Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1xGTP pathway.
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Amelioration of acute sequelae of blast induced mild traumatic brain injury by N-acetyl cysteine: a double-blind, placebo controlled studyDendritic spine pathology in schizophreniaConversion of psychological stress into cellular stress response: roles of the sigma-1 receptor in the processRecent Advances in Neurogenic Small Molecules as Innovative Treatments for Neurodegenerative DiseasesAllosteric Modulation of Sigma-1 Receptors Elicits Rapid Antidepressant ActivityPotential Molecular Mechanisms on the Role of the Sigma-1 Receptor in the Action of Cocaine and MethamphetamineUCP2 induced by natural birth regulates neuronal differentiation of the hippocampus and related adult behaviorDynamic interaction between sigma-1 receptor and Kv1.2 shapes neuronal and behavioral responses to cocainePhospholipase C, Ca2+, and calmodulin signaling are required for 5-HT2A receptor-mediated transamidation of Rac1 by transglutaminaseSigma-1 receptor chaperones in neurodegenerative and psychiatric disordersThe sigma-1 receptor chaperone as an inter-organelle signaling modulatorMitochondrial protection by the mixed muscarinic/σ1 ligand ANAVEX2-73, a tetrahydrofuran derivative, in Aβ25-35 peptide-injected mice, a nontransgenic Alzheimer's disease model.Paradoxical relationship between Mn superoxide dismutase deficiency and radiation-induced cognitive defects.Neuropharmacology of N,N-dimethyltryptamineThe Sigma-1 Receptor as a Pluripotent Modulator in Living Systems.Targeting ligand-operated chaperone sigma-1 receptors in the treatment of neuropsychiatric disorders.Sigma-1 receptor chaperone at the ER-mitochondrion interface mediates the mitochondrion-ER-nucleus signaling for cellular survivalEfficacy of N-acetyl cysteine in traumatic brain injuryPharmacological stimulation of sigma-1 receptors has neurorestorative effects in experimental parkinsonism.A Role for Sigma Receptors in Stimulant Self Administration and Addiction.Sigma-1 receptor directly interacts with Rac1-GTPase in the brain mitochondriaSigma-1 receptor regulates Tau phosphorylation and axon extension by shaping p35 turnover via myristic acid.The sigma-1 receptor protects against cellular oxidative stress and activates antioxidant response elements.Sigma 1 receptor regulates the oxidative stress response in primary retinal Müller glial cells via NRF2 signaling and system xc(-), the Na(+)-independent glutamate-cystine exchanger.The sigma-1 receptor mediates the beneficial effects of pridopidine in a mouse model of Huntington diseaseSigma-1 receptor mediates cocaine-induced transcriptional regulation by recruiting chromatin-remodeling factors at the nuclear envelopeThe sigma-1 receptor: roles in neuronal plasticity and diseaseA role for sigma receptors in stimulant self-administration and addiction.Preface.Insights into the Sigma-1 receptor chaperone's cellular functions: a microarray report.Activation of the molecular chaperone, sigma 1 receptor, preserves cone function in a murine model of inherited retinal degeneration.Transactivation of TrkB by Sigma-1 receptor mediates cocaine-induced changes in dendritic spine density and morphology in hippocampal and cortical neurons.A possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue protection, regeneration, and immunity.Dendritic spines: the locus of structural and functional plasticity.Sigma-1 Receptors and Neurodegenerative Diseases: Towards a Hypothesis of Sigma-1 Receptors as Amplifiers of Neurodegeneration and Neuroprotection.Loss-of-function mutations in the SIGMAR1 gene cause distal hereditary motor neuropathy by impairing ER-mitochondria tethering and Ca2+ signalling.Sigma-1 (σ1) Receptor in Memory and Neurodegenerative Diseases.Chloroquine inhibits glutamate-induced death of a neuronal cell line by reducing reactive oxygen species through sigma-1 receptor.Repositioning drugs for traumatic brain injury - N-acetyl cysteine and PhenserineLoss of Sigma-1 Receptor Chaperone Promotes Astrocytosis and Enhances the Nrf2 Antioxidant Defense.
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P2860
Sigma-1 receptors regulate hippocampal dendritic spine formation via a free radical-sensitive mechanism involving Rac1xGTP pathway.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 11 December 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
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vědecký článek
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name
Sigma-1 receptors regulate hip ...... sm involving Rac1xGTP pathway.
@en
Sigma-1 receptors regulate hip ...... sm involving Rac1xGTP pathway.
@nl
type
label
Sigma-1 receptors regulate hip ...... sm involving Rac1xGTP pathway.
@en
Sigma-1 receptors regulate hip ...... sm involving Rac1xGTP pathway.
@nl
prefLabel
Sigma-1 receptors regulate hip ...... sm involving Rac1xGTP pathway.
@en
Sigma-1 receptors regulate hip ...... sm involving Rac1xGTP pathway.
@nl
P2093
P2860
P356
P1476
Sigma-1 receptors regulate hip ...... sm involving Rac1xGTP pathway.
@en
P2093
Barry J Hoffer
Brandon K Harvey
Rong-Fong Shen
Shang-Yi Tsai
Teruo Hayashi
Tsung-Ping Su
Wells W Wu
Yongqing Zhang
P2860
P304
22468-22473
P356
10.1073/PNAS.0909089106
P407
P577
2009-12-11T00:00:00Z