Enabling a systems biology approach to immunology: focus on innate immunity.
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Using biological networks to integrate, visualize and analyze genomics dataModeling-Enabled Systems Nutritional ImmunologySystems biology applied to vaccine and immunotherapy developmentHuman genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon responseConsensus statement understanding health and malnutrition through a systems approach: the ENOUGH program for early lifeImmunogenomics and systems biology of vaccines.A systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections.Curating the innate immunity interactome.Protein biomarkers of periodontitis in saliva.Technical note: proteomic approaches to fundamental questions about neutrophil biology.Controlling the response: predictive modeling of a highly central, pathogen-targeted core response module in macrophage activation.High-throughput discovery of broad-spectrum peptide antibiotics.Genetic associations with micronutrient levels identified in immune and gastrointestinal networks.New approaches to design HIV-1 T-cell vaccinesNetwork topologies and dynamics leading to endotoxin tolerance and priming in innate immune cells.Systems vaccinology.Barriers to the effective treatment of sepsis: antimicrobial agents, sepsis definitions, and host-directed therapies.A strategy to study pathway cross-talks of cells under repetitive exposure to stimuli.Applying principles from complex systems to studying the efficacy of CAM therapies.Structural principles within the human-virus protein-protein interaction network.A systems biological approach reveals multiple crosstalk mechanism between gram-positive and negative bacterial infections: an insight into core mechanism and unique molecular signatures.A systems biology approach to the analysis of subset-specific responses to lipopolysaccharide in dendritic cells.The human transcriptome during nontyphoid Salmonella and HIV coinfection reveals attenuated NFkappaB-mediated inflammation and persistent cell cycle disruption.Systems-biology approaches to discover anti-viral effectors of the human innate immune response.Integrative Genomics-Based Discovery of Novel Regulators of the Innate Antiviral ResponsePBMC transcriptome profiles identifies potential candidate genes and functional networks controlling the innate and the adaptive immune response to PRRSV vaccine in Pietrain pigInnateDB: systems biology of innate immunity and beyond--recent updates and continuing curationMachine learning analysis of the relationship between changes in immunological parameters and changes in resistance to Listeria monocytogenes: a new approach for risk assessment and systems immunology.Immunoinformatics: an integrated scenario.Antimicrobial peptides: successes, challenges and unanswered questions.How has research into cytokine interactions and their role in driving immune responses impacted our understanding of periodontitis?Modulating immunity as a therapy for bacterial infections.Systems biology of host-fungus interactions: turning complexity into simplicityA global "imaging'' view on systems approaches in immunology.Immune modulation by multifaceted cationic host defense (antimicrobial) peptides.Current transcriptomics in pig immunity research.Understanding innate immunity and inflammation in acne: implications for management.Genomewide effects of peroxisome proliferator-activated receptor gamma in macrophages and dendritic cells--revealing complexity through systems biology.How does our increased understanding of the role of inflammation and innate immunity in acne impact treatment approaches?DC-ATLAS: a systems biology resource to dissect receptor specific signal transduction in dendritic cells.
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Enabling a systems biology approach to immunology: focus on innate immunity.
description
article científic
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article scientifique
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articolo scientifico
@it
artigo científico
@pt
bilimsel makale
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scientific article published on 08 May 2009
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Enabling a systems biology approach to immunology: focus on innate immunity.
@en
Enabling a systems biology approach to immunology: focus on innate immunity.
@nl
type
label
Enabling a systems biology approach to immunology: focus on innate immunity.
@en
Enabling a systems biology approach to immunology: focus on innate immunity.
@nl
prefLabel
Enabling a systems biology approach to immunology: focus on innate immunity.
@en
Enabling a systems biology approach to immunology: focus on innate immunity.
@nl
P2093
P356
P1433
P1476
Enabling a systems biology approach to immunology: focus on innate immunity.
@en
P2093
David J Lynn
Fiona S L Brinkman
Jennifer L Gardy
P304
P356
10.1016/J.IT.2009.03.009
P577
2009-05-08T00:00:00Z