Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity.
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Check MAIT.Development of invariant natural killer T cells.The self-obsession of T cells: how TCR signaling thresholds affect fate 'decisions' and effector function.The transcription factor lymphoid enhancer factor 1 controls invariant natural killer T cell expansion and Th2-type effector differentiation.Zbtb16 (PLZF) is stably suppressed and not inducible in non-innate T cells via T cell receptor-mediated signaling.Mouse and Human CD1d-Self-Lipid Complexes Are Recognized Differently by Murine Invariant Natural Killer T Cell ReceptorsCDR3β sequence motifs regulate autoreactivity of human invariant NKT cell receptors.Function and expression of CD1d and invariant natural killer T-cell receptor in the cotton rat (Sigmodon hispidus).Endogenous lipid antigens for invariant Natural Killer T cells hold the reins in adipose tissue homeostasis.The hypervariable region 4 (HV4) and position 93 of the α chain modulate CD1d-glycolipid binding of iNKT TCRs.Key Residues at Third CDR3β Position Impact Structure and Antigen Recognition of Human Invariant NK TCRs.Discrete TCR Binding Kinetics Control Invariant NKT Cell Selection and Central Priming.
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Effective functional maturation of invariant natural killer T cells is constrained by negative selection and T-cell antigen receptor affinity.
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 16 December 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Effective functional maturatio ...... ell antigen receptor affinity.
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Effective functional maturatio ...... ell antigen receptor affinity.
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type
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Effective functional maturatio ...... ell antigen receptor affinity.
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Effective functional maturatio ...... ell antigen receptor affinity.
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Effective functional maturatio ...... ell antigen receptor affinity.
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Effective functional maturatio ...... ell antigen receptor affinity.
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P2093
P2860
P50
P356
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Effective functional maturatio ...... ell antigen receptor affinity.
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P2093
Jennifer L Matsuda
Jingjing Zhang
Romain Bedel
P2860
P304
P356
10.1073/PNAS.1320777110
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P50
P577
2013-12-16T00:00:00Z