Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease
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B cells in chronic graft-versus-host diseaseThe Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical OverviewThe Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host DiseaseAdministration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effectsAberrant B-cell homeostasis in chronic GVHDInhibition of BTK and ITK with Ibrutinib Is Effective in the Prevention of Chronic Graft-versus-Host Disease in MiceDendritic cells and regulation of graft-versus-host disease and graft-versus-leukemia activity.Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host diseaseAntibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice.Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells.Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease.Host APCs augment in vivo expansion of donor natural regulatory T cells via B7H1/B7.1 in allogeneic recipientsLoss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease.Mouse models of graft-versus-host disease: advances and limitationsTherapeutic benefits targeting B-cells in chronic graft-versus-host disease.Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD.Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.Long-Lasting Graft-Derived Donor T Cells Contribute to the Pathogenesis of Chronic Graft-versus-Host Disease in Mice.
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P2860
Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease
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article científic
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article scientifique
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articolo scientifico
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artigo científico
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bilimsel makale
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scientific article published on 13 December 2010
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vedecký článok
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vetenskaplig artikel
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videnskabelig artikel
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vědecký článek
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name
Alloimmune response results in ...... onic graft-versus-host disease
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Alloimmune response results in ...... nic graft-versus-host disease.
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type
label
Alloimmune response results in ...... onic graft-versus-host disease
@en
Alloimmune response results in ...... nic graft-versus-host disease.
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Alloimmune response results in ...... onic graft-versus-host disease
@en
Alloimmune response results in ...... nic graft-versus-host disease.
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P2093
P2860
P356
P1476
Alloimmune response results in ...... onic graft-versus-host disease
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P2093
Dongchang Zhao
Elizabeth Shen
Ivan Todorov
James S Young
Peiguo G Chu
Stephen J Forman
Tangsheng Yi
Yu-Hong Chen
P2860
P304
P356
10.4049/JIMMUNOL.1002195
P407
P577
2010-12-13T00:00:00Z