A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).

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The EMT spectrum and therapeutic opportunities.The hypoxic tumour microenvironment.

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A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).

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http://www.wikidata.org/entity/Q37465906

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article científic

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article scientifique

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articolo scientifico

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artigo científico

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bilimsel makale

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scientific article published on 13 October 2016

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vedecký článok

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vetenskaplig artikel

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videnskabelig artikel

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vědecký článek

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A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).

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A new dimension in drug discovery: reversing epithelial-mesenchymal transition

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A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).

@en

A new dimension in drug discovery: reversing epithelial-mesenchymal transition

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A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).

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A new dimension in drug discovery: reversing epithelial-mesenchymal transition

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A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).

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Ruby Yun-Ju Huang

http://www.w3.org/2001/XMLSchema#string

Thomas Yo-Yan Huang

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The transcription factor grainyhead-like 2 regulates the molecular composition of the epithelial apical junctional complex

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Screening therapeutic EMT blocking agents in a three-dimensional microenvironment

Snail mediates E-cadherin repression by the recruitment of the Sin3A/histone deacetylase 1 (HDAC1)/HDAC2 complex.

An epithelial marker promoter induction screen identifies histone deacetylase inhibitors to restore epithelial differentiation and abolishes anchorage independence growth in cancers.

GRHL2-miR-200-ZEB1 maintains the epithelial status of ovarian cancer through transcriptional regulation and histone modification.

An EMT spectrum defines an anoikis-resistant and spheroidogenic intermediate mesenchymal state that is sensitive to e-cadherin restoration by a src-kinase inhibitor, saracatinib (AZD0530).

Target cell movement in tumor and cardiovascular diseases based on the epithelial-mesenchymal transition concept.

An image-based, dual fluorescence reporter assay to evaluate the efficacy of shRNA for gene silencing at the single-cell level.

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e2417

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scholarly article

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10.1038/CDDIS.2016.316

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2016-10-13T00:00:00Z

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27735942

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5133983

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A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).

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P2860

P2860

A new dimension in drug discovery: reversing epithelial-mesenchymal transition (EMT).

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P577

P698

P932