiliano Mazzone

Mathew L Coleman

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2016-08-17T00:00:00Z

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27533040

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