Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis.
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Genetically engineered ERα-positive breast cancer mouse models.Dense collagen-I matrices enhance pro-tumorigenic estrogen-prolactin crosstalk in MCF-7 and T47D breast cancer cells.Longitudinal noninvasive imaging of progesterone receptor as a predictive biomarker of tumor responsiveness to estrogen deprivation therapy.Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.Adaptive Immune Regulation of Mammary Postnatal OrganogenesisModeling prolactin actions in breast cancer in vivo: insights from the NRL-PRL mouse.Novel ERα positive breast cancer model with estrogen independent growth in the bone microenvironment.Dysregulation of SOCS-Mediated Negative Feedback of Cytokine Signaling in Carcinogenesis and Its Significance in Cancer Treatment.The JAK-STAT pathway: impact on human disease and therapeutic interventionTruncating Prolactin Receptor Mutations Promote Tumor Growth in Murine Estrogen Receptor-Alpha Mammary Carcinomas.Pathobiology of the 129:Stat1 -/- mouse model of human age-related ER-positive breast cancer with an immune infiltrate-excluded phenotypeA mutation in the viral sensor 2'-5'-oligoadenylate synthetase 2 causes failure of lactation.Aging Mouse Models Reveal Complex Tumor-Microenvironment Interactions in Cancer Progression.The Multifaceted Role of STAT3 in Mammary Gland Involution and Breast CancerMammary Stem Cells and Breast Cancer Stem Cells: Molecular Connections and Clinical Implications
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Dysregulated STAT1-SOCS1 control of JAK2 promotes mammary luminal progenitor cell survival and drives ERα(+) tumorigenesis.
description
article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 September 2013
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Dysregulated STAT1-SOCS1 contr ...... r cell survival and drives ERα
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Dysregulated STAT1-SOCS1 contr ...... d drives ERα(+) tumorigenesis.
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type
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Dysregulated STAT1-SOCS1 contr ...... r cell survival and drives ERα
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Dysregulated STAT1-SOCS1 contr ...... d drives ERα(+) tumorigenesis.
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prefLabel
Dysregulated STAT1-SOCS1 contr ...... r cell survival and drives ERα
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Dysregulated STAT1-SOCS1 contr ...... d drives ERα(+) tumorigenesis.
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Dysregulated STAT1-SOCS1 contr ...... d drives ERα(+) tumorigenesis.
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C G Rickert
D Bhattacharya
D C Allred
J Archambault
K C F Sheehan
M V Lorenzi
R D Schreiber
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10.1038/CDD.2013.116
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2013-09-13T00:00:00Z