Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease - Wikidata - wikimedia - TriplyDB

Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease

Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease

http://www.wikidata.org/entity/Q37479204

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B cells in chronic graft-versus-host disease The Role of Animal Models in the Study of Hematopoietic Stem Cell Transplantation and GvHD: A Historical Overview The Biology of Chronic Graft-versus-Host Disease: A Task Force Report from the National Institutes of Health Consensus Development Project on Criteria for Clinical Trials in Chronic Graft-versus-Host Disease Administration of anti-CD20 mAb is highly effective in preventing but ineffective in treating chronic graft-versus-host disease while preserving strong graft-versus-leukemia effects Aberrant B-cell homeostasis in chronic GVHD Inhibition of BTK and ITK with Ibrutinib Is Effective in the Prevention of Chronic Graft-versus-Host Disease in Mice Dendritic cells and regulation of graft-versus-host disease and graft-versus-leukemia activity.Emergence of T cells that recognize nonpolymorphic antigens during graft-versus- host disease Antibodies from donor B cells perpetuate cutaneous chronic graft-versus-host disease in mice.Thymic damage, impaired negative selection, and development of chronic graft-versus-host disease caused by donor CD4+ and CD8+ T cells.Donor B cells in transplants augment clonal expansion and survival of pathogenic CD4+ T cells that mediate autoimmune-like chronic graft-versus-host disease.Host APCs augment in vivo expansion of donor natural regulatory T cells via B7H1/B7.1 in allogeneic recipients Loss of B7-H1 expression by recipient parenchymal cells leads to expansion of infiltrating donor CD8+ T cells and persistence of graft-versus-host disease.Mouse models of graft-versus-host disease: advances and limitations Therapeutic benefits targeting B-cells in chronic graft-versus-host disease.Corruption of dendritic cell antigen presentation during acute GVHD leads to regulatory T-cell failure and chronic GVHD.Extrafollicular CD4+ T-B interactions are sufficient for inducing autoimmune-like chronic graft-versus-host disease.Long-Lasting Graft-Derived Donor T Cells Contribute to the Pathogenesis of Chronic Graft-versus-Host Disease in Mice.

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Alloimmune response results in expansion of autoreactive donor CD4+ T cells in transplants that can mediate chronic graft-versus-host disease

http://www.wikidata.org/entity/Q37479204

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bilimsel makale

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scientific article published on 13 December 2010

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Alloimmune response results in ...... onic graft-versus-host disease

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Alloimmune response results in ...... nic graft-versus-host disease.

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Alloimmune response results in ...... onic graft-versus-host disease

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Alloimmune response results in ...... onic graft-versus-host disease

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JIMMUNOL.1002195

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Journal of Immunology

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Alloimmune response results in ...... onic graft-versus-host disease

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Defu Zeng

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Dongchang Zhao

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Elizabeth Shen

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Ivan Todorov

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James S Young

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Peiguo G Chu

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Stephen J Forman

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Tangsheng Yi

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Yu-Hong Chen

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Prediction of graft-versus-host disease in humans by donor gene-expression profiling

Thymus: a direct target tissue in graft-versus-host reaction after allogeneic bone marrow transplantation that results in abrogation of induction of self-tolerance.

Salivary gland involvement in chronic graft-versus-host disease: prevalence, clinical significance, and recommendations for evaluation.

Association of BAFF/BLyS overexpression and altered B cell differentiation with Sjögren's syndrome

Cutting edge: Highly alloreactive dual TCR T cells play a dominant role in graft-versus-host disease.

Mice lacking all conventional MHC class II genes.

Influence of T-cell depletion on chronic graft-versus-host disease: results of a multicenter randomized trial in unrelated marrow donor transplantation.

Prevention of graft-versus-host disease by anti IL-7Ralpha antibody.

Absence of regulatory T-cell control of TH1 and TH17 cells is responsible for the autoimmune-mediated pathology in chronic graft-versus-host disease.

Shared biology of GVHD and GVT effects: potential methods of separation.

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10.4049/JIMMUNOL.1002195

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