Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
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Diversity and Inter-Connections in the CXCR4 Chemokine Receptor/Ligand Family: Molecular PerspectivesPredicted molecular signaling guiding photoreceptor cell migration following transplantation into damaged retina.The Anti-inflammatory Protein TSG-6 Regulates Chemokine Function by Inhibiting Chemokine/Glycosaminoglycan InteractionsMultiple glycosaminoglycan-binding epitopes of monocyte chemoattractant protein-3/CCL7 enable it to function as a non-oligomerizing chemokine.Emerging concepts and approaches for chemokine-receptor drug discovery.Characterization of the chemokine CXCL11-heparin interaction suggests two different affinities for glycosaminoglycans.Chemokine cooperativity is caused by competitive glycosaminoglycan binding.Chemokine (C-X-C motif) receptor 4 and atypical chemokine receptor 3 regulate vascular α₁-adrenergic receptor function.Heparan sulfate inhibits hematopoietic stem and progenitor cell migration and engraftment in mucopolysaccharidosis I.Chemokine and chemokine receptor structure and interactions: implications for therapeutic strategies.Chemokine receptor CXCR3 agonist prevents human T-cell migration in a humanized model of arthritic inflammationTouch of chemokines.Differential structural remodelling of heparan sulfate by chemokines: the role of chemokine oligomerization.CCL2 nitration is a negative regulator of chemokine-mediated inflammation.Chemokine oligomerization and interactions with receptors and glycosaminoglycans: the role of structural dynamics in functionChemokines: established and novel targets in atherosclerosis.Structure-based design of decoy chemokines as a way to explore the pharmacological potential of glycosaminoglycans.G protein-coupled receptors in rheumatology.The CXCL12/CXCR4 chemokine ligand/receptor axis in cardiovascular disease.The sweet spot: how GAGs help chemokines guide migrating cells.Essential role of immobilized chemokine CXCL12 in the regulation of the humoral immune response.Regulation of Chemokine Function: The Roles of GAG-Binding and Post-Translational NitrationHomeostatic and tissue reparation defaults in mice carrying selective genetic invalidation of CXCL12/proteoglycan interactions.CXCL12γ isoform is expressed on endothelial and dendritic cells in rheumatoid arthritis synovium and regulates T cell activation.Endothelial expression of CXCR7 and the regulation of systemic CXCL12 levels.
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P2860
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
description
article científic
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article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 10 August 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
@en
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
@nl
type
label
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
@en
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
@nl
prefLabel
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
@en
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
@nl
P2093
P2860
P356
P1433
P1476
Anti-inflammatory therapy by intravenous delivery of non-heparan sulfate-binding CXCL12.
@en
P2093
Graeme O'Boyle
John A Kirby
Paul Mellor
P2860
P304
P356
10.1096/FJ.09-134643
P407
P577
2009-08-10T00:00:00Z